libera/##covid-19/ Thursday, 2023-04-13

BrainstormUpdates for Cuba: +17 cases since a day ago — Sri Lanka: +3 cases since a day ago00:11
BrainstormNew from Reddit (test): CoronavirusUK: Three Years Later, Covid-19 Is Still a Health Threat. Journalism Needs to Reflect That → https://old.reddit.com/r/CoronavirusUK/comments/12k1ize/three_years_later_covid19_is_still_a_health/00:22
BrainstormNew from The Lancet (Online): [Articles] Higher dose corticosteroids in patients admitted to hospital with COVID-19 who are hypoxic but not requiring ventilatory support (RECOVERY): a randomised, controlled, open-label, platform trial: In patients hospitalised for COVID-19 with clinical [... want %more?] → https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(23)00510-X/fulltext00:31
BrainstormNew from BBC Health: (news): Ghana first to approve 'world-changer' malaria vaccine → https://www.bbc.co.uk/news/health-6525251101:29
BrainstormNew from BBC Health: Covid: Staff propped up care homes without extra pay, says report: Most care homes struggled but some paid more to shareholders, says the Warwick University-led study. → https://www.bbc.co.uk/news/uk-6525054602:22
BrainstormUpdates for UAE: +1167 cases, +104088 tests since 5 days ago — Guatemala: +221 cases, +6579 tests since a day ago — Norway: +110 cases since a day ago04:01
BrainstormUpdates for Eswatini: +197 cases since a month ago05:04
BrainstormUpdates for Peru: +690 cases, +38 deaths since a day ago — Germany: +3346 cases, +151 deaths since a day ago06:06
BrainstormNew from r/Coronavirus: Daily Discussion Thread | April 13, 2023: Please refer to our Wiki for more information on COVID-19 and our sub. You can find answers to frequently asked questions in our FAQ , where there is valuable information such as our: → https://old.reddit.com/r/Coronavirus/comments/12kfft8/daily_discussion_thread_april_13_2023/09:03
BrainstormNew from Reddit (test): CoronaVirus_2019_nCoV: COVID-19 and Your Heart: Call your doctor or go to the ER right away if you have any of the following after you’ve recovered from COVID: Tiredness Trouble breathing Swelling Pain in your chest If any of those [... want %more?] → https://old.reddit.com/r/CoronaVirus_2019_nCoV/comments/12kgc31/covid19_and_your_heart_call_your_doctor_or_go_to/09:44
BrainstormNew from r/COVID19: COVID19: Waning of humoral immunity depending on the types of COVID-19 vaccine → https://old.reddit.com/r/COVID19/comments/12kiwdv/waning_of_humoral_immunity_depending_on_the_types/11:37
BrainstormNew from Reddit (test): nCoV: Global COVID Cases For 13APR23 → https://old.reddit.com/r/nCoV/comments/12kjlq9/global_covid_cases_for_13apr23/12:08
BrainstormNew from r/COVID19: COVID19: Admission and follow-up cardiac magnetic resonance imaging findings in BNT162b2 Vaccine-Related myocarditis in adolescents → https://old.reddit.com/r/COVID19/comments/12kky78/admission_and_followup_cardiac_magnetic_resonance/13:00
BrainstormUpdates for India: +10158 cases, +19 deaths, +214242 tests since a day ago — Canada: +7024 cases, +126 deaths since 8 days ago13:04
BrainstormNew from r/COVID19: COVID19: Cardiac magnetic resonance imaging findings in COVID-19 vaccine-related myocarditis → https://old.reddit.com/r/COVID19/comments/12kkymn/cardiac_magnetic_resonance_imaging_findings_in/13:10
BrainstormNew from BMJ: Covid-19 was the third leading cause of death in Australia last year: Covid-19 became Australia’s third leading cause of death in 2022, after ischaemic heart disease and dementia, according to an analysis.1There were 20 200 more deaths in 2022 than would have been expected if the pandemic had not happened, with [... want %more?] → http://www.bmj.com/content/381/bmj.p842.short14:03
BrainstormNew from r/Coronavirus: Coronavirus: Study notes high rate of COVID-infected healthcare workers still caring for patients → https://old.reddit.com/r/Coronavirus/comments/12kmalq/study_notes_high_rate_of_covidinfected_healthcare/14:34
BrainstormNew from r/COVID19: COVID19: Efficacy of personal protective equipment to prevent environmental infection of COVID-19 among healthcare workers: a systematic review → https://old.reddit.com/r/COVID19/comments/12ko8ex/efficacy_of_personal_protective_equipment_to/15:06
BrainstormUpdates for Russia: +7892 cases, +37 deaths since a day ago15:09
BrainstormNew from COVID on Twitter: Eric Topol (@EricTopol): Beyond autoimmunity as a mechanism for #LongCovid, the heightened risk of autoimmune diseases"Compelling and reliable evidence that #SARSCoV2 infection is linked to a substantially increased risk of developing diverse new-onset autoimmune [... want %more?] → https://twitter.com/EricTopol/status/164650768027264205015:48
