libera/##covid-19/ Friday, 2023-02-17

BrainstormNew from Reddit (test): CoronaVirus_2019_nCoV: Can the “world’s first intranasal COVID vaccine” help spur booster uptake in India? | The intranasal vaccine is a recombinant adenoviral vectored vaccine, developed in partnership with Washington University, St Louis. → https://old.reddit.com/r/CoronaVirus_2019_nCoV/comments/1143vmn/can_the_worlds_first_intranasal_covid_vaccine/00:04
BrainstormUpdates for Guatemala: +488 cases, +1 deaths since 22 hours ago — Mali: +14 cases, +232 tests since 23 hours ago00:07
BrainstormNew from COVID on Twitter: Eric Topol (@EricTopol): Muscle biopsy in-depth assessment in people with #LongCovid w/ exercise symptoms compared with 2 control groups shows microvascular abnormalities with reduced capillaries, immune cell dysregulation, distinct gene expression signaturemedrxiv.org/content/10.110… [... want %more?] → https://twitter.com/EricTopol/status/162635895464014643200:23
BrainstormNew from The Lancet (Online): [Comment] COVID-19 infection, reinfection, and the transition to endemicity: Understanding the protection conferred by previous infection against repeat infection, illness, and severe disease is key to projecting the future epidemiology of COVID-19 and to [... want %more?] → https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(22)02634-4/fulltext00:33
BrainstormNew from COVID on Twitter: Eric Topol (@EricTopol): Link thelancet.com/journals/lance…Graph shows comparison vs vaccination for different outcomes over timeConclusion pulls a lot of data all togetherWork by @IHME_UW team pic.twitter.com/ucnoWJ0SB8 → https://twitter.com/EricTopol/status/162636758291070976100:52
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BrainstormLjL, It says: Our findings show that immunity from COVID-19 infection confers substantial protection against infection from pre-omicron variants. By comparison, protection against re-infection from the omicron BA.1 variant was substantially reduced and wanes rapidly over time. Protection against severe disease, although based on scarce data, was maintained at a relatively high level [... want %more?]00:59
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BrainstormLjL, [...] up to 1year after the initial infection for all variants. Our analysis suggests that the level of protection from past infection by variant and over time is at least equivalent if not greater than that provided by two-dose mRNA vaccines. → https://paste.ee/p/pbsQ201:00
BrainstormLjL, [...] guiding vaccine policy decisions. In The Lancet, The COVID-19 Forecasting Team1 report data from a systematic review and meta-analysis of 65 studies from 19 different countries estimating the reduction in COVID-19 risk among individuals with previous SARS-CoV-2 infection, compared with those without a previous infection. → https://paste.ee/p/VdST101:00
BrainstormUpdates for California, United States: +12625 cases since 4 days ago — Canada: +6040 cases, +88 deaths since 23 hours ago01:09
BrainstormNew from COVID on Twitter: Eric Topol (@EricTopol): Good summary for infection-acquired immunity.The unpredictability of a Covid infection with respect to inducing severe disease and chance of developing #LongCovid pic.twitter.com/20YnGjtgPW → https://twitter.com/EricTopol/status/162637813297357619201:40
BrainstormNew from Reddit (test): CoronaVirus_2019_nCoV: An Old TB Vaccine Might Help Stave Off Diabetes, Cancer Alzheimer's, and more: against COVID, they found that across five trials, there was a 40 percent reduction in overall mortality in those who received BCG, [... want %more?] → https://old.reddit.com/r/CoronaVirus_2019_nCoV/comments/1146ac9/an_old_tb_vaccine_might_help_stave_off_diabetes/02:00
BrainstormNew from r/COVID19: COVID19: Study shows strong natural immunity to Covid-19 after 10 months → https://old.reddit.com/r/COVID19/comments/1146k3c/study_shows_strong_natural_immunity_to_covid19/02:09
BrainstormUpdates for Australia: +9373 cases, +107 deaths since 6 days ago02:11
BrainstormNew from r/COVID19: COVID19: SARS-CoV-2 NSP5 Antagonizes the MHC II Antigen Presentation Pathway by Hijacking Histone Deacetylase 2 → https://old.reddit.com/r/COVID19/comments/114785j/sarscov2_nsp5_antagonizes_the_mhc_ii_antigen/02:48
BrainstormUpdates for Haiti: +67 cases since 15 days ago03:01
BrainstormNew from r/Coronavirus: Coronavirus: Covid-19 infection offers strong protection against reinfection for about 10 months, study finds | CNN → https://old.reddit.com/r/Coronavirus/comments/1147j0z/covid19_infection_offers_strong_protection/03:17
BrainstormUpdates for Pakistan: +37 cases since 23 hours ago04:03
