libera/##covid-19/ Saturday, 2023-01-07

BrainstormNew from COVID on Twitter: Gunhild Alvik Nyborg (@GANyborg): "If we assume R = 10 without testing (or significant other measures), we might expect daily testing to reduce the number of new cases by greater than a factor of 9 each week (see appendix); mass testing would not only reduce R but also the serial and [... want %more?] → https://twitter.com/GANyborg/status/161149737298650726400:10
BrainstormUpdates for Montenegro: +75 cases since a day ago — Albania: +37 cases since a day ago01:07
BrainstormNew from COVID on Twitter: Marc Veldhoen (@Marc_Veld): against Omicron BA.5 infection acquired by vaccination + Omicron BA.1/BA.2 infection) is stable over 8 months. Great in line with other HCoVs, suggesting an more seasonal pattern ahead. twitter.com/lgraca/status/… → https://twitter.com/Marc_Veld/status/161152271787373363601:48
BrainstormUpdates for Canada: +3332 cases, +67 deaths since 6 hours ago02:09
de-facto%print https://twitter.com/DrEricDing/status/161150942307119104003:41
Brainstormde-facto, It says: Eric Feigl-Ding on Twitter: "Hospitalization ⬆️2x surging—but cases flat?? What’s going is testing has crashed and #COVID19 case numbers unreliable. ➡️Hospital and wastewater in MA don’t lie. Uncoupling—but in the WRONG WAY… opposite of last year. 📌Driven by #XBB15 strain. Don’t ignore the #Kraken. #MaskUp https://t.co/mNw9mSMjjG" / Twitter03:41
BrainstormNew from r/Science: science: Not wearing a mask and being unvaccinated was associated with Covid-19. There was a 49% higher chance of COVID-19 compared to people who are vaccinated and mask consistently. → https://old.reddit.com/r/science/comments/105boy2/not_wearing_a_mask_and_being_unvaccinated_was/03:54
BrainstormUpdates for Germany: +13169 cases, +170 deaths since 23 hours ago05:04
LjLde-facto, you said we should send vaccines to China? maybe you should get them to agree first... <Brainstorm> New from r/WorldNews: worldnews: China has rebuffed repeated US offers to share advanced vaccines as Beijing battles a fast-spreading wave of Covid-19, a rejection that’s led to growing frustration among American officials concerned about a resurgence of the pandemic. → https://old.reddit.com/r/worldnews/comments/105e19y/china_has_rebuffed_repeated_us_o05:04
LjLffers_to_share/05:04
de-factoBiontech too afaik05:05
de-factoScholz offered it when he traveled to CHina05:05
de-factoall he could reach was that China allows usage of BioNTech in China for foreigners05:06
ublxpossibly relevant angle: https://www.nakedcapitalism.com/2023/01/germany-the-birthplace-of-the-pfizer-biontech-covid-19-vaccine-now-wants-to-cancel-its-vaccine-deal.html05:06
de-factoyeah at the start we did not have enough doses fast enough, now we have more than enough doses but people dont take them anymore05:07
de-factobtw i read that some said XBB.1.5 may also have reached CHina, but since we dont really have reliable data we only would know if travelers come back carrying it05:09
BrainstormNew from r/Coronavirus: Coronavirus: Mazraoui latest with COVID-related heart issue → https://old.reddit.com/r/Coronavirus/comments/105cf2y/mazraoui_latest_with_covidrelated_heart_issue/05:42
BrainstormNew from This Week In Virology: TWiV 972: Clinical update with Dr. Daniel Griffin: In his weekly clinical update Dr. Griffin discusses the infectiousness of SARS-CoV-2 breakthrough infections and reinfections during the Omicron wave, virological characteristics of the SARS-CoV-2 XBB variant derived from recombination of two Omicron [... want %more?] → https://www.microbe.tv/twiv/twiv-972/06:11
BrainstormUpdates for Florida, United States: +31968 cases, +161 deaths since a day ago — Tokyo, Japan: +20720 cases, +29 deaths since a day ago — Osaka, Japan: +15957 cases, +29 deaths since a day ago — Aichi, Japan: +15928 cases, +16 deaths since a day ago07:08
BrainstormNew from r/Coronavirus: Daily Discussion Thread | January 07, 2023: Please refer to our Wiki for more information on COVID-19 and our sub. You can find answers to frequently asked questions in our FAQ , where there is valuable information such as our: → https://old.reddit.com/r/Coronavirus/comments/105jk4b/daily_discussion_thread_january_07_2023/09:04
BrainstormNew from COVID on Twitter: Marc Veldhoen (@Marc_Veld): -The incidence and severity of MIS-C declined during the Omicron wave of the COVIUD-19 pandemic compared with earlier waves, although the precise reason for this decline remains to be determined. → https://twitter.com/Marc_Veld/status/161164534757444812809:54
