libera/##covid-19/ Thursday, 2022-12-22

BrainstormNew from COVID on Twitter: Eric Topol (@EricTopol): Full text. One of multiple lab studies now to show the bivalent booster helps increase the immune (neutralizing antibody) response vs BQ.1.1 and XBB pic.twitter.com/dejyM7rNrb → https://twitter.com/EricTopol/status/160569949412895129600:02
BrainstormNew from r/COVID19: COVID19: SARS-CoV-2 variant-specific differences in inhibiting the effects of the PKR-activated integrated stress response → https://old.reddit.com/r/COVID19/comments/zs58j3/sarscov2_variantspecific_differences_in/00:41
BrainstormNew from COVID on Twitter: (translated) Marc Veldhoen (@Marc_Veld): BA.5 bivalent vaccines also work well; better than the monovalent as a booster. However: T cell immunity has been achieved with 3 vaccines in the non-vulnerable group: a booster gives better protection against infection of yourself and your loved [... want %more?] → https://twitter.com/Marc_Veld/status/160571339966017126401:00
BrainstormUpdates for Tennessee, United States: +10487 cases, +80 deaths since 6 days ago — Bolivia: +2797 cases, +3 deaths since a day ago — Norway: +329 cases since 23 hours ago — Canada: +2355 cases, +43 deaths since 5 hours ago02:10
BrainstormUpdates for Guyana: +206 cases, +1 deaths since 8 days ago — North Macedonia: +205 cases, +9 deaths since 7 days ago03:00
BrainstormNew from Nature Vaccines: Alejandro M. Gomez et al.: A novel intradermal tattoo-based injection device enhances the immunogenicity of plasmid DNA vaccines → https://www.nature.com/articles/s41541-022-00581-y05:00
BrainstormUpdates for Germany: +47988 cases, +178 deaths since a day ago — Laos: +60 cases since 23 hours ago06:06
BrainstormUpdates for Texas, United States: +26628 cases, +105 deaths since 23 hours ago — Louisiana, United States: +25438 cases, +21 deaths since 6 days ago — Tokyo, Japan: +21186 cases, +20 deaths since 23 hours ago — North Carolina, United States: +16676 cases, +49 deaths since 6 days ago07:02
BrainstormNew from Reddit (test): CoronaVirus_2019_nCoV: Woman has tested positive for COVID 12 times, will miss third Christmas with family → https://old.reddit.com/r/CoronaVirus_2019_nCoV/comments/zsd1r9/woman_has_tested_positive_for_covid_12_times_will/08:09
BrainstormNew from r/Coronavirus: Daily Discussion Thread | December 22, 2022: Please refer to our Wiki for more information on COVID-19 and our sub. You can find answers to frequently asked questions in our FAQ , where there is valuable information such as our: → https://old.reddit.com/r/Coronavirus/comments/zsgcym/daily_discussion_thread_december_22_2022/09:06
BrainstormUpdates for Taiwan: +19875 cases, +41 deaths, +26206 tests since 23 hours ago09:07
BrainstormNew from BMJ Open: Correlation between the ratio of physician consultation fees to hourly minimum wage and consultation length: a cross-sectional study of nine countries: Objectives Current healthcare reimbursement system is criticised for not adequately compensating physicians’ cognitive services. This study was [... want %more?] → http://bmjopen.bmj.com/cgi/content/short/12/12/e06436910:41
BrainstormNew from StatNews: Opinion: Lessons learned from the deadly combination of sepsis and Covid-19: We live in a world of microbes. They are not going away. Covid-19 and Covid-related sepsis have a lot to teach us, but only if we listen and learn. → https://www.statnews.com/2022/12/22/lessons-learned-deadly-combination-sepsis-covid-19/10:51
BrainstormUpdates for Russia: +7451 cases, +54 deaths since 23 hours ago10:59
BrainstormNew from r/COVID19: COVID19: Effectiveness of mRNA-1273, BNT162b2, and BBIBP-CorV vaccines against infection and mortality in children in Argentina, during predominance of delta and omicron covid-19 variants: test negative, case-control study → https://old.reddit.com/r/COVID19/comments/zsiamv/effectiveness_of_mrna1273_bnt162b2_and_bbibpcorv/11:01
BrainstormNew from r/COVID19: COVID19: FDA Approves Genentech’s Actemra for the Treatment of COVID-19 in Hospitalized Adults → https://old.reddit.com/r/COVID19/comments/zsiibx/fda_approves_genentechs_actemra_for_the_treatment/11:10
BrainstormNew from Virological.org: Latest posts: The comparative recency of the proximal ancestors of SARS-CoV-1 and SARS-CoV-2: Hello, I’m looking at figure 3, and I was wondering if you could clarify what the dates are. The date of sampling? The date of [... want %more?] → https://virological.org/t/the-comparative-recency-of-the-proximal-ancestors-of-sars-cov-1-and-sars-cov-2/906#post_211:39
