| Brainstorm | Updates for Brazil: +36674 cases, +36 deaths since 20 hours ago — Thailand: +27866 cases, +941 deaths since 20 hours ago — Ethiopia: +99 cases since a day ago — Albania: +47 cases since a day ago | 00:04 |
|---|---|---|
| Brainstorm | New from COVID on Twitter: Marc Veldhoen (@Marc_Veld): No evidence of vaccine effect, figures up to June 2022 looking at deaths from all causes show unvaccinated people were more likely to die than vaccinated people. If vaccines were driving excess deaths we would expect this to be the other way around. pic.twitter.com/3PdlIkLuFC → https://twitter.com/Marc_Veld/status/1612948884333989891 | 00:15 |
| Brainstorm | Updates for Algeria: +7 cases since 22 hours ago | 01:00 |
| Brainstorm | Updates for Slovakia: +274 cases since 23 hours ago | 02:02 |
| Brainstorm | Updates for Zambia: +258 cases since 23 hours ago | 03:04 |
| Brainstorm | Updates for Trinidad and Tobago: +406 cases, +8 deaths since 7 days ago — Haiti: +57 cases since 4 days ago | 04:07 |
| Brainstorm | New from r/COVID19: COVID19: Booster vaccination protection against SARS-CoV-2 infections in young adults during an Omicron BA.1-predominant period: A retrospective cohort study → https://old.reddit.com/r/COVID19/comments/108uidi/booster_vaccination_protection_against_sarscov2/ | 04:47 |
| Brainstorm | New from COVID on Twitter: Eric Topol (@EricTopol): An outstanding appraisal of #SARSCoV2 evolution as an antigen, the potential role of immune imprinting (original antigenic sin), and strategies to prevailjci.org/articles/view/…@jclinicalinvest @MarionKoopmans @GijsbertNierop pic.twitter.com/LaZvpQqXNZ → https://twitter.com/EricTopol/status/1613023813838733313 | 05:15 |
| LjL | "the potential role of immune imprinting (original antigenic sin)" | 05:23 |
| LjL | finally the words can be uttered again | 05:23 |
| LjL | at some point it was almost grounds for being thrown out of a polite COVID talking room to mention that original antigenic sin might be a problem perhaps | 05:23 |
| Brainstorm | Updates for Germany: +22119 cases, +269 deaths since 23 hours ago | 05:59 |
| Brainstorm | Updates for Parana, Brazil: +18337 cases, +31 deaths since 3 days ago — Virginia, United States: +17929 cases, +136 deaths since 6 days ago — Sao Paulo, Brazil: +13243 cases, +47 deaths since 3 days ago — South Carolina, United States: +11284 cases, +134 deaths since 5 days ago | 07:01 |
| Brainstorm | New from COVID on Twitter: Marc Veldhoen (@Marc_Veld): Misinformation and mistrust is taking a heavy toll on China’s elderly, with many paying the ultimate price for vaccine hesitancy telegraph.co.uk/global-health/… → https://twitter.com/Marc_Veld/status/1613071533286506497 | 08:20 |
| Brainstorm | New from r/COVID19: COVID19: Inspiration of SARS-CoV-2 envelope protein mutations on pathogenicity of Omicron XBB → https://old.reddit.com/r/COVID19/comments/108yri4/inspiration_of_sarscov2_envelope_protein/ | 08:30 |
| Brainstorm | New from r/COVID19: COVID19: Altered gut microbiota composition in children and their caregivers infected with the SARS-CoV-2 Omicron variant → https://old.reddit.com/r/COVID19/comments/108ywod/altered_gut_microbiota_composition_in_children/ | 08:39 |
| Brainstorm | New from Reddit (test): nCoV: Pentagon Drops COVID-19 Vaccine Mandate for Troops → https://old.reddit.com/r/nCoV/comments/108z4ys/pentagon_drops_covid19_vaccine_mandate_for_troops/ | 08:59 |
| Brainstorm | Updates for Taiwan: +25631 cases, +46 deaths, +31855 tests since 23 hours ago | 09:00 |
| Brainstorm | New from r/Coronavirus: Daily Discussion Thread | January 11, 2023: Please refer to our Wiki for more information on COVID-19 and our sub. You can find answers to frequently asked questions in our FAQ , where there is valuable information such as our: → https://old.reddit.com/r/Coronavirus/comments/108z9qq/daily_discussion_thread_january_11_2023/ | 09:09 |
| Brainstorm | Updates for Japan: +176731 cases, +373 deaths since 23 hours ago | 10:02 |
| Brainstorm | New from StatNews: Will America’s public health reckoning ever come?: Despite the many failures of our Covid response, very little about U.S. pandemic infrastructure has changed. But some are still working to find compromise reforms. → https://www.statnews.com/2023/01/11/will-americas-public-health-reckoning-ever-come/ | 10:47 |
