libera/##covid-19/ Friday, 2023-03-10

BrainstormUpdates for Canada: +3696 cases since 21 hours ago00:05
BrainstormNew from r/COVID19: COVID19: Autoantibodies against chemokines post-SARS-CoV-2 infection correlate with disease course → https://old.reddit.com/r/COVID19/comments/11n70pl/autoantibodies_against_chemokines_postsarscov2/00:12
BrainstormUpdates for California, United States: +10668 cases since 5 days ago01:07
BrainstormNew from COVID on Twitter: Eric Topol (@EricTopol): 3 years in, the status of #LongCovid Editorial @TheLancet"Progress has been excruciatingly slow due to lack of attention and resources"thelancet.com/journals/lance… pic.twitter.com/fxauyKYAAr → https://twitter.com/EricTopol/status/163398192458173645001:11
BrainstormNew from r/Coronavirus: Coronavirus: No, That New Study Doesn’t Show that Masks Are Useless → https://old.reddit.com/r/Coronavirus/comments/11n9tlb/no_that_new_study_doesnt_show_that_masks_are/02:27
BrainstormUpdates for Australia: +11252 cases, +69 deaths since 6 days ago02:59
BrainstormUpdates for Pakistan: +73 cases since 22 hours ago04:01
BrainstormNew from r/Coronavirus: Coronavirus: 2 lions die of COVID-19 at Japanese zoo → https://old.reddit.com/r/Coronavirus/comments/11nc07p/2_lions_die_of_covid19_at_japanese_zoo/04:04
BrainstormUpdates for United Kingdom: +28783 cases since 22 hours ago05:04
BrainstormUpdates for Belgium: +11570 cases, +39 deaths since 6 days ago — Germany: +7829 cases, +127 deaths since 23 hours ago06:06
BrainstormUpdates for Ontario, Canada: +3250 cases, +48 deaths since a day ago — Moscow, Russia: +2404 cases, +11 deaths since 23 hours ago — East Flanders, Belgium: +2250 cases since 6 days ago — West Flanders, Belgium: +2049 cases since 6 days ago07:02
BrainstormNew from BBC Health: Chinese city Xi'an draws backlash with flu lockdown proposal: Xi'an says it may turn to lockdowns - a measure criticised as "excessive" after strict Covid controls. → https://www.bbc.co.uk/news/world-asia-china-6491121207:08
BrainstormNew from r/Coronavirus: Daily Discussion Thread | March 10, 2023: Please refer to our Wiki for more information on COVID-19 and our sub. You can find answers to frequently asked questions in our FAQ , where there is valuable information such as our: → https://old.reddit.com/r/Coronavirus/comments/11niu4m/daily_discussion_thread_march_10_2023/09:02
BrainstormNew from r/COVID19: COVID19: Acute and Postacute Clinical Characteristics of Coronavirus Disease 2019 in Children in Japan → https://old.reddit.com/r/COVID19/comments/11nj66u/acute_and_postacute_clinical_characteristics_of/09:21
BrainstormNew from r/COVID19: COVID19: Trimeric protein vaccine based on Beta variant elicits robust immune response against BA.4/5-included SARS-CoV-2 Omicron variants → https://old.reddit.com/r/COVID19/comments/11njogb/trimeric_protein_vaccine_based_on_beta_variant/09:51
BrainstormNew from COVID on Twitter: Adam Kucharski (@adamjkucharski): In hindsight, it can be easy to forget that all the parameters we now have for COVID - from incubation period and clinical progression to severity and transmissibility - had to be estimated by someone. A thread on some of the crucial early work in this [... want %more?] → https://twitter.com/adamjkucharski/status/163411460114599936010:10
-Bridgestorm- 🌖 Temblor? Sismo? Earthquake? Maybe strong tremor, registered by alomax, with 72 reports, 17 early, possibly occurred 5 minutes ago (09:18:45 UTC), during a gibbous moon night, Landázuri, Colombia (6.23, -73.84) ± 115 km likely felt 280 km away by 100 people (alomax.free.fr)10:24
-Bridgestorm- 🏠 Temblor! Sismo! Earthquake! 5.6 Mb tremor, registered by alomax, with 87 reports, 15 early, occurred 8 minutes ago (09:18:41 UTC), during a gibbous moon night, El Carmen, Colombia (6.7, -73.48) ± 89 km, ↓72 km likely felt 360 km away (in Bucaramanga, Floridablanca, Barrancabermeja…) by 1.4 million people (alomax.free.fr)10:26
BrainstormNew from StatNews: STAT+: Several years later, AstraZeneca says its drug extends life for some early-stage lung cancers: The main issue with an AstraZeneca drug was whether disease-free survival translated into overall survival for some lung cancer patients. Now the company says it does. → https://www.statnews.com/2023/03/10/astrazeneca-osimertinib-lung-cancer-survival/10:39
