libera/##covid-19/ Monday, 2022-04-11

LjLYes but AIDS doesn't really occur if you manage to keep your viral load undetectable with antivirals, and that can be accomplished for many people these days00:00
LjLOf course there are always exceptions as well as people who get unbearable side effects from the antiviraals00:00
BrainstormNew from Reddit (test): nCoV: Fauci warns in-door mask mandates might make a comeback if COVID-19 cases spike | 10APR22 → https://old.reddit.com/r/nCoV/comments/u0ryot/fauci_warns_indoor_mask_mandates_might_make_a/00:01
wakeuphttps://www.livescience.com/third-person-cured-hiv-stem-cell-transplant-from-cord-blood00:05
wakeupit says that a 3rd person was cured00:05
wakeupin all these years, only 3 people were fully cured from AIDS00:05
wakeupand it seems that you need to go through a painful procedure for that to happen00:05
wakeupat least that's what that article seems to suggest00:05
wakeupI don't really know how these people were cured00:06
wakeupbut well some slow progress towards the cure maybe is being made00:06
wakeuplike for covid... I thought that vaccine would prevent people from feeling bad... my brother was vaccinated and he still felt bad because of the covid, not as much as me, but still00:07
LjLThose people underwent that procedure because they had cancers. The procedure is too dangerous to use it to cure regular patients00:07
LjLBut yes, maybe some progress will be made from it00:07
LjLThe vaccine prevented most people from feeling bad before Omicron00:08
wakeupso people that feel bad from covid it's because they caught that variant00:09
wakeup?00:09
LjLEveryone is catching that variant now00:12
LjLDelta is pretty much gone00:12
BrainstormUpdates for Germany: +45149 cases since 23 hours ago01:02
BrainstormNew from COVID on Twitter: Marc Veldhoen (@Marc_Veld): "These findings suggest that fluvoxamine, a widely available and inexpensive treatment for outpatients with COVID-19, was associated with a reduction in hospitalizations." pic.twitter.com/jTYlwYCFrn → https://twitter.com/Marc_Veld/status/151330284699699200901:55
BrainstormNew from COVID on Twitter: Ameet Chimote (@ameetchimote): The next leap in coronavirus vaccine development could be a nasal spray- congrats  @VirusesImmunity  for your lab’s research on intranasally delivered vaccines in this article.  washingtonpost.com/health/2022/04… → https://twitter.com/ameetchimote/status/151331277293484851202:44
BrainstormNew from COVID on Twitter: Prof. Akiko Iwasaki (@VirusesImmunity): An excellent piece on why we should be looking to nasal spray as the future of COVID booster vaccines by @Carolynyjohnson @NIAIDNews please include our Prime and Spike in the upcoming vaccine bake-off  washingtonpost.com/health/2022/04… → https://twitter.com/VirusesImmunity/status/151331730425116262402:54
BrainstormNew from COVID on Twitter: Scott Gottlieb, MD (@ScottGottliebMD): Shanghai Government has disclosed 130,000 covid infections, and said there’s been one severe case and no deathsIt’s an implausible set of figures contradicted by reporting in @wsj and other outlets, where outbreaks in nursing homes, and [... want %more?] → https://twitter.com/ScottGottliebMD/status/151334819416757863004:58
BrainstormUpdates for Australia: +43946 cases, +5 deaths, +90612 tests since 19 hours ago05:00
BrainstormNew from r/COVID19: COVID19: Both COVID-19 infection and vaccination induce high-affinity cross-clade responses to SARS-CoV-2 variants → https://old.reddit.com/r/COVID19/comments/u0z6vt/both_covid19_infection_and_vaccination_induce/06:24
BrainstormUpdates for Japan: +47876 cases, +35 deaths, +67008 tests since a day ago07:06
BrainstormUpdates for China: +26992 cases, +65 deaths since a day ago — Unknown, China: +24804 cases since a day ago — Tokyo, Japan: +8026 cases since a day ago — Kanagawa, Japan: +4098 cases, +5 deaths since a day ago08:02
BrainstormNew from Reddit (test): CoronaVirus_2019_nCoV: WHO Warns About The New Covid Variant XE , this new variety is a mutant hybrid of the two prior Omicron variants, BA.1 and BA.2 → https://old.reddit.com/r/CoronaVirus_2019_nCoV/comments/u10du9/who_warns_about_the_new_covid_variant_xe_this_new/08:58
BrainstormNew from r/Coronavirus: Daily Discussion Thread | April 11, 2022: Please refer to our Wiki for more information on COVID-19 and our sub. You can find answers to frequently asked questions in our FAQ , where there is valuable information such as our: → https://old.reddit.com/r/Coronavirus/comments/u11nt3/daily_discussion_thread_april_11_2022/09:08
BrainstormNew from Reddit (test): Something I didn't know about vaccinations for children.: I took my daughter for a vacation yesterday and when we were going through the standard questionnaire and I said my daughter had had covid at the beginning of March the person told me my [... want %more?] → https://old.reddit.com/r/CoronavirusUK/comments/u11pjz/something_i_didnt_know_about_vaccinations_for/09:28
