libera/##covid-19/ Monday, 2023-01-02

BrainstormUpdates for Ethiopia: +156 cases since a day ago00:08
BrainstormNew from r/Coronavirus: Coronavirus: COVID-19 and Excess All-Cause Mortality in the US and 20 Comparison Countries, June 2021-March 2022 → https://old.reddit.com/r/Coronavirus/comments/100uoaj/covid19_and_excess_allcause_mortality_in_the_us/00:29
BrainstormNew from COVID on Twitter: Meaghan Kall (@kallmemeg): This is a very welcome development. More Chinese    genomes help us to understand which variants & mutations are emerging during their current #COVID19 waveCountries can make more robust & proportionate travel risk assessments   twitter.com/rajlabn/status… → https://twitter.com/kallmemeg/status/160970202055806976101:17
BrainstormNew from r/Science: science: Researchers find that public health trust was the strongest predictor of positive attitudes towards COVID-19 vaccination. Information literacy, science literacy, and religiosity affected attitudes to a lesser degree. → https://old.reddit.com/r/science/comments/100zzsq/researchers_find_that_public_health_trust_was_the/03:03
BrainstormNew from r/COVID19: COVID19: Lingering SARS-CoV-2 in Gastric and Gallbladder Tissues of Patients with Previous COVID-19 Infection Undergoing Bariatric Surgery → https://old.reddit.com/r/COVID19/comments/10111na/lingering_sarscov2_in_gastric_and_gallbladder/03:41
LjLde-facto, pwr22 ↑ that is scary03:49
LjLconfirms older "guts" studies03:50
LjL30% of patients still were positive to SARS-COV-2 in their stomach lining after around 300 days03:50
Asakodoes having had covid reduce innate immunity indefinitely per the new studies?03:51
LjLalthough... for a change... it looks like thy didn't *culture* it so they won't know if it's viable virus03:51
LjLAsako, not something i've heard03:51
Asakoits on TWiV or so, maybe contributing to record Flu cases this year03:54
xxrecord flu cases are the result of people completely ignoring all hygiene as a way of demonstrating freedom03:55
LjL"Viral RNA has also been found in other organs outside the gut, including the central nervous system, heart, eyes, brain (up to 230 days after infection), and breasts [14]."03:57
LjLhow fun03:58
BrainstormUpdates for Suriname: +439 cases, +5 deaths since a month ago04:05
BrainstormNew from ##covid-19 Zotero group: Lingering SARS-CoV-2 in Gastric and Gallbladder Tissues of Patients with Previous COVID-19 Infection Undergoing Bariatric Surgery: Type Journal Article Author Mohamed Hany Author Ahmed Zidan Author Muhammad Gaballa Author Mohamed Ibrahim Author Ann Samy Shafiq Agayby Author Anwar [... want %more?] → https://www.zotero.org/groups/covid_links/items/9S72Z8TW04:11
AsakoI need to decide whether to join a group 1x/week, or maybe avoid it cause of XBB or so , maybe return in February04:15
de-factoall got very high BMI and gastrointestinal symptoms during infection04:28
BrainstormNew from COVID on Twitter: Michael Lin, MD PhD   (@michaelzlin): Mini-thread on association between SARSCoV2 and premature birth or miscarriage, and on cases of SARSCoV2 in fetuses in utero (not good news)twitter.com/michaelzlin/st… → https://twitter.com/michaelzlin/status/160977111906585804805:47
BrainstormNew from COVID on Twitter: Michael Lin, MD PhD   (@michaelzlin): Pointing out that Pfizer digging up rebounds rates from their 2021 trial (all unvaxxed patients infected pre-Omicron) is attempted gaslighting using irrelevant data.Could also have written that pharma only publishes archived data when it benefits [... want %more?] → https://twitter.com/michaelzlin/status/160977475037678797005:57
BrainstormNew from COVID on Twitter: Michael Lin, MD PhD   (@michaelzlin): Mini-thread recommending the bivalent vaccine, esp Moderna (not paid by Moderna).twitter.com/michaelzlin/st… → https://twitter.com/michaelzlin/status/160977520319386009606:06
BrainstormUpdates for Germany: +1 cases since a day ago06:09
