libera/##covid-19/ Tuesday, 2023-11-28

BrainstormNew from Marc Veldhoen on Mastodon: (news): As used for this trial, symptom alleviation will supplant historical primary endpoints used in studies earlier in the pandemic examining early antiviral interventions to prevent progression from COVID-19. After all, this is the salient endpoint of antivirals for influenza. → https://mastodon.online/@marc_veld/11148508246146685000:26
BrainstormNew from r/COVID19: COVID19: Former HHS assistant secretary Bob Kadlec admits conspiring with Anthony Fauci to downplay COVID lab-leak theory. “I wake up at usually about 2 or 3am and think about it honestly, because it’s something that we all played a role in,” Dr [... want %more?] → https://old.reddit.com/r/COVID19/comments/185hyat/former_hhs_assistant_secretary_bob_kadlec_admits/01:04
BrainstormNew from r/Coronavirus: Coronavirus: Scientists discover receptor that blocks COVID-19 infection → https://old.reddit.com/r/Coronavirus/comments/185mi9f/scientists_discover_receptor_that_blocks_covid19/05:45
BrainstormNew from r/WorldNews: worldnews: China Sees Surge In Mysterious Pneumonia Cases Echoing Early Days of COVID Pandemic → https://old.reddit.com/r/worldnews/comments/185pium/china_sees_surge_in_mysterious_pneumonia_cases/08:01
BrainstormNew from Politico: All the times top official Jenny Harries told Brits to chill about COVID-19: The UK Health Security Agency boss — whose early pandemic interventions raised eyebrows in Westminster — faces the coronavirus inquiry Tuesday. → https://www.politico.eu/article/top-uk-official-jenny-harries-told-britain-chill-covid-19/10:57
BrainstormNew from PubMed: Physical and mental health of informal caregivers before and during the COVID-19 pandemic in the United States: CONCLUSIONS: This study contends that the physical and mental health burden associated with informal caregiving in a period of great uncertainty may be heightened among certain populations. Policymakers [... want %more?] → https://pubmed.ncbi.nlm.nih.gov/38012592/11:07
BrainstormNew from StatNews: STAT+: Argenx antibody fails study in platelet-destroying autoimmune disorder, derailing expansion plans: Belgium drugmaker Argenx said Tuesday that its antibody medicine failed to achieve the goals of a late-stage study for a platelet-destroying [... want %more?] → https://www.statnews.com/2023/11/28/argenx-antibody-fails-study-in-platelet-destroying-autoimmune-disorder/12:25
BrainstormNew from Marc Veldhoen on Mastodon: (news): It is not clear how many reinfections are classed within primary infections, the effect of Delta is a more pathogenic variant. Individual susceptibility may play a role, with immunity from infection or vaccination generally reducing the risk of PASC → https://mastodon.online/@marc_veld/11148794079020797812:36
BrainstormNew from r/Science: science: COVID-19 caused an alarming surge in premature births, but vaccines halted this trend and were key to returning the early birth rate to pre-pandemic levels, according to a new study. In zip codes with the highest vaccination rates, the excess risk [... want %more?] → https://old.reddit.com/r/science/comments/185u546/covid19_caused_an_alarming_surge_in_premature/13:05
BrainstormNew from Politico: Coronavirus: UK’s Michael Gove floats idea COVID ‘man made’ as he defends pandemic response → https://www.politico.eu/article/uks-michael-gove-floats-idea-covid-man-made-as-he-defends-pandemic-response/13:25
BrainstormNew from Politico: Aid and development: Dominic Cummings said UK officials ‘should be shot’ over bungled COVID response → https://www.politico.eu/article/dominic-cummings-said-uk-officials-should-be-shot-over-bungled-covid-response/14:35
BrainstormNew from Marc Veldhoen on Mastodon: (news): The findings similarly support a beneficial effect of vaccination in severing the association between infection exposure and infant health outcomes by using local area-level vaccination rates as a proxy for individual-level vaccination status. → https://mastodon.online/@marc_veld/11148845275328768414:45