BrainstormUpdates for Slovenia: +2237 cases since 23 hours ago12:01
BrainstormNew from BioNTech: BioNTech and Fosun Pharma Provide COVID-19 Vaccine Doses For Vaccination of German Expatriates in China: Approximately 11,500 of the companies’ mRNA-based COVID-19 vaccine doses arrived on the Chinese Mainland to enable vaccination [... want %more?] → https://investors.biontech.de/news-releases/news-release-details/biontech-and-fosun-pharma-provide-covid-19-vaccine-doses12:08
BrainstormNew from ECDC: Data on testing for COVID-19 by week and country: Data in multiple file formats with information about testing volume for COVID-19, sorted by week and country, and updated on a weekly basis. → https://www.ecdc.europa.eu/en/publications-data/covid-19-testing12:18
BrainstormUpdates for Israel: +2160 cases, +6 deaths since 15 hours ago13:04
BrainstormNew from ProPublica: A Water War Is Brewing Over the Dwindling Colorado River: by Abrahm Lustgarten ProPublica is a nonprofit newsroom that investigates abuses of power. Sign up to receive our biggest stories as soon as they’re published. On a crisp day this fall I drove southeast from [... want %more?] → https://www.propublica.org/article/colorado-river-water-uncompahgre-california-arizona13:43
BrainstormNew from r/COVID19: COVID19: Angiotensin receptor blockers for the treatment of covid-19: pragmatic, adaptive, multicentre, phase 3, randomised controlled trial → https://old.reddit.com/r/COVID19/comments/zsl9wf/angiotensin_receptor_blockers_for_the_treatment/14:00
BrainstormUpdates for Hong Kong: +19705 cases since 23 hours ago15:02
BrainstormNew from Virological.org: Latest posts: Preliminary Results from two novel “ARTIC-style” amplicon based sequencing approaches for RSV A and RSV B:  Daniel M Maloney1,2*; Goncalo Fernandes1*; Rebecca Dewar1; Aine O’Toole2; Chenge [... want %more?] → https://virological.org/t/preliminary-results-from-two-novel-artic-style-amplicon-based-sequencing-approaches-for-rsv-a-and-rsv-b/918#post_115:28
BrainstormUpdates for Croatia: +544 cases, +9 deaths, +2824 tests since a day ago16:04
BrainstormNew from EMA: Human medicine assessment reports: (news): Human medicines European public assessment report (EPAR): Paxlovid, nirmatrelvir,ritonavir, COVID-19 virus infection, Date of authorisation: 28/01/2022, Revision: 7, Status: Authorised → https://www.ema.europa.eu/en/medicines/human/EPAR/paxlovid16:16
BrainstormNew from EMA: Human medicine assessment reports: (news): Human medicines European public assessment report (EPAR): Imvanex, smallpox and monkeypox vaccine (Live Modified Vaccinia Virus Ankara), Smallpox Vaccine;Monkeypox virus, Date of authorisation: 31/07/2013, Revision: 23, Status: Authorised → https://www.ema.europa.eu/en/medicines/human/EPAR/imvanex16:25
BrainstormNew from r/COVID19: COVID19: Impact of SARS-CoV-2 exposure history on the T cell and IgG response → https://old.reddit.com/r/COVID19/comments/zspbr8/impact_of_sarscov2_exposure_history_on_the_t_cell/16:55
BrainstormNew from EMA: Human medicine assessment reports: (news): Human medicines European public assessment report (EPAR): Comirnaty, tozinameran,riltozinameran and tozinameran,famtozinameran and tozinameran,COVID-19 mRNA Vaccine (nucleoside modified), COVID-19 virus infection, Date of authorisation: 21/12/2020, Revision: [... want %more?] → https://www.ema.europa.eu/en/medicines/human/EPAR/comirnaty17:05
BrainstormUpdates for Kosovo: +5 cases since 23 hours ago17:06
BrainstormNew from Reddit (test): CoronavirusUK: The Last Post - Thursday 22 December 22 - England Hospitalisation Weekly Update (8Th - 21St December) + Final Note By Me → https://old.reddit.com/r/CoronavirusUK/comments/zspn04/the_last_post_thursday_22_december_22_england/17:15
BrainstormUpdates for Chile: +4931 cases, +50 deaths, +25050 tests since 23 hours ago — Cuba: +25 cases since 23 hours ago18:09
BrainstormNew from Reddit (test): nCoV: Global COVID Cases For 22DEC22 → https://old.reddit.com/r/nCoV/comments/zsr8gu/global_covid_cases_for_22dec22/18:13
BrainstormNew from COVID on Twitter: (translated) Marc Veldhoen (@Marc_Veld): There is no immunodeficiency due to SARS-CoV-2. It was made up to scare people. Confuse acute infection phase and exceptions such as longer activation in LC. twitter.com/penguinone/sta… → https://twitter.com/Marc_Veld/status/160597777252592025618:32