BrainstormNew from Reddit (test): nCoV: Case Report | A case of fatal multi-organ inflammation following COVID-19 vaccination | Abstract in comments | 20MAR23 → https://old.reddit.com/r/nCoV/comments/12kpw14/case_report_a_case_of_fatal_multiorgan/15:59
BrainstormNew from COVID on Twitter: Eric Topol (@EricTopol): A T-cell directed vaccine against Covid, with non-spike, conserved antigens (e.g. nucleocapsid, ORF1ab), effective in experimental models for preventing disease, has gone into clinical trials clinicaltrials.gov/ct2/show/NCT05…cell.com/cell/fulltext/… [... want %more?] → https://twitter.com/EricTopol/status/164651299966092492816:10
BrainstormUpdates for Indonesia: +990 cases, +14 deaths since a day ago16:11
BrainstormNew from Il Sole 24 Ore: (translated) Here is the commission of inquiry into Covid:  it will investigate everything, but not the Regions: Pd and M5S did not vote by attacking the center-right. The League aims to exclude Governor Fontana from managing Lombardy → https://www.ilsole24ore.com/art/ecco-commissione-d-inchiesta-covid-indaghera-tutto-ma-non-regioni-AEIfIhGD16:40
BrainstormNew from COVID on Twitter: Marc Veldhoen (@Marc_Veld): And new: responses to other SARS-CoV-2 antigens. pic.twitter.com/Idqr9jkkom → https://twitter.com/Marc_Veld/status/164652681871820390417:01
BrainstormUpdates for Austria: +1706 cases, +11 deaths since a day ago — Hong Kong: +196 cases, +1 deaths since a day ago17:01
BrainstormNew from WebMD: Had COVID? Part of the Virus May Stick Around in Your Brain: Investigators discovered the spike protein from the virus in brain tissue of animals and people after death. The finding suggests these virus fragments build up, stick around, and trigger inflammation that [... want %more?] → https://www.webmd.com/covid/news/20230413/part-of-coronavirus-may-stick-around-the-brain17:53
BrainstormNew from StatNews: Promising new malaria vaccine for kids approved in Ghana: Ghana on Thursday became the first country to approve a new malaria vaccine for young children, one that officials hope will offer better protection against the disease that kills hundreds… → https://www.statnews.com/2023/04/13/malaria-vaccine-kids-approved-ghana/18:56
LjLhmm, that webmd article, and related study, will likely be another "see! the vaccines will cause the same!" weapon for anti-vax people. then again, the article never mentions that, and i'm not sure that's a good idea, as opposed to tackling the problem by mentioning it and explaining why it's unlikely to happen with the vaccine19:03
LjLEric Topol is co-author of a long COVID paper on Nature https://www.nature.com/articles/s41579-022-00846-219:12
LjLreview paper19:12
LjLublx, if you can check backscroll on Matrix, there's a couple of potentially interesting things on long COVID, or else wait for the bot to fetch them from the Zotero feed19:17
ublxah ok19:17
TuvixI haven't yet read the WebMD paper (but am familiar with the high-level of the findings already.) I suspect part of the reason to "skip" that in strictly medical-literature is because mRNA only spurs production of the spike protein, not the virus.19:21
LjLTuvix, well, but it's the spike protein that is being implicated in these findings, not the whole virus (they actually checked that in people who *had* the full virus in their brain, there was no difference compared to those who only had the spike protein)19:23
LjLalso webmd isn't strictly medical literature, it's definitely a platform for popular reading of medical topics19:24
TuvixSure, though IIRC the information is so new that the experts I've heard reviewing the findings report that the results are suggestive that the virus itself ends up in a variety of organs.19:24
ubLIX[m]couple of things: brain viral fragments and the Topol paper?19:24
LjLnot surprised... there have already been solid papers showing the virus stays in the guts, they have just been largely ignored19:24
LjLubLIX[m], yes19:24
LjLnot sure why bot is not posting, i was waiting for it to post the one so that i could post the other too19:25
TuvixThere's talk already of further research needed to identify possible locations and (perhaps more importantly!) the *causes* of possible viral reservoirs19:25
TuvixThe problem is that, while very critical, the recent study & paper really poses more questions for studies to follow than answers.19:25