BrainstormUpdates for Lithuania: +683 cases, +2 deaths since 2 days ago11:11
BrainstormNew from ProPublica: How to Track Your Tax Refund in 2023: by Kristen Doerer for ProPublica ProPublica is a nonprofit newsroom that investigates abuses of power. Sign up to receive our biggest stories as soon as they’re published. You’ve figured out your deductions or credits, calculated how much you owed [... want %more?] → https://www.propublica.org/article/where-is-my-tax-refund-202311:18
BrainstormNew from EMA: Human medicine assessment reports: (news): Human medicines European public assessment report (EPAR): Ronapreve, casirivimab,imdevimab, COVID-19 virus infection, Date of authorisation: 12/11/2021, Revision: 3, Status: Authorised → https://www.ema.europa.eu/en/medicines/human/EPAR/ronapreve11:38
BrainstormNew from r/Science: science: Gun violence is the top killer of US kids—the pandemic made it worse | Researchers call for firearm policy changes and efforts to address structural racism. → https://old.reddit.com/r/science/comments/11nllx0/gun_violence_is_the_top_killer_of_us_kidsthe/11:48
BrainstormNew from Reddit (test): nCoV: Global COVID Cases For 10MAR23 → https://old.reddit.com/r/nCoV/comments/11nlz6f/global_covid_cases_for_10mar23/12:07
BrainstormNew from BMJ: Strikes, patient outcomes, and the cost of failing to act: Growing demands on healthcare workers have seen them become more vocal about their dissatisfaction with the conditions of the health systems in which they work. In the first year of the covid-19 pandemic, there were at least 6500 protests by [... want %more?] → http://www.bmj.com/content/380/bmj-2022-072719.short13:05
BrainstormNew from BMJ Open: Codesign of a digital health tool for suicide prevention: protocol for a scoping review: Introduction The role of digital health in providing psychological treatment and support for the prevention of suicide is well documented. Particular emphasis has been placed on digital health technologies during [... want %more?] → http://bmjopen.bmj.com/cgi/content/short/13/3/e07032913:15
BrainstormNew from Reddit (test): CoronaVirus_2019_nCoV: The Intersection of Pain and COVID-19 with Soo Kim, MD - Pain Matters Podcast Network | Podcast on Spotify → https://old.reddit.com/r/CoronaVirus_2019_nCoV/comments/11nnp6n/the_intersection_of_pain_and_covid19_with_soo_kim/13:24
BrainstormNew from BMJ: Covid-19: Latin America must reduce its reliance on medical imports: Countries across the Americas and the Caribbean must bolster their surveillance of covid-19 and continue to vaccinate against the disease if they are to leave the pandemic behind, senior officials at the Pan American Health Organization (PAHO) [... want %more?] → http://www.bmj.com/content/380/bmj.p576.short14:23
BrainstormNew from COVID on Twitter: (translated) Tom Wenseleers (@TWenseleers): If these were supposed to be the kind of clowns who should come and evaluate our Covid policy... Poor Flanders... Stick to that OECD report... twitter.com/pjvanerp/statu... → https://twitter.com/TWenseleers/status/163418874281761996814:53
BrainstormUpdates for Kosovo: +36 cases since 23 hours ago15:02
BrainstormNew from COVID on Twitter: (translated) Marc Veldhoen (@Marc_Veld): Cabinet immediately scraps the latest corona rulesOn Friday, the cabinet decided to follow the advice of the OMT and to treat the corona virus as an everyday infection.nu.nl/coronavirus/62… → https://twitter.com/Marc_Veld/status/163419437656900403315:13
BrainstormNew from r/Coronavirus: Coronavirus: Netherlands drops remaining Covid measures and advice 1,107 days after 1st positive test → https://old.reddit.com/r/Coronavirus/comments/11nr9by/netherlands_drops_remaining_covid_measures_and/16:02
BrainstormNew from COVID on Twitter: Marc Veldhoen (@Marc_Veld): Contrary to the idea that Covid was the result of either malicious or irresponsible lab tinkering, this virus was originally found in nature before escaping from a lab, if the reports are true. → https://twitter.com/Marc_Veld/status/163420961267192627316:12