BrainstormNew from Contagion Live: Merck's Adult Pneumococcal Vaccine Demonstrates ‘Superior Immunogencity’: Topline data results from the company’s phase 3 trial, STRIDE-3, were announced and will be presented at the World Vaccine Congress West Coast. → https://www.contagionlive.com/view/merck-s-adult-pneumococcal-vaccine-demonstrates-superior-immunogencity-15:26
BrainstormNew from BBC Health: (news): Covid inquiry: Michael Gove defends Boris Johnson over lockdown decision-making → https://www.bbc.co.uk/news/uk-politics-6755747716:56
BrainstormNew from Marc Veldhoen on Mastodon: (news): SARS-CoV-2 is a challenging virus, but due to the protections we've developed, it's as manageable as influenza or RSV. Presenting the facts doesn't categorize us as scaremongers or minimalists; it allows us to elucidate the principles underlying the facts and the reality. → https://mastodon.online/@marc_veld/11148911193693115417:36
BrainstormNew from The Lancet (Online): [Lecture] Success from the South: the rotavirus vaccine story and its lessons: Vaccine equity has been at the forefront of print, television, and social media during the COVID-19 pandemic. Science, technology, and manufacturing brought the world multiple [... want %more?] → https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(23)02520-5/fulltext18:06
BrainstormNew from Eric Topol on Mastodon: (news): Some good news, folks, on the booster (XBB.1.5). It induces robust levels of neutralizing antibodies vs JN.1 → https://mstdn.social/@erictopol/11148947773878645019:04
BrainstormNew from Eric Topol on Mastodon: (news): "While immunological imprinting was still evident with the updated vaccines, it was not nearly as severe as the previously authorized bivalent BA.5 vaccine. Our findings strongly support → https://mstdn.social/@erictopol/11148955620812519219:24
BrainstormNew from r/COVID19: COVID19: XBB.1.5 monovalent mRNA vaccine booster elicits robust neutralizing antibodies against emerging SARS-CoV-2 variants → https://old.reddit.com/r/COVID19/comments/1864gxa/xbb15_monovalent_mrna_vaccine_booster_elicits/20:33
BrainstormNew from Reddit (test): Covid2019: After three years, I finally got it → https://old.reddit.com/r/Covid2019/comments/1865217/after_three_years_i_finally_got_it/21:03
BrainstormNew from r/Coronavirus: Coronavirus: Study: Air purifier use at daycare centres cut kids' sick days by a third. The results of the study at two Helsinki daycare centres are still preliminary but promising, a researcher says. → https://old.reddit.com/r/Coronavirus/comments/1866950/study_air_purifier_use_at_daycare_centres_cut/21:58
de-facto%title https://medicalxpress.com/news/2023-11-covid-variant-states.html23:30
Brainstormde-facto: From medicalxpress.com: New COVID variant takes hold in the United States23:30
de-facto%title https://covid.cdc.gov/covid-data-tracker/#variant-proportions23:34
Brainstormde-facto: From covid.cdc.gov: CDC COVID Data Tracker23:34
de-factoLjL, seems HV.1 really is on the rise in USA since August or such23:35
de-factoaka XBB.1.9.2.5.1.6.1 https://outbreak.info/situation-reports?xmin=2023-05-28&xmax=2023-11-28&pango=HV.123:42
de-factoreally on increase globally23:42
de-factoLjL, have you heard of that one before?23:42
de-factohttps://cov-spectrum.org/explore/World/AllSamples/Past6M/variants?nextcladePangoLineage=hv.1&23:46
Brainstorm(Matrix) <L​jL> I've heard of it, but that's about it23:48
de-factoits seems to be constantly rising23:49
de-factoi mean that is what every new (potentially relevant) variant does, idk anything about its properties other than it appears on the sequencing radars globally increasing23:49
de-factoproportion on sequences 2023-09-01 2.09% -> 2023-11-01 16.62% means 7.95-fold in 61 days23:54

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