LjLTuvix, i think the most important thing to ascertain is: how often does it happen? because really, it would be pretty easy (compared to the gargantuan tasks we faced of locking down the world and making billions of vaccines) to sample the stool from a large and representative sample of people and see if there's still virus even when their last infection was long ago19:26
BrainstormNew from Reddit (test): Jab Injuries Global: submitted by /u/IIWIIM8 to r/nCoV → https://old.reddit.com/r/nCoV/comments/12kwg89/jab_injuries_global/19:27
LjLi think the studies we do have should have been a call to action to do that right away, but apparently i think uncommon things19:27
LjLBrainstorm, well that's not even my article, so get lost19:27
BrainstormLjL: people already are 50%-200% (yeah, and it sometimes happens, but I still get infected after those 6 months, I see, they lost all credibility, and had a problem on its own thing19:27
TuvixA big part of the motivation is funding. Many cities around me have stopped what limited wastewater treatment plant reporting they used to be doing.19:28
TuvixWhat you're describing is more targeted, but my point is that if we can't fund high-level analysis at the treatment plants, where's funding for representative sampling going to come from.19:29
LjLi use the tag "Persistence" for articles on Zotero dealing with virus sticking around: https://www.zotero.org/groups/4391070/covid_links/tags/Persistence/library19:30
TuvixSadly, I suspect funding will continue to wane until well after any mutations to a more nasty version of COVID than Omicron's evolution has been so far.19:30
LjLsadly, i concur19:31
TuvixThen everyone will want to know why we didn't see it sooner. Pointing back to today's conversation will have little reward in such a future.19:31
LjLi won't even remember what to point at because i'm just that bad19:32
TuvixIt wouldn't serve a purpose other than a post-mortem by those equipped to do something about it. I'm not the latter so any effort noting it would be wasted.19:33
TuvixIt's not like I'm in a position to campaign for better funding of preventative medical care or sampling projects.19:34
TuvixOver here on this side of the pond, there's always been less focus on prevention and focus on treatment, despite the massive cost savings in prevention-focused healthcare.19:35
Tuvix(more focus on treatment, that is)19:35
BrainstormNew from ##covid-19 Zotero group: Had COVID? Part of the Virus May Stick Around in Your Brain: Item Type Web Page Author Damian McNamara Author MA URL https://www.webmd.com/covid/news/20230413/part-of-coronavirus-may-stick-around-the-brain Accessed 2023-04-13 17:28:50 Language en Abstract Investigators discovered the [... want %more?] → https://www.zotero.org/groups/covid_links/items/UKAKIZ6W19:38
ublxon that side of the pond, aren't healthcare cost savings viewed as cheating some provider/insurer out of profits?19:38
TuvixNot in so many words, but yes. Naturally that viewpoint is hidden behind a bunch of misinformation about "death panels" and similar loaded-terms that are designed to appeal to emotion and not fact.19:42
TuvixAny time there's talk of reducing costs it's not phrased as "CEOs will loose out" (that'd encourage voters to support it) but instead termed a danger because of the loss of control the insurance companies have. In reality of course that control is used to claim exclusions ("page 842 of your policy states…")19:43
TuvixI experienced that personally a couple years ago with some dental care. A 15-minute visit with my surgen to go over a *future* visit was billed to me at around $100 despite it falling into a coding category for assessment which should have been covered 100%, similar to preventative care.19:45
TuvixSadly, I was billed for it because I already had a "consult" visit (same coding, but not with a surgen, just my dental cleaning doctor) and I'm only allowed 1 consult code per 6 months.19:46
ublxwonder how much the dentist would have asked, for a 15 minute, if paid by you directly19:47
TuvixProbably less. I did the math that year and insurance only paid out about what I put in over the whole year.19:48
TuvixIn other words, I'd have been break-even not having *any* insurance at all, and in reality I'd probably have saved several-hundred dollars because many clinics bill no-insurance patience at a lower rate.19:48
TuvixHow's that for irony? Based on my medical needs that year, being "covered" by insurance probably costed me money.19:48
