libera/##covid-19/ Wednesday, 2023-05-03

BrainstormNew from COVID on Twitter: Eric Topol (@EricTopol): The implication of this mRNA design advance includes more efficacious and durable vaccines and, beyond that:  "can be used for all therapeutic proteins including monoclonal antibodies and anti-cancer drugs."[BTW zoster not foster] → https://twitter.com/EricTopol/status/165351963493782732800:05
BrainstormNew from Reddit (test): CoronaVirus_2019_nCoV: Long Covid, Awakenings, and the enigma of post-viral illness: long Covid patients are all too easy to ignore: often housebound, bedbound, and out of sight A tragic reminder of a pandemic the rest of society is [... want %more?] → https://old.reddit.com/r/CoronaVirus_2019_nCoV/comments/1361y6a/long_covid_awakenings_and_the_enigma_of_postviral/00:15
BrainstormNew from r/COVID19: COVID19: Repeated Omicron infection alleviates SARS-CoV-2 immune imprinting → https://old.reddit.com/r/COVID19/comments/1363aas/repeated_omicron_infection_alleviates_sarscov2/01:03
BrainstormNew from r/Science: science: More children and adolescents in mental health crisis since beginning of COVID-19 pandemic: study → https://old.reddit.com/r/science/comments/1363xhv/more_children_and_adolescents_in_mental_health/02:20
BrainstormNew from Outbreak News Today: Brazil: Paraná state dengue update: NewsDesk @bactiman63 The new epidemiological bulletin from the State Department of Health (Sesa) released today confirms 6,889 new cases and six deaths from dengue compared to the previous week’s report. To date, Paraná has registered [... want %more?] → http://outbreaknewstoday.com/brazil-parana-state-dengue-update-51392/04:35
BrainstormNew from r/Coronavirus: Coronavirus: Health Board ends pandemic phase, returns to normal service → https://old.reddit.com/r/Coronavirus/comments/136c9d6/health_board_ends_pandemic_phase_returns_to/08:47
BrainstormNew from r/Coronavirus: Daily Discussion Thread | May 03, 2023: Please refer to our Wiki for more information on COVID-19 and our sub. You can find answers to frequently asked questions in our FAQ , where there is valuable information such as our: → https://old.reddit.com/r/Coronavirus/comments/136d2af/daily_discussion_thread_may_03_2023/09:08
BrainstormNew from COVID on Twitter: Tom Wenseleers (@TWenseleers): Or rather: the 11% share figure for XBB.1.16 should have been attributed to the CDC nowcast, covid.cdc.gov/covid-data-tra…, which was for the week ending 29th of April 2023. My figure of ca 50% share, raw.githubusercontent.com/tomwenseleers/…, was for [... want %more?] → https://twitter.com/TWenseleers/status/165367631536558899210:26
BrainstormNew from r/COVID19: COVID19: The covid-19 virus affects our gut – but we still don’t know how → https://old.reddit.com/r/COVID19/comments/136f38j/the_covid19_virus_affects_our_gut_but_we_still/11:07
BrainstormNew from r/COVID19: COVID19: Survival of SARS-CoV-2 in wastewater → https://old.reddit.com/r/COVID19/comments/136fu1c/survival_of_sarscov2_in_wastewater/11:47
BrainstormNew from COVID on Twitter: Scott Gottlieb, MD (@ScottGottliebMD): Most likely transmission dynamic for covid may be cycles of “wavelets” — ‘While flu and common-cold coronaviruses cause seasonal epidemics, the combo of rapid mutation, shorter-lived immunity may prevent covid from settling into seasonal [... want %more?] → https://twitter.com/ScottGottliebMD/status/165369897272735744311:56
BrainstormNew from ProPublica: What You Need to Know About Stillbirths: by Adriana Gallardo and Duaa Eldeib ProPublica is a nonprofit newsroom that investigates abuses of power. Sign up to receive our biggest stories as soon as they’re published. Every year, more than 20,000 pregnancies in the U.S. end in a [... want %more?] → https://www.propublica.org/article/what-to-know-about-stillbirths12:07