BrainstormNew from r/COVID19: COVID19: Past SARS-CoV-2 infection protection against re-infection: a systematic review and meta-analysis → https://old.reddit.com/r/COVID19/comments/1149q6l/past_sarscov2_infection_protection_against/04:45
BrainstormUpdates for Germany: +16393 cases, +90 deaths since a day ago06:07
BrainstormUpdates for Ohio, United States: +8999 cases since 4 hours ago — Ontario, Canada: +5135 cases, +58 deaths since 2 days ago — Minnesota, United States: +4967 cases, +60 deaths since 7 days ago — Moscow, Russia: +3782 cases, +11 deaths since a day ago07:10
BrainstormNew from WebMD: Advocates Decry ‘Environmental Apartheid’ in Port Cities: Shipping industries boomed during the pandemic. Without the protection of a gutted Environmental Protection Agency, communities next door are paying the price. → https://www.webmd.com/lung/features/port-pollution-respiratory-disease08:36
BrainstormNew from r/Coronavirus: Daily Discussion Thread | February 17, 2023: Please refer to our Wiki for more information on COVID-19 and our sub. You can find answers to frequently asked questions in our FAQ , where there is valuable information such as our: → https://old.reddit.com/r/Coronavirus/comments/114e2ir/daily_discussion_thread_february_17_2023/09:04
BrainstormNew from r/COVID19: COVID19: Results from a systematic programme of evaluating COVID-19 reinfection cases in the early phase of the pandemic, Singapore → https://old.reddit.com/r/COVID19/comments/114ffzs/results_from_a_systematic_programme_of_evaluating/10:41
BrainstormNew from COVID on Twitter: (translated) Cis Rits (@cisrits): Clear story from @MarionKoopmansabout discontinuing follow-up research @WHOby origin #SARSCoV2.  volkskrant.nl/nieuws-background…hln.be/buitenland/qua… → https://twitter.com/cisrits/status/162652314074137395311:20
BrainstormNew from r/COVID19: COVID19: Disease severity in hospitalized COVID-19 patients: comparing routine surveillance with cohort data from the LEOSS study in 2020 in Germany → https://old.reddit.com/r/COVID19/comments/114h41f/disease_severity_in_hospitalized_covid19_patients/11:49
BrainstormNew from BMJ: Virtual wards: urgent care policy must follow the evidence: NHS urgent and emergency care is under unbearable strain, which is increasingly causing harm to patients.1 Overcrowding in emergency departments and stasis in acute medical units—driven by workforce and capacity constraints—prevent timely and high [... want %more?] → http://www.bmj.com/content/380/bmj.p343.short12:37
BrainstormNew from COVID on Twitter: (translated) Marc Veldhoen (@Marc_Veld): @VrijheidVrede think something now for a 3rd time ebwering, without explanation, #explaining is. Can't read, can't make an argument and doesn't understand that the C19 is a 3-dose vaccine. But it does have a big mouth. pic.twitter.com/jJNJKF0QfH → https://twitter.com/Marc_Veld/status/162655440730209485013:16
BrainstormUpdates for Russia: +15359 cases, +38 deaths since 23 hours ago — Nepal: +5 cases since 22 hours ago14:01
BrainstormNew from StatNews: STAT+: Pfizer scraps half of participants in Lyme disease drug trial due to quality issues: Pfizer and partner Valneva's trial for a Lyme disease vaccine candidate hit a snag due to quality issues with a third-party trial operator. → https://www.statnews.com/2023/02/17/pfizer-scraps-half-of-participants-in-lyme-disease-drug-trial-due-to-quality-issues/14:23
BrainstormNew from EMA: Human medicine assessment reports: (news): Human medicines European public assessment report (EPAR): Jcovden (previously COVID-19 Vaccine Janssen), COVID-19 vaccine (Ad26.COV2-S [recombinant]), COVID-19 virus infection, Date of authorisation: 11/03/2021, Revision: [... want %more?] → https://www.ema.europa.eu/en/medicines/human/EPAR/jcovden-previously-covid-19-vaccine-janssen14:33
BrainstormNew from COVID on Twitter: Marc Veldhoen (@Marc_Veld): Ischemic stroke after COVID-19 bivalent vaccine administration in patients aged 65 years and older: analysis of nation-wide patient electronic health records in the United States Is there any concern regarding vaccines in elderly and strokes?medrxiv.org/content/10.110… → https://twitter.com/Marc_Veld/status/162658510968730829515:23
BrainstormNew from EMA: What's new: SMOPs: Summary of opinion: Coxevac,inactivated Coxiella burnetii vaccine,  15/02/2023,  Positive → https://www.ema.europa.eu/en/medicines/veterinary/summaries-opinion/coxevac-015:33
BrainstormNew from COVID on Twitter: Marc Veldhoen (@Marc_Veld): This is infection protection only! So, that will wane in time; but protection against viral dissemination, and hence disease and other effects will be and remain high! Differences between Moderna and BioNtech are difficult to judge due to different timings. [... want %more?] → https://twitter.com/Marc_Veld/status/162659245904745676815:53
