libera/##covid-19/ Thursday, 2022-11-17

BrainstormUpdates for India: +398 cases since 17 hours ago00:09
BrainstormNew from BioNTech: Pfizer and BioNTech Advance Next-Generation COVID-19 Vaccine Strategy with Study Start of Candidate Aimed at  Enhancing Breadth of T cell Responses and Duration of Protection: NEW YORK and MAINZ, GERMANY, NOVEMBER 16, 2022 — [... want %more?] → https://investors.biontech.de/news-releases/news-release-details/pfizer-and-biontech-advance-next-generation-covid-19-vaccine00:39
BrainstormUpdates for Austria: +5041 cases, +11 deaths, +229552 tests since a day ago — Bolivia: +59 cases since 23 hours ago02:07
BrainstormUpdates for United Kingdom: +2 deaths since 4 days ago03:59
BrainstormUpdates for Bolivia: +66 cases since 2 hours ago — Pakistan: +57 cases, +1 deaths since a day ago05:02
BrainstormNew from r/Coronavirus: Coronavirus: Who Is Dying from COVID Now, and Why → https://old.reddit.com/r/Coronavirus/comments/yxf1m8/who_is_dying_from_covid_now_and_why/05:33
BrainstormUpdates for Germany: +33306 cases, +162 deaths since 23 hours ago — Laos: +34 cases since a day ago06:04
BrainstormUpdates for Rio de Janeiro, Brazil: +10199 cases, +16 deaths since 4 days ago — Indiana, United States: +5478 cases, +66 deaths since 6 days ago — Oregon, United States: +3355 cases, +44 deaths since 5 days ago — Paraiba, Brazil: +2113 cases, +5 deaths since 4 days ago07:00
BrainstormNew from Reddit (test): CoronaVirus_2019_nCoV: What is BN.1? Meet the newest Omicron spawn being tracked by the CDC → https://old.reddit.com/r/CoronaVirus_2019_nCoV/comments/yxigm6/what_is_bn1_meet_the_newest_omicron_spawn_being/07:17
BrainstormNew from EMA: Human medicine assessment reports: (news): Human medicines European public assessment report (EPAR): Vaxzevria (previously COVID-19 Vaccine AstraZeneca), COVID-19 Vaccine (ChAdOx1-S [recombinant]), COVID-19 virus infection, Date of authorisation: 29/01/2021, Revision: 25, Status: Authorised → https://www.ema.europa.eu/en/medicines/human/EPAR/vaxzevria08:51
BrainstormNew from r/Coronavirus: Daily Discussion Thread | November 17, 2022: Please refer to our Wiki for more information on COVID-19 and our sub. You can find answers to frequently asked questions in our FAQ , where there is valuable information such as our: → https://old.reddit.com/r/Coronavirus/comments/yxkbwg/daily_discussion_thread_november_17_2022/09:10
BrainstormNew from StatNews: Opinion: We know what it’s like to live in fear of polio. We also know how to stop it: Challenges like Covid-19 and natural disasters have disrupted polio-fighting activities in many countries, creating the condition for the virus to thrive and threaten people [... want %more?] → https://www.statnews.com/2022/11/17/eradicating-polio-lessons-learned-countries-fighting-it/10:55
BrainstormUpdates for Russia: +5680 cases, +61 deaths since 23 hours ago11:03
BrainstormNew from ProPublica: Public Schools Are NYC’s Main Youth Mental Health System. Where Kids Land Often Depends on What Their Parents Can Pay.: by Abigail Kramer ,  THE CITY, illustrations by Holly Stapleton , special to ProPublica This article was produced for ProPublica’s Local Reporting [... want %more?] → https://www.propublica.org/article/nyc-schools-kids-mental-health-special-education11:14
BrainstormNew from Reddit (test): nCoV: Global COVID Cases For 17NOV22 → https://old.reddit.com/r/nCoV/comments/yxnac6/global_covid_cases_for_17nov22/12:01
BrainstormNew from ECDC: Data on COVID-19 vaccination in the EU/EEA: Data in various file formats with information on COVID-19 vaccine doses administered, manufacturers, and target groups in the EU/EEA. → https://www.ecdc.europa.eu/en/publications-data/data-covid-19-vaccination-eu-eea12:11
BrainstormUpdates for Hong Kong: +8052 cases, +12 deaths since 22 hours ago — Afghanistan: +162 cases since 22 hours ago13:01
BrainstormNew from BMJ Open: Postnatal corticosteroid use for prevention or treatment of bronchopulmonary dysplasia in England and Wales 2012-2019: a retrospective population cohort study: Objective Describe the population of babies who do and do not receive postnatal corticosteroids for prevention or treatment of [... want %more?] → http://bmjopen.bmj.com/cgi/content/short/12/11/e06383514:44