TuvixObviously I didn't know that ahead of time; no one here actually asks a clinic to come up with an itemized list of every medical billing code to ask the insurance company ahead of time what it will cost and then decide if to bill to insurance and/or how else to pay.19:49
TuvixThe claim in the US is that consumers can make "smarter choices" with our system, but theh reality is that's a lie.19:50
ublxcan you ask for direct bills 100% of the time, and only redirect them yourself to the insurer if it's in your interest to do so?19:51
TuvixNo, because you have to actually file a claim to see what the insurance company does.19:51
TuvixBy that point it's too late to play do-over.19:51
ublxhm19:52
TuvixYou can ask for a review from insurance as to *if* it'll be covered, but 1) they aren't bound by that, so can just change their minds later and you have no power to object, or 2) the reality is that you can't know all the itemized procedure codes you'll face on any visit because that depends on how the visit goes.19:52
TuvixYou can see how those 2 items make the whole thing a black-box that consumers have almost no visibility into.19:52
TuvixThat's of course the whole point.19:52
TuvixThere's a weekly radio segment here where a medical billing professional goes over a bill sent in by a listener. Some of the games insurance companies play are quite nasty.19:53
TuvixUsually those cases end up resolved favorably to the customer, but only after *national* radio attention was brought to it :(19:53
ublxfor all the cost disease and black boxery, though, i wonder if your system does better in terms of resource availability; as in, it might be expensive but if it's available in a timely fashion, some outcomes might be better; "timely fashion" can be problematic over here19:54
TuvixMaybe to a point, but beware the other perverse incentive: doing procedures & tests that aren't actually necessary that net the hospitals performing them more proffits.19:56
TuvixThat's a thing too, and it's hard to spot since it's not always obvious, sometimes even to the doctors perscribing the tests.19:56
TuvixSay you have some fancy machine that cost $100 Million, but another test that's far cheaper (considering both insurance and consumer balance for the procedure combined.) Even if the cheaper test is likely just as effective, there's often provider-incentive to use the costly machine to "earn back" its purchase costs.19:57
TuvixAnd if insurance covers it fully or at least most of it, consumers are happy to play along (most not realizing that by insurnace paying for it, we all pay for it as a society.)19:58
TuvixBasically the sunk-cost fallacy. "We paid for the thing, so now we have to use it even if it's not an advantage."19:59
BrainstormNew from StatNews: The Readout LOUD: Listen: How the legal battle over abortion could thwart research, plus: the FDA ‘bully pulpit’ and Moderna’s future → https://www.statnews.com/2023/04/13/podcast-legal-battle-abortion-research-fda-moderna/20:40
LjLi just paid €150 for a filling20:51
TuvixBy contrast you could have paid say €10/mo for dental insurance by US-standards, and then some percentage of the filling (and all other annual non-strict-preventiative care) would be paid out at a percentage varying based on the procedure, usually capped to an annual maximum the insurance will pay out (common in US dental plans) and you'll get a bill for the remainder uncovered amount.20:58
TuvixIf the covered percentage was any less than 80% (billing you for the remaining 20%) that example actually costs you more to have insurance than the sticker-price you gave. Those numbers are not that far off from my last dental plan.20:59
BrainstormNew from COVID on Twitter: Bloom Lab (@jbloom_lab): @bdadonaite & I contributed by using spike-pseudotyped lentiviral deep mutational scanning to comprehensively map escape mutations from antibody 12-19.The key escape mutations are shown below, and see dms-vep.github.io/SARS-CoV-2_Omi… for a full map of escape [... want %more?] → https://twitter.com/jbloom_lab/status/164660364244589363322:02
BrainstormNew from Outbreak News Today: Oxford malaria vaccine licensed for use in Ghana: NewsDesk @bactiman63 The University of Oxford-developed and Serum Institute of India PvT Ltd (SIIPL)- manufactured and scaled up R21/Matrix-MTM malaria vaccine, leveraging Novavax’s adjuvant technology, has [... want %more?] → http://outbreaknewstoday.com/oxford-malaria-vaccine-licensed-for-use-in-ghana-69415/23:00
BrainstormUpdates for Cuba: +19 cases since 22 hours ago23:03

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