| Brainstorm | New from StatNews: Opinion: There are 4 gaps in global pandemic responses. The biggest is missing leadership: How many contagions will it take before the world finally stops tolerating preventable deaths on a massive scale and does something to prevent them? → https://www.statnews.com/2023/01/11/4-gaps-in-global-pandemic-responses-the-biggest-is-missing-leadership/ | 11:07 |
| Brainstorm | New from Reddit (test): CoronaVirus_2019_nCoV: Rapid tests for Covid, RSV and flu are available in Europe. What's stopping them in the U.S.? → https://old.reddit.com/r/CoronaVirus_2019_nCoV/comments/1091ybw/rapid_tests_for_covid_rsv_and_flu_are_available/ | 12:07 |
| Brainstorm | New from r/COVID19: COVID19: Lung Function Decline in Relation to COVID-19 in the General Population: A Matched Cohort Study With Prepandemic Assessment of Lung Function → https://old.reddit.com/r/COVID19/comments/109211j/lung_function_decline_in_relation_to_covid19_in/ | 12:16 |
| Brainstorm | New from r/COVID19: COVID19: Association Between COVID-19 and Lung Function: A Mendelian Randomization Analysis → https://old.reddit.com/r/COVID19/comments/1092gwu/association_between_covid19_and_lung_function_a/ | 12:45 |
| Brainstorm | New from Politico: Holocaust: British Tory MP loses whip after comparing COVID-19 vaccine to Holocaust → https://www.politico.eu/article/uk-conservative-mp-andrew-bridgen-lose-whip-covid-19-vaccine-holocaust/ | 12:55 |
| Brainstorm | New from Reddit (test): nCoV: Global COVID Cases For 11JAN22 → https://old.reddit.com/r/nCoV/comments/109300f/global_covid_cases_for_11jan22/ | 13:05 |
| Brainstorm | Updates for Russia: +4201 cases, +46 deaths since a day ago — Saudi Arabia: +30 cases, +3 deaths since 22 hours ago | 14:05 |
| Brainstorm | New from Contagion Live: FDA Approves Tdap Vaccine for Pregnant Mothers to Prevent Pertussis in Young Infants: The agency licensed the new indication for Sanofi’s Adacel (Tetanus Toxoid, Reduced Diphtheria Toxoid and Acellular Pertussis Vaccine, [... want %more?] → https://www.contagionlive.com/view/fda-approves-tdap-vaccine-for-pregnant-mothers-to-prevent-pertussis-in-young-infants | 14:24 |
| Brainstorm | Updates for Bangladesh: +22 cases, +1 deaths, +2317 tests since a day ago | 15:01 |
| Brainstorm | New from ScienceNews: Why it’s easier to catch a cold, the flu or COVID in the winter: Low humidity protects viruses and cold temperatures may blunt some immune responses, making viral infections like colds, flu and COVID-19 more likely. → https://www.sciencenews.org/article/why-easier-catch-cold-flu-covid-winter | 15:03 |
| Brainstorm | New from COVID on Twitter: Florian Krammer (@florian_krammer): Ich werd morgen die New Year's Lecture für das österreichische ASM Chapter geben. "Broadly protective influenza virus vaccines that target conserved epitopes of the viral surface glycoproteins" Hier das Anmeldeformular, für alle die es [... want %more?] → https://twitter.com/florian_krammer/status/1613175443712102402 | 15:13 |
| Brainstorm | New from StatNews: Pharma: STAT+: Pharmalittle: Pfizer will not license generic Covid-19 pill in China; BioMarin signs outcomes-based deal in Germany for gene therapy → https://www.statnews.com/pharmalot/2023/01/11/covid19-pfizer-merck-fda-china-biomarin-sunpharma-patents-hhs-illumina-340b/ | 15:33 |
| Brainstorm | New from COVID on Twitter: Marc Veldhoen (@Marc_Veld): Yet, Tobaco-, climate-, COVID-19-, vaccine-deniers seize upon any uncertainty and anomaly to claim to have disproven entire fields, knowledge, and combined research.They abuse the impossibility of 100% certainty and proof to divide society and create [... want %more?] → https://twitter.com/Marc_Veld/status/1613182627875532800 | 15:43 |
| Brainstorm | New from COVID on Twitter: Bloom Lab (@jbloom_lab): You can choose which virus to use as the "focal" virus when organizing the heatmap to make specific comparisons easier.For instance, here is changing the focal virus from SARS-CoV-2 (Wuhan-Hu-1) to RaTG13 for the spike identity comparisons: pic.twitter.com/Lp7Xdr1VhB → https://twitter.com/jbloom_lab/status/1613184975637184512 | 15:53 |
| Brainstorm | New from COVID on Twitter: Marc Veldhoen (@Marc_Veld): House Republicans Launch Subcommittee to Investigate Covid OriginsScience in front of committees? Once a fringe, now anti-science has gone mainstream. But "it is not political".nationalreview.com/news/house-rep… → https://twitter.com/Marc_Veld/status/1613188460986204161 | 16:03 |