BrainstormNew from COVID on Twitter: Michael Lin, MD PhD   (@michaelzlin): My position on Pfizer's shameless money-grabNo wonder public opinion of big pharma goes *down* in a year they save millions of lives. I guess the CEOs don't care.twitter.com/michaelzlin/st… → https://twitter.com/michaelzlin/status/160978288418085274106:36
BrainstormNew from COVID on Twitter: Michael Lin, MD PhD   (@michaelzlin): Same thread as previous one, but at the end, linking to new larger studies 2 weeks later that did establish superiority of BA5+Wuhan bivalent over straight Wuhan booster:twitter.com/michaelzlin/st… → https://twitter.com/michaelzlin/status/160978712692905164906:46
BrainstormUpdates for Saint Petersburg, Russia: +728 cases, +16 deaths since 23 hours ago — Bashkortostan, Russia: +354 cases, +1 deaths since 23 hours ago — Samara, Russia: +201 cases, +1 deaths since 23 hours ago — Nuble, Chile: +169 cases, +1 deaths since 23 hours ago06:59
BrainstormNew from COVID on Twitter: Michael Lin, MD PhD   (@michaelzlin): Thread on how we're smart enough to assign blame to both the airplane manufacturer and pilot when airplanes crash, but how we've done nothing close to a comprehensive investigation of causes and responses to SARS-CoV2.twitter.com/michaelzlin/st… → https://twitter.com/michaelzlin/status/160979196129640448307:05
BrainstormNew from COVID on Twitter: Michael Lin, MD PhD   (@michaelzlin): On why a study of Paxlovid rebound rates in hospitalized patients shouldn't try to conclude anything about Paxlovid rebound rates in all COVID19 patientstwitter.com/michaelzlin/st… → https://twitter.com/michaelzlin/status/160979461615245721707:14
BrainstormNew from COVID on Twitter: Michael Lin, MD PhD   (@michaelzlin): That's it for the 2022 COVID-19 metathread. Much longer than any of us would have wanted, unfortunately. → https://twitter.com/michaelzlin/status/160979846402371175107:33
BrainstormNew from Science-Based Medicine: Was 2022 the “year of the gaslighter” with respect to COVID-19?: "Gaslighting" is a term that refers to the manipulation of someone in order to lead them to question their own reality and even sanity. Last month, a COVID-19 minimizer and [... want %more?] → https://sciencebasedmedicine.org/was-2022-the-year-of-the-gaslighter-with-respect-to-covid-19/09:08
BrainstormNew from COVID on Twitter: Tom Wenseleers (@TWenseleers): * More detailed breakdown below based on a bunch of newly submitted sequences deposited by China. In the US homegrown rapidly increasing variant XBB.1.5 that is now at 40% share clearly a much greater threat than any of this. mobile.twitter.com/RajlabN/status… → https://twitter.com/TWenseleers/status/160982684093556736009:27
BrainstormNew from r/COVID19: COVID19: Case Report of Donor Transmitted SARS-CoV-2 Infection During Lung Transplantation → https://old.reddit.com/r/COVID19/comments/1017phl/case_report_of_donor_transmitted_sarscov2/09:46
BrainstormNew from r/COVID19: COVID19: Pre-Existing Population Immunity and severe acute respiratory syndrome coronavirus 2 Variant Establishment and Dominance Dynamics in the United States: An Ecological Study → https://old.reddit.com/r/COVID19/comments/10190vu/preexisting_population_immunity_and_severe_acute/11:12
BrainstormNew from Reddit (test): Covid2019: "It is depressing to have Covid regulations in the UK for the first time in 10 months." – Jamie Walden on the emboldening of the biosecurity state. → https://old.reddit.com/r/Covid2019/comments/101acga/it_is_depressing_to_have_covid_regulations_in_the/12:30
BrainstormNew from Reddit (test): CoronaVirus_2019_nCoV: EU to discuss joint Covid response to China arrivals on Jan 4: Sweden - "the identification of possible new variants that could emerge in China could be detected with genomic sequencing of airport waste water analysis," → https://old.reddit.com/r/CoronaVirus_2019_nCoV/comments/101bjv8/eu_to_discuss_joint_covid_response_to_china/13:46
BrainstormUpdates for Romania: +3605 cases, +34 deaths since 6 days ago — Saudi Arabia: +39 cases, +1 deaths since 23 hours ago14:02