BrainstormNew from r/Coronavirus: Coronavirus: Guangzhou to build 250,000 quarantine beds as China COVID cases rise → https://old.reddit.com/r/Coronavirus/comments/yxq8y3/guangzhou_to_build_250000_quarantine_beds_as/15:13
BrainstormNew from r/COVID19: COVID19: Helminth exposure protects against murine SARS-CoV-2 infection through macrophage dependent T cell activation → https://old.reddit.com/r/COVID19/comments/yxrtkt/helminth_exposure_protects_against_murine/15:33
BrainstormUpdates for Malta: +19 cases since 22 hours ago16:02
BrainstormNew from r/COVID19: COVID19: A Potential Role for Zinc to Enhance Treatment for Coronavirus Disease 2019 (COVID-19)? → https://old.reddit.com/r/COVID19/comments/yxt1kd/a_potential_role_for_zinc_to_enhance_treatment/16:32
BrainstormNew from Reddit (test): nCoV: COVID-19 lockdown chaos sets off a rare protest in a Chinese city | 17NOV22 → https://old.reddit.com/r/nCoV/comments/yxte18/covid19_lockdown_chaos_sets_off_a_rare_protest_in/16:42
BrainstormNew from ClinicalTrials.gov: Severe Acute Respiratory Infections (SARI) in Belgium (2011-2020): Conditions :    Influenza Viral Infections;   Respiratory Viral Infection;   Severe Acute Respiratory Infection → https://clinicaltrials.gov/ct2/show/NCT0562095317:03
BrainstormNew from ClinicalTrials.gov: (news): Study to Evaluate Pharmacokinetics, Safety & Tolerability of 101-PGC-005 in Healthy, Adult, Human Subjects → https://clinicaltrials.gov/ct2/show/NCT0561977017:12
BrainstormNew from ClinicalTrials.gov: (news): The Potential Role of sRAGE, KL-6, and SP-D as Prognostic Factors in Children With SARS-CoV-2 → https://clinicaltrials.gov/ct2/show/NCT0561964017:42
BrainstormNew from ClinicalTrials.gov: (translated) Myocardial Protection in Patients With Post-acute Inflammatory Cardiac Involvement Due to COVID-19: Conditions: Myocardial Inflammation; Remodeling, Left Ventricle; Remodeling, Vascular; Left Ventricular Dysfunction; Exercise Intolerance → https://clinicaltrials.gov/ct2/show/NCT0561965318:02
BrainstormUpdates for Chile: +6904 cases, +50 deaths since a day ago18:07
BrainstormNew from ClinicalTrials.gov: (news): Message Communicating Latest Data on COVID Transmission in Patient's Area → https://clinicaltrials.gov/ct2/show/NCT0562122618:12
BrainstormNew from ClinicalTrials.gov: (news): Study of RAY1216 Tablets Compared With Placebo in Patients With Mild to Moderate SARS-CoV-2 Infection → https://clinicaltrials.gov/ct2/show/NCT0562016018:22
BrainstormNew from ClinicalTrials.gov: (news): Acute Rehabilitation in Patients With COVID-19 Pneumonia → https://clinicaltrials.gov/ct2/show/NCT0561966618:32
LjL%print https://twitter.com/1goodtern/status/159313545262180352018:40
LjLlook at this chart18:40
BrainstormLjL, It says: tern on Twitter: "If you haven't been infected, you really want to avoid being infected. If you've been infected once, you *really* want to avoid being infected twice. If you've been infected twice, you **really** want to avoid being infected three times. https://t.co/nXmvEa6gLt" / Twitter18:40
LjLalso18:41
LjL%print https://twitter.com/MiriamHart/status/159319640074528768118:41
BrainstormLjL, It says: Miriam Hart on Twitter: "@BrainstormBot @mike_t_wright @EricTopol @moderna_tx Yes. Have a look at what they recently submitted to FDA Panel. Once you have 3 doses of Novavax (or MRNA then Novavax) you end up with very high Omicron antibodies that don’t wane at 6 months." / Twitter18:41
LjLcan confirm or debunk?18:41
BrainstormNew from ClinicalTrials.gov: (news): A Study to Understand is the COVID-19 Vaccine BNT162b2 is Safe in Indonesia People → https://clinicaltrials.gov/ct2/show/NCT0562123918:42
LjLalso how to compare antibodies from different studies?18:42
BrainstormNew from r/COVID19: COVID19: Exhaled Breath Aerosol Shedding by Highly Transmissible Versus Prior SARS-CoV-2 Variants → https://old.reddit.com/r/COVID19/comments/yxx166/exhaled_breath_aerosol_shedding_by_highly/19:11
BrainstormUpdates for Malaysia: +3457 cases, +9 deaths since 22 hours ago — United Kingdom: +666 deaths since 16 hours ago20:05