BrainstormUpdates for Japan: +216512 cases, +455 deaths since 23 hours ago — Aguascalientes, Mexico: +307 cases since 2 days ago — Coahuila, Mexico: +260 cases since 2 days ago — Nayarit, Mexico: +173 cases since 2 days ago10:09
BrainstormNew from r/COVID19: COVID19: Safety and Immunogenicity of a Booster Dose of Novavax COVID-19 Vaccine, Adjuvanted (NVX-CoV2373) in Adults from the PREVENT-19 Trial in the United States → https://old.reddit.com/r/COVID19/comments/105l1r0/safety_and_immunogenicity_of_a_booster_dose_of/10:33
BrainstormNew from r/COVID19: COVID19: In Silico Analysis Reveals the Inhibitory Potential of Madecassic Acid against Entry Factors of SARS-CoV-2 → https://old.reddit.com/r/COVID19/comments/105lpj0/in_silico_analysis_reveals_the_inhibitory/11:20
BrainstormNew from Reddit (test): CoronaVirus_2019_nCoV: Experts: Underuse of COVID-19 drug Paxlovid shortchanging patients - that is likely costing patients unnecessary hospitalizations and even deaths → https://old.reddit.com/r/CoronaVirus_2019_nCoV/comments/105lta1/experts_underuse_of_covid19_drug_paxlovid/11:30
BrainstormNew from r/COVID19: COVID19: Neonates born to mothers with SARS-CoV-2 infection in pregnancy: a follow-up and serological study → https://old.reddit.com/r/COVID19/comments/105mfqs/neonates_born_to_mothers_with_sarscov2_infection/12:08
BrainstormNew from COVID on Twitter: Tulio de Oliveira (@Tuliodna): In spite of XBB.1.5 from U.S.A. & explosive wave in China. I do NOT expect a big wave of infections with hospitalization in SA due to high pop. immunity & previous waves of Omicron lineages. XBB.1.5 is still Omicron & anyone worried should get a booster. [... want %more?] → https://twitter.com/Tuliodna/status/161168107572967833612:18
BrainstormNew from COVID on Twitter: andrew merrifield (@andrewmerrifie7): @Tuliodna where does one get a booster? As far as I have heard - the public sector no longer does vaccinations and the private sector companies that did stopped because the state did not pay them for them ones they provided earlier... → https://twitter.com/andrewmerrifie7/status/161168952715582259412:56
BrainstormNew from COVID on Twitter: Tulio de Oliveira (@Tuliodna): The variants found in China are the Omicron BA.5 sub-lineages (which caused the last wave of infection in SA), the XBB.1.5 emerged in the East Coast of the U.S.A. More info on XBB.1.5, which is still Omicron, at: theguardian.com/world/2023/jan… twitter.com/KKhoabane/stat… → https://twitter.com/Tuliodna/status/161169447732378419513:05
BrainstormNew from Politico: Beijing clamps down on social media critics of COVID policies: Chinese social media platform Sina Weibo issues temporary or permanent bans on 1,120 accounts. → https://www.politico.eu/article/china-zero-covid-policy-coronavirus-social-media-critics-sina-weibo/13:44
BrainstormNew from Retraction Watch: Weekend reads: China cracks down; unearned authorship rife; new jargon for a new year: Would you consider a donation to support Weekend Reads, and our daily work? The week at Retraction Watch featured: Our list of retracted [... want %more?] → https://retractionwatch.com/2023/01/07/weekend-reads-china-cracks-down-unearned-authorship-rife-new-jargon-for-a-new-year/14:13
BrainstormNew from COVID on Twitter: Marc Veldhoen (@Marc_Veld): Correction!-SARS-CoV-2 spike protein does NOT act as a superantigen; the skewing of Vβ21.3 expression on T cells in children with MIS-C is most likely attributable to a non-SARS-CoV-2 related antigen. → https://twitter.com/Marc_Veld/status/161171735642161561614:42
BrainstormNew from r/COVID19: COVID19: Catching CAPA: The Healthcare Impact of COVID-19-Associated Pulmonary Aspergillosis in an Academic Medical Center → https://old.reddit.com/r/COVID19/comments/105pplq/catching_capa_the_healthcare_impact_of/15:11
BrainstormNew from COVID on Twitter: Tom Wenseleers (@TWenseleers): So for those that are rather safe than sorry : just get your bivalent booster, and that's it... It is also expected that the growth rate advantage of XBB.1.5 will decline over time as more people get infected & the pool of susceptibles shrinks... → https://twitter.com/TWenseleers/status/161173125295187968015:31
BrainstormUpdates for Azerbaijan: +120 cases, +4 deaths since a day ago — Iran: +107 cases, +2 deaths since a day ago16:10