| Brainstorm | Updates for Austria: +3164 cases, +19 deaths, +67796 tests since 23 hours ago | 16:09 |
| Brainstorm | New from COVID on Twitter: Marc Veldhoen (@Marc_Veld): The incidence is not greatly reduced. It is possible that physician diagnosing behavior has changed andphysicians are more likely to recognise and have adopted use of either the new U09.9 Long COVID diagnosis. → https://twitter.com/Marc_Veld/status/1613198238139486212 | 16:42 |
| Brainstorm | New from ClinicalTrials.gov: (news): An Investigator Initiated, Randomized, Double-blinded, Placebo-controlled Clinical Trial to Evaluate the Safety, Immunogenicity and Efficacy of the Recombinant Two-component COVID-19 Vaccine (CHO Cell) in Adults Aged 18 Years and Older → https://clinicaltrials.gov/ct2/show/NCT05679466 | 17:02 |
| Brainstorm | New from ClinicalTrials.gov: (news): SARS-CoV-2 Infection Among Healthcare Workers → https://clinicaltrials.gov/ct2/show/NCT05680896 | 17:31 |
| Brainstorm | New from ClinicalTrials.gov: (news): Prevalence of Thrombophilic Gene Polymorphism (MTHFR C677T) in COVID-19patients → https://clinicaltrials.gov/ct2/show/NCT05679414 | 17:51 |
| Brainstorm | New from ClinicalTrials.gov: (news): Study on the Safety and Efficacy of Meplazumab for Injection in Adults With Mild and Moderate COVID-19 Infections → https://clinicaltrials.gov/ct2/show/NCT05679492 | 18:01 |
| Brainstorm | New from Politico: Poland clears first hurdle to get EU cash: The bill survived one vote in parliament but faces many more tests ahead. → https://www.politico.eu/article/poland-hurdle-eu-cash-european-union/ | 18:11 |
| Brainstorm | New from Reddit (test): CoronaVirus_2019_nCoV: Peter Hotez on new COVID XBB1.5 variant: 'People are saying this will be mild. It's not mild' → https://old.reddit.com/r/CoronaVirus_2019_nCoV/comments/109a6la/peter_hotez_on_new_covid_xbb15_variant_people_are/ | 18:51 |
| Brainstorm | Updates for Indiana, United States: +24894 cases since 4 days ago | 19:04 |
| LjL | Only four member states used the EU digital passenger locator form and, of almost 27 million forms issued by February 2022, more than nine in 10 were issued by a single EU country, Italy, ECA found. | 19:17 |
| LjL | https://www.euractiv.com/section/coronavirus/news/europe-has-not-used-potential-of-covid-tools-to-ease-travel-eu-auditors-say/ | 19:17 |
| LjL | In the meantime, the exchange platform was hardly used at all, with only 256 forms by the end of February 2022, all but one from Spain. | 19:18 |
| LjL | The uptake of contact-tracing applications varied significantly: By May 2022, the vast majority of data on the gateway was generated by users from Germany alone. | 19:18 |
| LjL | (we had sort of noticed) | 19:18 |
| Brainstorm | New from COVID on Twitter: Marc Veldhoen (@Marc_Veld): SARS-CoV-2 interference with cellular immune signalling pic.twitter.com/R0l9za054y → https://twitter.com/Marc_Veld/status/1613237487920648192 | 19:21 |
| Brainstorm | New from COVID on Twitter: Eric Topol (@EricTopol): Immune evasion of #SARSCoV2 typically refers to our antibodies having less neutralization capacity vs new variants. But our 1st line of defense, the innate immune system—interferons—also play a critical role as elegantly reviewed nature.com/articles/s4157… [... want %more?] → https://twitter.com/EricTopol/status/1613241427496169472 | 19:31 |
| LjL | why are COVID+Flu+RSV rapid tests not being used more widely? | 19:36 |
| LjL | they are approved in Europe, we can probably just buy them, but there's little awareness | 19:36 |
| LjL | my friend in Greece might have had COVID, since he's living with someone who does, so he went to the testing center, he was negative for COVID, but nobody (neither him, except afterwards, not the nurse) thought to also test him for the flu, which at this point seems likely, as he definitely has symptoms | 19:37 |
| Brainstorm | Updates for Guatemala: +1722 cases, +6 deaths since 22 hours ago — Canada: +13 deaths since 23 hours ago | 20:00 |