BrainstormNew from COVID on Twitter: Michael Lin, MD PhD   (@michaelzlin): Yesterday UK's MHRA approved GSK/Sanofi's protein-based COVID-19 vaccine (EU approved last month)The novel aspect of this vaccine is it uses Beta rather than original SARSCoV2 spikeInterestingly, works better on all tested variants, including [... want %more?] → https://twitter.com/michaelzlin/status/160598438086574489819:01
BrainstormNew from COVID on Twitter: Michael Lin, MD PhD   (@michaelzlin): The nice results for GSK/Sanofi's vaccine (now called VidPrevtyn Beta, quite a mouthful) show that there are alternatives to Novavax's approach. That is, GSK/Sanofi appears to have gotten better results with their new adjuvant without any nanoparticle formulation. → https://twitter.com/michaelzlin/status/160599088757345075219:21
BrainstormNew from COVID on Twitter: Michael Lin, MD PhD   (@michaelzlin): Finally, the timeline for VidPrevtyn Beta is still lightning fast by historical standards, with a 1-year interval from planning of Beta boosters to approval. But Pfizer-Moderna take the prize with 3 mo from FDA order for BA.5 bivalent boosters to rollout. → https://twitter.com/michaelzlin/status/160599314540924928019:30
BrainstormNew from COVID on Twitter: Michael Lin, MD PhD   (@michaelzlin): Even 6-mo turnarounds would need the right people and well-practiced execution on testing and manufacturing, however. Those may not have been in place in GSK/Sanofi or Novavax this year, but maybe next? → https://twitter.com/michaelzlin/status/160599401569384448019:40
BrainstormNew from COVID on Twitter: Michael Lin, MD PhD   (@michaelzlin): Oh, should add: VidPrevtyn Beta showed similar adverse events (AEs) as Pfizer while making more Abs. Thus old-fashioned recombinant protein vax may have better efficacy per AE than RNA.So a future of COVID19 vax without RNA, going back to basics, is [... want %more?] → https://twitter.com/michaelzlin/status/160599818747851980819:50
BrainstormNew from StatNews: Health: U.S. life expectancy falls for second straight year as drug overdose and Covid deaths take toll → https://www.statnews.com/2022/12/22/us-life-expectancy-falls-covid-drug-overdose-deaths/19:59
BrainstormUpdates for Ecuador: +6535 cases since 9 days ago — Luxembourg: +400 cases, +2 deaths since 22 hours ago — Canada: +2579 cases, +50 deaths since 22 hours ago — United Kingdom: +101 deaths since 22 hours ago20:01
BrainstormNew from COVID on Twitter: Eric Topol (@EricTopol): Late after mRNA Covid vaccines, or with booster or breakthrough infections, there is a shift to IgG4 antibodies, not seen with adenovirus vector vaccines. The clinical significance is not knownscience.org/doi/10.1126/sc… @SciImmunology @UniFAU pic.twitter.com/YozSLVjVLd → https://twitter.com/EricTopol/status/160600566544859545620:19
BrainstormNew from Contagion Live: Determining Long Term Immunity May Aid in Understanding Vaccine Efficacy: Virax Biolabs has developed a T-cell testing platform to develop an immune risk profile against viral threats. → https://www.contagionlive.com/view/determining-long-term-immunity-may-aid-in-understanding-vaccine-efficacy20:39
BrainstormNew from COVID on Twitter: Eric Topol (@EricTopol): My conversation this week with Prof @linseymarr, a civil engineer and leading authority on air quality, viruses, and the impact of masks. She's a remarkable explainer and my go-to expert on this topicmedscape.com/viewarticle/98… #COVIDIsAirborne @Medscape → https://twitter.com/EricTopol/status/160601773091352166521:09
BrainstormUpdates for Montenegro: +35 cases since a day ago21:09
BrainstormUpdates for France: +49517 cases, +120 deaths since 23 hours ago22:05
BrainstormNew from COVID on Twitter: Eric Topol (@EricTopol): Highest Covid hospitalizations in New York since January and soaring in seniors, as the XBB variant with added mutations gains growth advantage twitter.com/JPWeiland/stat… pic.twitter.com/AE7Gh7fQ1P → https://twitter.com/EricTopol/status/160604246785744486422:46
BrainstormNew from r/COVID19: COVID19: The OM-85 bacterial lysate inhibits SARS-CoV-2 infection of epithelial cells by downregulating SARS-CoV-2 receptor expression → https://old.reddit.com/r/COVID19/comments/zsyaxa/the_om85_bacterial_lysate_inhibits_sarscov2/23:15

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