BrainstormNew from COVID on Twitter: Eric Topol (@EricTopol): Unchanged US status for #SARSCoV2 genomics with XBB.1.5 accounting for 90% of new cases, no new variants showing growth advantagecovid.cdc.gov/covid-data-tra…I reviewed implications here:erictopol.substack.com/p/a-break-from… pic.twitter.com/PST3C7wr9l → https://twitter.com/EricTopol/status/163421694670614119016:41
BrainstormNew from COVID on Twitter: Eric Topol (@EricTopol): The pandemic at 3 yearsapnews.com/article/covid-… by @CarlaKJohnson @AP → https://twitter.com/EricTopol/status/163422132566873702517:01
LjLSometimes I'm really confused about Matrix and the bridge. I just told the other day that unfortunately, yes, you get ejected from the Matrix room as well when the bridge kicks you "for being idle", and I thought that was also true for rooms where allowUnconnectedUsers=true because... i thought that was such a room... but now it did it with so many people here, but none of them shows up as actually having quit on Matrix17:27
BrainstormNew from Reddit (test): CoronaVirus_2019_nCoV: Long Covid treatment can lead to debt after insurance denies claims: Millions in the U.S. are out of work because of severe long Covid symptoms, and many are struggling to pay their medical bills → https://old.reddit.com/r/CoronaVirus_2019_nCoV/comments/11ntnbr/long_covid_treatment_can_lead_to_debt_after/17:31
BrainstormNew from COVID on Twitter: Balazs Lab (@BalazsLab): If you're still struggling to understand the implications from the recent Lancet paper on natural immunity vs. vaccine-induced COVID-19 immunity, we recently contributed our perspective to this wonderful piece by @factcheckdotorg 's @kateyandell.factcheck.org/2023/03/sciche… → https://twitter.com/BalazsLab/status/163422992265816064217:40
BrainstormNew from ClinicalTrials.gov: (news): DAOIB for the Treatment of Brain Fog → https://clinicaltrials.gov/ct2/show/NCT0576453818:20
BrainstormNew from WebMD: FDA Approves Fast-Acting Nasal Spray for Migraines, Pfizer Says: Clinical trials showed the nasal spray provided migraine relief within 15-30 minutes of use, with the relief lasting up to 48 hours in many patients. → https://www.webmd.com/migraines-headaches/news/20230310/fda-approves-nasal-spray-for-migraines18:40
BrainstormNew from COVID on Twitter: Jamie Metzl (@JamieMetzl): I  believe a research-related #COVID19 origin is most likely, but none of us should blindly defend our preferred hypothesis to the death. The whole point is to keep challenging each other and ourselves until get to the right answer. → https://twitter.com/JamieMetzl/status/163424916734516430019:00
Spec_whoa there19:20
Spec_> It works by blocking the peptide receptors that cause inflammation that often comes with migraine.19:22
LjLSpec_, i don't know why that is important19:39
BrainstormNew from r/COVID19: COVID19: Pharmacological disruption of mSWI/SNF complex activity restricts SARS-CoV-2 infection → https://old.reddit.com/r/COVID19/comments/11nx56q/pharmacological_disruption_of_mswisnf_complex/19:49
LjLSpec_, or to put it in other words, i'd like to know why you quoted that19:53
BrainstormNew from COVID on Twitter: Michael Lin, MD PhD   (@michaelzlin): "Since we observed all notable SARSCoV2 features ... in related coronaviruses in nature, we do not believe that any type of lab-based scenario is plausible."Why can't a natural coronavirus go to Wuhan via a lab, especially since thousands already [... want %more?] → https://twitter.com/michaelzlin/status/163426564591439052819:59
ublxthis take isn't exactly making it sounds like a panacea: https://practicalneurology.com/news/new-nasal-spray-treatment-for-migraine-approved20:10
ublx"... this phase 3 study, published in the March issue of The Lancet Neurology, showed that, 2 hours post-dose, a higher percentage of individuals treated with zavegepant 10 mg nasal spray reported more pain freedom and freedom from their most bothersome symptom than those administered a placebo."20:11
ublxthis appears to be the lancet article referenced: https://www.thelancet.com/journals/laneur/article/PIIS1474-4422(22)00517-8/fulltext20:13