BrainstormNew from COVID on Twitter: Eric Topol (@EricTopol): From the Lancet paper, the difference in health care policy for prior Covid in the US and other countries pic.twitter.com/VUJpaTSIrB → https://twitter.com/EricTopol/status/162659518503888076816:03
BrainstormUpdates for Azerbaijan: +28 cases, +1 deaths since 20 hours ago16:05
BrainstormNew from EMA: Human medicine assessment reports: (news): Human medicines European public assessment report (EPAR): COVID-19 Vaccine (inactivated, adjuvanted) Valneva, COVID-19 vaccine (inactivated, adjuvanted, adsorbed), COVID-19 virus infection, Date of authorisation: [... want %more?] → https://www.ema.europa.eu/en/medicines/human/EPAR/covid-19-vaccine-inactivated-adjuvanted-valneva16:13
BrainstormNew from r/Science: science: Immunity acquired from a Covid infection was found to be “at least as high, if not higher” than that provided by two doses of an mRNA vaccine → https://old.reddit.com/r/science/comments/114p6zm/immunity_acquired_from_a_covid_infection_was/17:02
BrainstormUpdates for Italy: +28347 cases, +299 deaths since 6 days ago — Spain: +7038 cases, +210 deaths since 6 days ago17:07
BrainstormNew from ClinicalTrials.gov: (news): To Evaluate the Safety, Efficacy,and Pharmacokinetics of Orally Administered Prolectin-M → https://clinicaltrials.gov/ct2/show/NCT0573378017:12
BrainstormNew from ClinicalTrials.gov: (news): Post COVID-19 REspiratory Mechanisms and the Efficacy of a Breathing Exercise Intervention for DYsregulated Breathing → https://clinicaltrials.gov/ct2/show/NCT0573257117:22
BrainstormNew from ClinicalTrials.gov: (news): MGC Health COVID-19 & Flu A+B Home Multi Test Usability Study → https://clinicaltrials.gov/ct2/show/NCT0573261017:31
BrainstormNew from ClinicalTrials.gov: Acute Coronary Syndrome in Patients With COVID-19: Condition :    to Find a Clinical or Laboratory Parameter, That Would Help in Distinguishing Between COVID-19 Patients With MI and IRA and Those, Who Have no IRA → https://clinicaltrials.gov/ct2/show/NCT0573259717:41
BrainstormUpdates for Netherlands: +1806 cases since 3 days ago — Chile: +1800 cases, +13 deaths since a day ago — Canada: +951 cases since 21 hours ago18:10
BrainstormNew from NPR Science: The Marburg outbreak in Equatorial Guinea is a concern — and a chance for progress: Marburg virus is hard to detect early on--and goes on to kill about half its victims. Researchers hope to work quickly [... want %more?] → https://www.npr.org/sections/goatsandsoda/2023/02/17/1157810407/the-marburg-outbreak-in-equatorial-guinea-is-a-concern-and-a-chance-for-progress18:31
BrainstormNew from COVID on Twitter: Marc Veldhoen (@Marc_Veld): While the results of this study support the neuroinvasive potential of SARS-CoV-2 and characterize the role of brainstem inflammation in COVID-19, its potential implications for neurodegeneration, especially in Parkinson’s disease, require further investigations! → https://twitter.com/Marc_Veld/status/162663539063010103318:41
BrainstormNew from r/Science: science: Hospital Outcomes of SARS-CoV-2 Omicron Variant vs Influenza in Switzerland: Omicron hospital illness 54% deadlier than flu hospital cases, study finds → https://old.reddit.com/r/science/comments/114tq10/hospital_outcomes_of_sarscov2_omicron_variant_vs/19:58
BrainstormNew from Contagion Live: How Protective Is a Past COVID-19 Infection Against Reinfection?: How likely is COVID-19 reinfection? A new study estimates the protection from past COVID-19 infection by variant and time since infection. → https://www.onclive.com/view/how-protective-is-a-past-covid-19-infection-against-reinfection-20:08
BrainstormNew from r/COVID19: COVID19: Benefits of near-universal vaccination and treatment access to manage COVID-19 burden in the United States → https://old.reddit.com/r/COVID19/comments/114vkfg/benefits_of_nearuniversal_vaccination_and/20:49
BrainstormNew from r/Coronavirus: Coronavirus: Idaho lawmakers introduce legislation to criminalize those who administer COVID vaccines → https://old.reddit.com/r/Coronavirus/comments/114vxtp/idaho_lawmakers_introduce_legislation_to/21:38
BrainstormNew from COVID on Twitter: Eric Topol (@EricTopol): When we think of the immune system, antibodies and B & T cells come to mind. But the extracellular matrix is key, and beautifully reviewed here @ScienceMagazinescience.org/doi/10.1126/sc… by @DrTESutherland  @tripledougdyer @ProfJudiAllen pic.twitter.com/xcsKJqN7Cz → https://twitter.com/EricTopol/status/162669330807563878522:27
BrainstormUpdates for Canada: +529 cases since 21 hours ago23:09

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