BrainstormNew from COVID on Twitter: Marc Veldhoen (@Marc_Veld): Nice explanation of why the infection interval and time of neutralising antibody interval will determine the frequency of SARS-CoV-2 waves and their amplitude. It looks that SARS-CoV-2 is going to be on a similar path as the HCoVs we know OC43, HKU.1, 229E and [... want %more?] → https://twitter.com/Marc_Veld/status/161175683391969689717:18
BrainstormUpdates for Cuba: +28 cases since a day ago18:02
BrainstormNew from Reddit (test): CoronavirusUK: Summary of Product Characteristics for VidPrevtyn Beta dispersion for injection → https://old.reddit.com/r/CoronavirusUK/comments/105uf89/summary_of_product_characteristics_for_vidprevtyn/18:45
BrainstormNew from COVID on Twitter: (translated) Marc Veldhoen (@Marc_Veld): Conclusion:No data, pure speculation from not understanding literature, anti-vaccination bias, exaggerating things. This is very bad, and unfortunately dangerous, disinformation. → https://twitter.com/Marc_Veld/status/161178859499314381219:25
BrainstormNew from Contagion Live: Certain Genes May Naturally Protect Against Severe COVID-19: A Brazilian study of people 90 years and older who easily recovered from COVID-19 identified specific genetic components that may have provided protection. → https://www.contagionlive.com/view/certain-genes-may-naturally-protect-against-severe-covid-1919:44
BrainstormNew from COVID on Twitter: Eric Topol (@EricTopol): But in North Carolina, with much lower % XBB.1.5, a similar spike in hospital admissions among seniors, which supports other factors besides this variant as a principal driver pic.twitter.com/1nk28wAwHT → https://twitter.com/EricTopol/status/161179746664251801619:54
BrainstormUpdates for Malaysia: +571 cases, +4 deaths since a day ago20:00
BrainstormNew from r/Science: science: A randomized double-blind controlled trial found post-exposure prophylaxis with hydroxychloroquine (HCQ) was not advantageous for the prevention of COVID-19 in asymptomatic individuals with high risk for SARS-CoV-2 infection. The incidence of [... want %more?] → https://old.reddit.com/r/science/comments/105wwo9/a_randomized_doubleblind_controlled_trial_found/20:33
BrainstormNew from r/Coronavirus: Coronavirus: Health Experts Warily Eye XBB.1.5, the Latest Omicron Subvariant → https://old.reddit.com/r/Coronavirus/comments/105x0l3/health_experts_warily_eye_xbb15_the_latest/20:52
BrainstormNew from r/COVID19: COVID19: Stability of hybrid versus vaccine immunity against BA.5 infection over 8 months → https://old.reddit.com/r/COVID19/comments/105ytw2/stability_of_hybrid_versus_vaccine_immunity/21:41
LjLde-facto, https://www.contagionlive.com/view/certain-genes-may-naturally-protect-against-severe-covid-19 this suggests that at least in older people, not having so much inflammatory activity does help. i wonder if it relates to the IgG4 antibodies stuff in any way.22:03
de-factohmm but werent those IgG4 Abs seen in almost everyone after 3rd dose or infection?22:07
de-facto(not sure if i remember correctly)22:08
LjLde-facto, yes what i'm saying is maybe it's a good thing, because they are less pro-inflammatory than IgG1 and others22:08
LjLyou already said that might be the case, just the above observations may strengthen that hypothesis22:09
de-factoyeah my thoughts too, but it also could be indicating ongoing long term inflammatory issues22:09
de-factoso it can be seen from both perspectives, hence my uncertainty if its good or bad22:09
BrainstormNew from ##covid-19 Zotero group: Health Experts Warily Eye XBB.1.5, the Latest Omicron Subvariant: Type Newspaper Article Author Carl Zimmer URL https://www.nytimes.com/2023/01/07/science/covid-omicron-variants-xbb.html Publication The New York Times ISSN 0362-4331 Date 2023-01-07 Section Science Accessed 2023-01-07 [... want %more?] → https://www.zotero.org/groups/covid_links/items/J5I3FIZ422:10
de-factoas far as I understand it its a way of the body to deal with an antigen that causes too much inflammatory issues, hence since inflammatory issues are a major cause of problematic COVID progressions (as can be seen by treatment with immuno-suppressants) it may be helpful if the immune system already got the capability to deal with such situations22:14
de-factobut it also may mean that there was an inflammatory issue causative for learning that capability22:15
de-factonot sure if those assumptions hold, immunology is very complex22:15
BrainstormUpdates for Canada: +752 cases, +17 deaths since 20 hours ago23:07

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