BrainstormNew from r/COVID19: COVID19: Effectiveness of BNT162b2 vaccination in preventing COVID-19–associated death in Poland → https://old.reddit.com/r/COVID19/comments/11ny8mw/effectiveness_of_bnt162b2_vaccination_in/20:28
LjLublx, yes the lancet article is immediately referenced in the bot's article :P20:37
ublxoh lol20:37
ublxi too am curious to know why Spec_ finds this mechanism of action alarming20:39
LjL2 h after the treatment dose, more participants in the zavegepant group than in the placebo group had pain freedom (147 [24%] of 623 participants vs 96 [15%] of 646 participants20:39
LjLublx, when you deal with Spec_ you have to get used to hit-and-runs and maaaybe he'll answer in some eight hours :P20:39
LjLsadly the full paper isn't free to read20:40
LjLso it would be interesting to see how many had "pain relief", since "pain freedom", yeah, better than nothing, but not so great20:40
ublxhmm. i'd kinda thonk that 'freedom' would be a term of art denoting absence of pain, while relief might denote improvement along gradations of pain20:45
ublxnow that i think about it20:45
LjLyes20:47
LjLbut "freedom" was only attained in 24% of those people20:47
LjLwhich is better than placebo's 15%, but when i take something to make migraine go away, knowing that it has a 24% chance of actually going away is not great20:47
LjLso the next best thing to ask is: how many people had some *relief* from the migraine, even if it didn't entirely go away?20:48
BrainstormNew from COVID on Twitter: Michael Lin, MD PhD   (@michaelzlin): "Since we observed all notable SARSCoV2 features ... in nature, we do not believe that any type of lab-based scenario is plausible."The parsimonious possibility of an accidental leak of a natural the lab was never mentioned. → https://twitter.com/michaelzlin/status/163427769044972748920:48
LjLLin has become a staunch proponent of the lab leak hypothesis it seems20:48
LjLi agree though...20:49
ublxi read (ok, skimmed) Oliver Sacks' book on migraine twenty odd years ago, and when my eyes landed on the phrase "frequency and severity improve with age" i closed the book and decided that was the treatment plan for me20:54
ublxin hindsight, probably a mistake. took twenty years for severity to dwindle to mere headache severity20:57
LjLmy mom is 72 and still gets migraines with aura...20:59
LjLthough more often without.21:00
ublxmy residual headaches still seem to come from the same stable, but no longer any aura/nausia/prodrome/postdrome. just a normalish severity headache with vaguely menacing undertones. down from monthly to a couple of times a year maybe21:04
LjLthe perks of old age! sometimes.21:06
BrainstormNew from COVID on Twitter: Eric Topol (@EricTopol): Yet another pan-sarbecovirus (#SARSCoV2 variant-proof) vaccine candidate, this one with effective neutralization vs the BQ.1.1 and XBB variants in non-human primates pnas.org/doi/10.1073/pn… @PNASNews Bu none of these have progressed to clinical trials pic.twitter.com/YratTfR9fU → https://twitter.com/EricTopol/status/163429397358931968421:47
BrainstormNew from Contagion Live: The Most-Read Infectious Disease Stories This Week: Increases in human metapneumovirus, adverse events in long COVID patients, and new hepatitis B testing and screening guidelines were among this week's most-read stories. Rounding out our Top 5 are patient experiences [... want %more?] → https://www.onclive.com/view/the-most-read-infectious-disease-stories-this-week22:06
BrainstormNew from NPR Science: On 3/11/20, WHO declared a pandemic. These quotes and photos recall that historic time: Three years ago, the novel coronavirus swept the world. Here are 24 quotes and 13 photos that sum up the reaction in the [... want %more?] → https://www.npr.org/sections/goatsandsoda/2023/03/10/1162169741/on-3-11-20-who-declared-a-pandemic-these-quotes-and-photos-recall-that-historic-22:35
BrainstormUpdates for Montenegro: +80 cases, +666 tests since a day ago — Morocco: +36 cases, +2627 tests since 4 days ago23:08
LjLtest_, test__, flooded: your names do kinda seem to reflect your behavior. hopefully doesn't need to continue for too long23:34

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