| Brainstorm | New from COVID on Twitter: Eric Topol (@EricTopol): Some #SARSCoV2 mutations that confer resistance to Paxlovid have been deposited @NCBI & @GISAID science.org/doi/10.1126/sc… @ScienceTM"Our findings argue for highly selective use...because extensive, unselective use is expected to rapidly lead to emergence of [... want %more?] → https://twitter.com/EricTopol/status/1613250802159878144 | 20:11 |
| LjL | well, good, are we going to lose Paxlovid without even meaningfully USING Paxlovid in the first place? | 20:44 |
| LjL | jolly jolly good | 20:44 |
| LjL | %print https://twitter.com/BrainstormBot/status/1613264414592868355 | 21:01 |
| Brainstorm | LjL, It says: Brainstorm on Twitter: "La mortalità in eccesso, sia per #COVID, #influenza o altro, ha anche quest'anno un chiaro picco in tutta Europa: https://t.co/TT8euz3DhN Ma cercate il grafico dell'Italia... non c'è. Non siamo nel sistema di monitoraggio? Fino a pochi mesi fa, sì: https://t.co/KREzJtTrVe Ora no?" / Twitter | 21:01 |
| LjL | %tr <it https://twitter.com/BrainstormBot/status/1613264414592868355 | 21:02 |
| Brainstorm | LjL, Italian to English: Brainstorm on Twitter: "Excess mortality, whether from #COVID, #flu or other, has a clear peak again this year across Europe: https://t.co/TT8euz3DhN But look for the Italy graph.. it's not there. We're not in the monitoring system? Up until a few months ago, yes: https://t.co/KREzJtTrVe Now isn't it?" / Twitter (Google: 18%) [... want %more?] | 21:02 |
| LjL | %print https://twitter.com/EricTopol/status/1613250802159878144 | 21:11 |
| Brainstorm | LjL, It says: Eric Topol on Twitter: "Some #SARSCoV2 mutations that confer resistance to Paxlovid have been deposited @NCBI & @GISAID https://t.co/bzgje9aYqJ @ScienceTM "Our findings argue for highly selective use...because extensive, unselective use is expected to rapidly lead to emergence of drug resistance." https://t.co/hg2E0EKf25" / Twitter | 21:11 |
| LjL | pwr22, ↑ | 21:11 |
| Brainstorm | New from COVID on Twitter: Marc Veldhoen (@Marc_Veld): How to say you don't understand how a vaccine works, no idea about infections, little about biology; but not actually saying it ... pic.twitter.com/5fgc9XF53D → https://twitter.com/Marc_Veld/status/1613266379079032848 | 21:11 |
| pwr22 | LjL: Yay.... | 21:14 |
| de-facto | well if they would have restricted usage for strictly isolated problematic severe cases they could have prevented that mutations selected for circumventing the Paxlovid efficacy could have escaped into the incidence of majorities | 21:16 |
| de-facto | i mean, seriously, what did they expect when they would just subscribe it to everybody that just asked for it? | 21:16 |
| de-facto | but yeah, by restricting a treatment to only a few severe cases you dont make nearly as much money as from giving it to everybody that pays for it | 21:17 |
| LjL | are you fucking kidding me? | 21:17 |
| LjL | it's hardly being given carelessly to "everybody that just asks for it" | 21:18 |
| LjL | that's an outright insulting statement to everyone who's hoping to get it, and not getting it | 21:18 |
| LjL | https://www.nature.com/articles/d41586-022-04576-6 is the amount Paxlovid is being used | 21:21 |
| LjL | from r/WorldNews at 19:31: Moderna CEO: 400% price hike on COVID vaccine “consistent with the value” | 21:53 |
| Tuvix | Uh-huh. So they've, what, cut the time to deliver variant-targeted updates to 25% the time it took before to provide that value-add? Geez, what a mindless cash-grab. | 21:58 |
| Brainstorm | Updates for South Africa: +602 cases since a day ago | 22:10 |
| Brainstorm | New from Science Daily: Researchers take key step toward new treatment for hereditary blindness: Scientists have demonstrated in animal models the possibility of using lipid nanoparticles and messenger RNA, the technology underpinning COVID-19 vaccines, to treat blindness associated with a rare genetic condition. → https://www.sciencedaily.com/releases/2023/01/230111150800.htm | 22:40 |
| Brainstorm | Updates for Canada: +698 cases since 22 hours ago | 23:00 |
| Brainstorm | New from COVID on Twitter: Eric Topol (@EricTopol): The Covid bivalent vaccine booster works better than expected. I've reviewed the cumulative dataerictopol.substack.com/p/the-bivalent…That's in contrast to a @NEJM essay today and 2 lab studies that used a pseudovirus assay without assessing the XBB variants → https://twitter.com/EricTopol/status/1613294891370713089 | 23:10 |
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