BrainstormNew from r/COVID19: Weekly Scientific Discussion Thread - January 02, 2023: This weekly thread is for scientific discussion pertaining to COVID-19. Please post questions about the science of this virus and disease here to collect them for others and clear up post space for [... want %more?] → https://old.reddit.com/r/COVID19/comments/101c23m/weekly_scientific_discussion_thread_january_02/14:06
BrainstormNew from r/COVID19: COVID19: Which curve are we flattening? The disproportionate impact of COVID-19 among economically marginalized communities in Ontario, Canada, was unchanged from wild-type to omicron → https://old.reddit.com/r/COVID19/comments/101damy/which_curve_are_we_flattening_the/15:34
BrainstormNew from Contagion Live: Medical Masks Or N95s For COVID-19 Protection in Health Care?: Although medical masks were noninferior to N95 in a multinational study of frontline health care workers, variability in circumstances between countries prevented researchers from drawing [... want %more?] → https://www.contagionlive.com/view/medical-masks-or-n95s-for-covid-19-protection-in-health-care-15:43
BrainstormNew from r/COVID19: COVID19: Higher COVID-19 Vaccination Rates Are Associated with Lower COVID-19 Mortality: A Global Analysis → https://old.reddit.com/r/COVID19/comments/101e5bn/higher_covid19_vaccination_rates_are_associated/16:02
BrainstormUpdates for Iran: +96 cases, +5 deaths since a day ago16:07
BrainstormNew from COVID on Twitter: Prof. Akiko Iwasaki (@VirusesImmunity): A very important and informative thread about why the Omicron XBB.1.5 subvariant is now dominating in the Northeast US and is expected to spread. Please protect yourselves and others by wearing N95 masks. I am truly concerned about the [... want %more?] → https://twitter.com/VirusesImmunity/status/160992834955140301016:12
de-factohttps://covid.cdc.gov/covid-data-tracker/#variant-proportions16:28
de-factohttps://www.nyc.gov/site/doh/covid/covid-19-data-variants.page16:33
de-factohttps://www.nyc.gov/site/doh/covid/covid-19-data-totals.page16:35
de-factohttps://covid.cdc.gov/covid-data-tracker/#wastewater-surveillance16:44
de-factohttps://mbcolli.shinyapps.io/SARS2EWSP/#16:44
de-factohttps://biobot.io/data/17:08
de-factoLjL, ^^17:12
LjLde-facto: complete decoupling from recorded cases, as suspected...17:19
de-factohttps://coronadashboard.rijksoverheid.nl/landelijk/rioolwater <-- this is the dutch sewer sampling17:20
de-factoi wonder how accurate that metric really correlates with number of currently infected17:20
de-factofor the sewer metric to be somewhat accurate we would have to assume 1) viral shedding per infected person roughly is similar, yet it may sharply depend on immuno-competence, age group and variant in question17:21
de-facto2) that the data of RNA copies per ml sewer sample is somehow normalized, e.g. that they account for variable additional water influx etc (possibly by normalizing the data by some other sample that originates from human bodies and roughly remains the same, e.g. some E.coli or whatever)17:22
LjLWell it was very easy to overlay to the "actual" case graph for a period17:26
LjLIt wasn't at the beginning, but we know at the beginning PCR tests were a scarce resource17:26
LjLAnd it isn't now17:27
LjLBut in the middle, it overlapped pretty well17:27
de-factoah you mean there was strong correlation between sewer sampling and antigenic or molecular testing in the mid of the pandemic phase?17:27
LjLBiobot has been doing this for a while, I kind of assume they know what they're doing17:27
LjLI don't know about the NL17:27
LjLI applaud them for doing in the first place since we don't17:27
LjLYes17:28
de-factoyes it makes a lot of sense to do this17:28
de-factomy guess would bet hat hospitalizations wont peak, but i am not so sure about prevalence for people that suffer from long COVID after this wave17:28