-Bridgestorm- ⭕ 地震! Earthquake! 6.3 Mb tremor, registered by scevent, occurred 18 minutes ago (09:56:19 UTC), during daytime, on land, Aba, China (32.4, 101.53), ↓100 km likely felt 550 km away (in 马尔康市, 班玛县…) by 65400 people - important: https://twitter.com/BrainstormBot/status/1643764418075938817 (service.geonet.org.nz)12:14
BrainstormNew from Reddit (test): nCoV: One man's thoughts on the topic of being confounded by social circumstances. → https://old.reddit.com/r/nCoV/comments/136gfn5/one_mans_thoughts_on_the_topic_of_being/12:26
BrainstormNew from r/COVID19: COVID19: The value of lung ultrasound in COVID-19 pneumonia, verified by high resolution computed tomography assessed by artificial intelligence → https://old.reddit.com/r/COVID19/comments/136igio/the_value_of_lung_ultrasound_in_covid19_pneumonia/14:05
BrainstormNew from COVID on Twitter: Gunhild Alvik Nyborg (@GANyborg): Many studies incl. animal studies show causal links between #LongCovid symptoms and SARS2’ presence in different organ systems@PutrinoLab’s       encourages “clinicians to rethink their biases and update their clinical approaches in the presence of [... want %more?] → https://twitter.com/GANyborg/status/165374483669073101515:05
BrainstormNew from COVID on Twitter: Dr Emma Hodcroft (@firefoxx66): One of the ways you might have seen #UShER in the pandemic may have been for @PangoNetwork lineage proposals! They are a common feature of new lineage issues as a way to visualise how they branch from other lineages & what mutations they harbour! (And [... want %more?] → https://twitter.com/firefoxx66/status/165375115676034662615:24
BrainstormNew from COVID on Twitter: In the Bubble (@inthebubblepod): .@EricTopol returns to break down who should get boosted, who should get a second booster, and who can wait a bit. Eric also discusses his thoughts on where we are in the fight against COVID and what the next frontier of vaccines will look [... want %more?] → https://twitter.com/inthebubblepod/status/165375234325337702515:44
BrainstormNew from ClinicalTrials.gov: (news): Immunoadsorption Study Mainz in Adults With Post-COVID Syndrome → https://clinicaltrials.gov/ct2/show/NCT0584149817:32
BrainstormNew from ClinicalTrials.gov: (news): A Study in Healthy Volunteers to Evaluate the Safety, Tolerability, Pharmacokinetics, and Drug-Drug Interaction Potential of Single and Multiple Doses of ALG-097558 → https://clinicaltrials.gov/ct2/show/NCT0584095217:42
BrainstormNew from ClinicalTrials.gov: Quality of Nursing Care During The Covid-19 Pandemic: Conditions :    COVID-19 Pandemic;   Children, Only;   Hospitalism;   Nurse's Role;   Feelings → https://clinicaltrials.gov/ct2/show/NCT0584160218:02
BrainstormNew from ClinicalTrials.gov: (news): Working Towards Empowered Community-driven Approaches to Increase Vaccination and Preventive Care Engagement → https://clinicaltrials.gov/ct2/show/NCT0584181018:11
BrainstormNew from COVID on Twitter: Eric Topol (@EricTopol): A systematic review of vaccine protection vs Omicron (and Delta) Covid infections shows substantial waning after 3 months, reduced with a booster@JAMANetworkOpen jamanetwork.com/journals/jaman… pic.twitter.com/g8k4qMJfL2 → https://twitter.com/EricTopol/status/165379787769577881718:31
BrainstormNew from Contagion Live: Symptom and Viral Rebound in Untreated COVID-19 Patients: COVID-19 symptom or viral rebound in the absence of antiviral treatment is common, but the combination of symptom and viral relapse is rare. → https://www.contagionlive.com/view/symptom-and-viral-rebound-in-untreated-covid-19-patients18:51
BrainstormNew from StatNews: FDA approves first RSV vaccine, a long-sought scientific achievement: The FDA has approved the first-ever vaccine for respiratory syncytial virus, or RSV, completing an elusive quest that has been decades in the making. → https://www.statnews.com/2023/05/03/fda-approves-rsv-vaccine-gsk/19:10