BrainstormNew from ProPublica: Michigan’s Largest Utility Wants a Rate Hike as It Disconnects a High Number of Customers for Nonpayment: by Sarah Alvarez , Outlier Media , and Emily Hopkins , ProPublica This article was produced for ProPublica’s Local Reporting Network in partnership with [... want %more?] → https://www.propublica.org/article/dte-energy-michigan-rate-hike-disconnection-nonpayment20:38
BrainstormUpdates for Canada: +5321 cases, +121 deaths since 21 hours ago — North Macedonia: +189 cases, +3 deaths since 7 days ago21:01
BrainstormNew from CIDRAP: Jim Wappes: Study: Severe COVID less likely in kids of vaccinated parents → https://www.cidrap.umn.edu/news-perspective/2022/11/study-severe-covid-less-likely-kids-vaccinated-parents21:17
de-factoLjL, I have seen such claims that severeness of complications with COVID increases with the number of infections, yet i always wonder how much cofunding factors are selected by the cohorts, e.g. if they really are equally comparable21:41
de-factocant they remove all participants that did not have 3 infections from the cohort and only compare the side effects history of those that happen to have had 3 infections (relative per individual)21:42
LjLall the claims i've seen come from the same US Veterans study21:43
LjLso yeah that's your cohorts21:43
LjLit was criticized in the preprint21:43
LjLit's also published on Nature now21:44
de-factobecause for example how to exclude this scenario: assuming (idk just for the Gedankenexperiment) in general side effects become less severe with each infection because the immune system becomes more adept in dealing with the pathogen (in general for the majority of cases). then also assuming some minority of cases are the exception to that rule (e.g. them developing increasingly more auto-immune related issues etc)21:44
LjLand a cohort of old people is kind of the cohort we should be most worrying about imo21:44
LjLi don't understand what you mean21:44
de-factowould that not result in a picture where there is an increased bias with each additional infection to choose those that have a symptomatic (severe) infection, hence are recruited from that minority while for a minority of cases it would go mostly mild or possibly asymptomatic (people only test if they feel sick)21:45
BrainstormNew from CIDRAP: Post-COVID epilepsy rare but more common than after flu: Mary Van Beusekom | News Writer | CIDRAP News Nov 17, 2022 COVID-19 patients are 55% more likely to develop epilepsy or seizures within 6 months than with flu. → https://www.cidrap.umn.edu/news-perspective/2022/11/post-covid-epilepsy-rare-more-common-after-flu21:46
de-factoi am not saying that this is the case, i am only curious how they exclude such possible effects (that the more severe infections are choosen with increased probability relative to the mild or asymptomatic cases with each additional infection)21:46
de-factobasically: how to exclude that there are cofounding selectors affecting the inclusion for each additional infection?21:48
BrainstormUpdates for France: +33331 cases, +87 deaths since 23 hours ago22:03
BrainstormNew from New Scientist: Psychedelic drugs may reopen critical learning periods in the brain: In adult mice, psychedelic drugs including LSD, ketamine and psilocybin have been shown to reopen the brain to a critical window for social learning usually only seen [... want %more?] → https://www.newscientist.com/article/2347662-psychedelic-drugs-may-reopen-critical-learning-periods-in-the-brain/22:06
LjL<Brainstorm> New from r/WorldNews: worldnews: Big Pharma may have to reveal government deals in WHO's draft pandemic rules → https://www.reddit.com/r/worldnews/comments/yy1onx/big_pharma_may_have_to_reveal_government_deals_in/22:51
BrainstormUpdates for Hokkaido, Japan: +22004 cases, +47 deaths since 2 days ago — Tokyo, Japan: +21849 cases, +6 deaths since 2 days ago — Kanagawa, Japan: +12777 cases since 2 days ago — Aichi, Japan: +12446 cases since 2 days ago22:59
BrainstormNew from r/Science: science: Vaccine doubles brain tumour survival rate in medical breakthrough → https://old.reddit.com/r/science/comments/yy2651/vaccine_doubles_brain_tumour_survival_rate_in/23:03

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