de-factothe biobot data is copies / mL of sewage17:30
de-factowhich is fine, yet id like to see a control marker for the concentration of the sewer sample, e.g. above mentioned E.coli DNA copies or similar (for which we could assume a roughly constant shedding rate per participant)17:31
LjLAsking for a friend (really): what's the current take around here over using aspirin not just as pain relief but as potential help with COVID risks? Because I would take it, because I got convinced it helps, but I am aware there were also studies or allegations or anecdotes that it made it *worse* instead, and I don't know if the latter were obsoleted by the former, or it just depends who you ask, or what. Anyway I just wanted to get the feel of the channel about17:40
LjLit... And studies about it if you have some17:40
BrainstormNew from COVID on Twitter: Eric Topol (@EricTopol): New @NatureMedicineProof that Covid vaccines do reduce Omicron transmission from prison data, but the impact is ~20-40% nature.com/articles/s4159… → https://twitter.com/EricTopol/status/160996063666205900818:19
LjLPrison is a very unnatural environment though18:20
de-factoPrison can have a set of very constant contact rate and transmission scenarios, IF they did not change those circumstances during the period of data collection18:27
BrainstormNew from COVID on Twitter: Eric Topol (@EricTopol): Comparative effectiveness of Pfizer vs Moderna booster shot in US Delta and Omicron waves via large @DeptVetAffairs experiencenature.com/articles/s4156…Significant less symptomatic infections and hospitalizations among those treated with Moderna@NatureMicrobiol [... want %more?] → https://twitter.com/EricTopol/status/160996552082840371318:38
BrainstormUpdates for South Korea: +81056 cases, +29 deaths since 17 hours ago19:01
BrainstormNew from COVID on Twitter: Michael Lin, MD PhD   (@michaelzlin): Second, a link to the COVID-19 metathread of 2022twitter.com/michaelzlin/st… → https://twitter.com/michaelzlin/status/160997767629887897619:26
BrainstormNew from COVID on Twitter: Bloom Lab (@jbloom_lab): And as @yunlong_cao nicely describes, this is exactly what is directly measured: twitter.com/yunlong_cao/st… So it’s greater ACE2 affinity (and perhaps RBD stability) that is giving XBB.1.5 its boost in transmissibility, and causing it to surge. → https://twitter.com/jbloom_lab/status/161000280597214412821:03
BrainstormUpdates for Lebanon: +397 cases, +1 deaths since 3 days ago21:06
BrainstormNew from COVID on Twitter: Bloom Lab (@jbloom_lab): By the way, whether increase in fraction of cases due to XBB.1.5 will lead to surge in absolute number of cases is still not certain.But sometimes new variants drive increase in total cases, & in general human coronaviruses (& other respiratory viruses) surge in [... want %more?] → https://twitter.com/jbloom_lab/status/161000758374996787221:22
BrainstormUpdates for France: +39087 cases, +252 deaths since 3 days ago22:08
BrainstormNew from Reddit (test): CoronaVirus_2019_nCoV: Higher COVID-19 Vaccination Rates Are Associated with Lower COVID-19 Mortality: A Global Analysis → https://old.reddit.com/r/CoronaVirus_2019_nCoV/comments/101nmrm/higher_covid19_vaccination_rates_are_associated/22:29
TuvixLjL: Not on point with COVID, but I presume the individual is aware that a recommendation changed recently regarding asprin as a heart-attack reduction; it's no longer recommended "in general" now, only in specific cases where benefits outweigh the risks22:38
TuvixWhile that's not COVID-specific, it also seems to highlight that taking it as a generic preventative actually carries some risks. Presumably those risks remain, but then the question is 1) is there any SARS-CoV-2 benefit, and 2) is that worth the asprin dosage risks the non-COVID findings show.22:39
Tuvix(and sorry, I have no current info on #1 ;)22:40
BrainstormUpdates for Canada: +457 cases since a day ago23:10

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