BrainstormNew from COVID on Twitter: The Washington Post (@washingtonpost): U.S. regulators Wednesday approved the first vaccine to prevent the respiratory ailment RSV, a decision that marks a turning point in the six-decade-long quest to protect vulnerable people against the virus. wapo.st/422ItLn → https://twitter.com/washingtonpost/status/165381948026954956919:59
BrainstormNew from Il Sole 24 Ore: (translated) WHO ready to declare the end of the pandemic after 7 million deaths: "Now the virus is in small waves": The fifteenth meeting of the Emergency Committee for Covid-19 is held which could represent a decisive step towards [... want %more?] → https://www.ilsole24ore.com/art/oms-pronta-dichiarare-fine-pandemia-7-milioni-morti-ora-virus-piccole-onde-AE46eHPD20:09
BrainstormNew from Contagion Live: FDA Approves GSK’s Arexvy as the World’s First RSV Vaccine for Older Adults: The FDA has authorized GSK’s Arexvy (RSVPreF3 +AS01E) prevent lower respiratory tract disease (LRTD) caused by RSV in adults 60 years and older. → https://www.contagionlive.com/view/fda-approves-gsk-s-arexvy-as-the-world-s-first-rsv-vaccine-for-older-adults20:29
BrainstormNew from COVID on Twitter: Michael Lin, MD PhD   (@michaelzlin): The first RSV vax was approved today. It is the RSV fusion protein (analogous to coronavirus spike) mutated to be stabilized in the prefusion configuration, with an adjuvant.If this sounds familiar it is because it is similar to Novavaxcnn.com/2023/05/03/hea… → https://twitter.com/michaelzlin/status/165383523754852352020:58
BrainstormNew from COVID on Twitter: Michael Lin, MD PhD   (@michaelzlin): RSV is infamous because a RSV vaccine made from chemically inactivated viruses ended up making the disease worse through antibody-dependent enhancement (ADE). Turns out the chemical treatment fixed the fusion protein in a non-native form. → https://twitter.com/michaelzlin/status/165383523929754009721:08
BrainstormNew from COVID on Twitter: Michael Lin, MD PhD   (@michaelzlin): GSK's vax was in development from before SARSCoV2. Subunit vax were established with HBV in the 1980s, but the prefusion stabilization mutations were found in the 2010s.  Quite likely SARSCoV2 vax approaches were informed by the RSV work on [... want %more?] → https://twitter.com/michaelzlin/status/165383866082619801621:18
BrainstormNew from ScienceNews: The FDA has approved the first-ever vaccine for RSV: GSK’s shot, for those 60 and over, can protect against severe respiratory syncytial virus. Other vaccines, including to protect newborns, are in the works. → https://www.sciencenews.org/article/fda-approved-first-vaccine-rsv21:58
BrainstormNew from COVID on Twitter: Michael Lin, MD PhD   (@michaelzlin): Today's approval is for GSKs vaccine for adults 65yo and older. RSV leads to 10k deaths a year in this population, so about a quarter to a half of flu. The field is still open for a vaccine for young kids or expecting moms. → https://twitter.com/michaelzlin/status/165385250711708876822:08
BrainstormNew from r/Coronavirus: Coronavirus: More children and adolescents in mental health crisis since beginning of COVID-19 pandemic: study → https://old.reddit.com/r/Coronavirus/comments/136yphf/more_children_and_adolescents_in_mental_health/22:38
BrainstormNew from StatNews: STAT+: What the Covid-19 pandemic can teach us about drug patents: “Thirty years after the HIV epidemic, why is there still a time lag of years to get medical products to different regions in the world?” #Breakthrough23 → https://www.statnews.com/2023/05/03/covid-19-drug-patents/23:07

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