| Brainstorm | New from Eric Topol on Mastodon: (news): First evidence indicating the JN.1 variant (and BA.2.86) are linked to higher fecal shedding than prior SARSCoV2 variants → https://mstdn.social/@erictopol/112136481190617005 | 01:32 |
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| Brainstorm | New from Reddit (test): COVID19_Pandemic: Severe lung infection during COVID-19 can cause damage to the heart | NIH.gov → https://old.reddit.com/r/COVID19_Pandemic/comments/1bkq3cy/severe_lung_infection_during_covid19_can_cause/ | 06:12 |
| Brainstorm | New from Science-Based Medicine: Some Doctors Cared Much More About Sore Arms Than Cold Bodies: The campaign against boosters was just a small part of a pathetic, pandemic-long pattern where doctors expressed grave concern about the mildest harms of measures to limit COVID, even purely theoretical ones, while being totally [... want %more?] → https://sciencebasedmedicine.org/coldbody/ | 08:09 |
| Brainstorm | New from ProPublica: A Marijuana Boom Led Her to Oklahoma. Then Anti-Drug Agents Seized Her Money and Raided Her Home.: by Clifton Adcock and Garrett Yalch , The Frontier, and Sebastian Rotella and Kirsten Berg , ProPublica This article was produced for ProPublica in partnership [... want %more?] → https://www.propublica.org/article/marijuana-oklahoma-chinese-immigrant-arrests-asset-seizure-2 | 10:48 |
| Brainstorm | New from PubMed: Bryan D Kraft: Use of Inhaled Epoprostenol in Patients With COVID-19 Receiving Humidified, High-Flow Nasal Oxygen Is Associated With Progressive Respiratory Failure → https://pubmed.ncbi.nlm.nih.gov/38516615/ | 11:47 |
| Brainstorm | New from EMA: News and press releases: Meeting highlights from the Committee for Medicinal Products for Human Use (CHMP) 18-21 March 2024: 12 new medicines recommended for approvalEMA’s human medicines committee (CHMP) recommended 12 medicines for approval at [... want %more?] → https://www.ema.europa.eu/en/news/meeting-highlights-committee-medicinal-products-human-use-chmp-18-21-march-2024 | 12:06 |
| Brainstorm | New from Contagion Live: us: The Role of Moderna's Modified mRNA-1273.214 Vaccine in Children Against COVID-19 → https://www.contagionlive.com/view/the-role-of-moderna-s-modified-mrna-1273-214-vaccine-in-children-against-covid-19 | 13:36 |
| Brainstorm | New from r/Science: science: Study shows middle-aged Americans are lonelier than European peers. Contrary to some claims, middle-aged Americans might not be experiencing an epidemic of loneliness. New research suggests that for adults aged 45–65, loneliness might instead be [... want %more?] → https://old.reddit.com/r/science/comments/1bky3kg/study_shows_middleaged_americans_are_lonelier/ | 13:46 |
| Brainstorm | New from Contagion Live: Top 5 Infectious Disease Stories Week of March 16: This week learn more about CDC's strategies to reduce waterborne diseases; the US change to a trivalent influenza vaccine; new data for Merck's pneumococcal vaccine; and how PCR testing can influence a patient [... want %more?] → https://www.contagionlive.com/view/top-5-infectious-disease-stories-week-of-march-16 | 15:16 |
| Brainstorm | New from r/Coronavirus: Coronavirus: Is It Time for an Updated COVID Shot? → https://old.reddit.com/r/Coronavirus/comments/1bl0clm/is_it_time_for_an_updated_covid_shot/ | 15:26 |
| Brainstorm | New from CIDRAP: Scientists caution about CDC guidance on over-the-counter drugs for COVID-19: The investigators conclude that the decision to take acetaminophen, aspirin, or ibuprofen should be done on an individual basis under the guidance of a clinician. → https://www.cidrap.umn.edu/covid-19/scientists-caution-about-cdc-guidance-over-counter-drugs-covid-19 | 17:06 |
| Brainstorm | New from WebMD: An Action Plan for Cold or Flu + COVID-19: It’s possible to catch COVID-19 and a cold or flu at the same time. Here are tips on how to feel better with a coinfection. → https://symptoms.webmd.com/cold-and-flu/cold-flu-map/features/cold-flu-plus-covid | 18:36 |
| Brainstorm | New from CIDRAP: Study finds bivalent COVID vaccine not tied to stroke risk: A high-dose or adjuvanted influenza vaccine was associated with an elevated risk of stroke. → https://www.cidrap.umn.edu/covid-19/study-finds-bivalent-covid-vaccine-not-tied-stroke-risk | 19:45 |
| Brainstorm | New from CIDRAP: New neurologic issues less likely after severe COVID than flu, research suggests: The study didn't specifically examine long-COVID outcomes, and the findings don't necessarily conflict with those of previous studies, the authors say. → https://www.cidrap.umn.edu/covid-19/new-neurologic-issues-less-likely-after-severe-covid-flu-research-suggests | 20:04 |
| Brainstorm | New from Reddit (test): COVID19_Pandemic: Research offers hope for preventing post-COVID ‘brain fog’ by targeting brain’s blood vessels | UIC today → https://old.reddit.com/r/COVID19_Pandemic/comments/1bl7hls/research_offers_hope_for_preventing_postcovid/ | 20:43 |
| Brainstorm | New from CIDRAP: (news): New data show Paxlovid outperforms molnupiravir against severe COVID-19 outcomes → https://www.cidrap.umn.edu/covid-19/new-data-show-paxlovid-outperforms-molnupiravir-against-severe-covid-19-outcomes | 21:51 |
| LjL | de-facto, you are vindicated about molnupiravir, at least efficacy-wise, https://www.cidrap.umn.edu/covid-19/new-data-show-paxlovid-outperforms-molnupiravir-against-severe-covid-19-outcomes although it also seems important that "No significant benefit was found for oral antivirals prescribed beyond 5 days of confirmed infection, the authors said." (honestly I'd have guessed Paxlovid would work after 5 days, it was just the conditions they used for the trial) | 22:06 |
| Brainstorm | New from CIDRAP: (news): US flu activity declines, along with other respiratory viruses → https://www.cidrap.umn.edu/influenza-general/us-flu-activity-declines-along-other-respiratory-viruses | 22:11 |
| de-facto | LjL, it probably does still work, but the question if about the portion of its contribution to over all sink rate for the virions, e.g. if at some point the immune system becomes much more efficient in dealing with the virions even if it not fully developed the neutralizing immune response | 22:27 |
| de-facto | e.g. at some point it may (actually is) more important to attenuate the immune response to prevent associated collateral damage | 22:27 |
| de-facto | but antivirals work immediately, e.g. when given early on may help to give the immune system an edge on time when antivirals reduce the virions reproduction number at cellular level (when there yet are not much immune capabilities deployed against the virions) | 22:29 |
| Brainstorm | New from StatNews: FDA approves new drug to protect immune compromised from Covid-19: Immunocompromised people get a new drug to protect against Covid-19 for the first time since the Omicron variants forced another drug off the market. → https://www.statnews.com/2024/03/22/covid-immunocompromised-antibody-protection-invivyd/ | 23:00 |
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