BrainstormUpdates for Taiwan: +630 cases, +50528 tests since a day ago10:01
BrainstormNew from BioNTech: BioNTech Presents Positive Preliminary Phase 1/2 Data for First-in-Class CAR-T Program BNT211 at AACR: BNT211 combines two innovative approaches in one regimen, an autologous CAR-T cell therapy targeting the oncofetal antigen [... want %more?] → https://investors.biontech.de/news-releases/news-release-details/biontech-presents-positive-preliminary-phase-12-data-first-class10:06
BrainstormNew from StatNews: Opinion: The ‘successful failures’ of Apollo 13 and Covid-19 vaccination: Doomed from the start. That phrase neatly describes the Apollo 13 mission as well as the ongoing Covid-19 vaccination effort in the U.S. Yet both can be seen as "successful… → https://www.statnews.com/2022/04/11/successful-failures-apollo-13-covid-19-vaccination/10:46
BrainstormNew from BMJ: COVID-19: Risk of adverse events after covid-19 in Danish children and adolescents and effectiveness of BNT162b2 in adolescents: cohort study → http://www.bmj.com/content/377/bmj-2021-068898.short11:35
BrainstormNew from BBC Health: Wales' unpaid carers to get a break through £9m fund: The cash aims to help relieve the pressure on carers after the "added stress" of the Covid pandemic. → https://www.bbc.co.uk/news/uk-wales-6104009212:14
BrainstormNew from Pfizer: Pfizer Names David M. Denton Chief Financial Officer:  Anonymous (not verified) Mon, 04/11/2022 - 06:45 Monday, April 11, 2022 - 06:45am NEW YORK--(BUSINESS WIRE)--Pfizer Inc. (NYSE: PFE) today announced that David M. Denton will join the [... want %more?] → https://www.pfizer.com/news/press-release/press-release-detail/pfizer-names-david-m-denton-chief-financial-officer12:54
BrainstormNew from BioNTech: BioNTech and Matinas BioPharma Announce Exclusive Research Collaboration to Evaluate Novel Delivery Technology for mRNA-based Vaccines: Exclusive collaboration combines BioNTech’s mRNA vaccine development expertise and Matinas’ [... want %more?] → https://investors.biontech.de/news-releases/news-release-details/biontech-and-matinas-biopharma-announce-exclusive-research13:04
BrainstormNew from BMJ: Covid-19: Hospital and ambulance services struggle with huge demand and staff illness: Hospitals and ambulance services in England are facing “extreme pressures” and a high volume of staff absences, forcing some to declare critical incidents and others to warn of 12 hour waits for... → http://www.bmj.com/content/377/bmj.o950.short13:33
BrainstormNew from r/COVID19: Weekly Scientific Discussion Thread - April 11, 2022: This weekly thread is for scientific discussion pertaining to COVID-19. Please post questions about the science of this virus and disease here to collect them for others and clear up post space for [... want %more?] → https://old.reddit.com/r/COVID19/comments/u1633r/weekly_scientific_discussion_thread_april_11_2022/14:02
BrainstormNew from COVID on Twitter: Squawk Box (@SquawkCNBC): "Shanghai has one of the largest oldest urban populations...about 50% of the people over the age of 80 in Shanghai haven't had 2 or more doses of vaccine," says @ScottGottliebMD. "The mitigation seems to be the ends in and of themselves and they haven't used that [... want %more?] → https://twitter.com/SquawkCNBC/status/151348785952481689614:12
BrainstormNew from COVID on Twitter: Squawk Box (@SquawkCNBC): "Right now you have about 23 cities in China under some form of lockdown covering about 200M people. It appears they've lost control of this in #Shanghai. There's many more infections than what's being reported. The data coming out of there is implausible," says [... want %more?] → https://twitter.com/SquawkCNBC/status/151348904913428070714:22
BrainstormNew from Contagion Live: V-safe + VAERS Data Affirm COVID-19 Vaccine Safety: Adding v-safe active monitoring to VAERS passive reporting produced "most comprehensive" program, and affirmed COVID-19 vaccine safety. → https://www.contagionlive.com/view/v-safe-vaers-data-affirm-covid-19-vaccine-safety14:42
BrainstormNew from Reddit (test): Covid2019: COVID-19 May Increase Risk of Type 2 Diabetes: With more than 80 million cases in the U.S., between 800,000 and 1.6 million people could develop type 2 diabetes that may not have had the condition otherwise → https://old.reddit.com/r/Covid2019/comments/u16xp8/covid19_may_increase_risk_of_type_2_diabetes_with/14:52
BrainstormNew from Reddit (test): nCoV: Global COVID Cases For 11APR22 → https://old.reddit.com/r/nCoV/comments/u17800/global_covid_cases_for_11apr22/15:02
BrainstormNew from COVID on Twitter: Jeffrey Barrett (@jcbarret): BA.2 up to 97% in the most recent sequences, completing the SGTF alternation pattern for every variant sweep in the UK. Could it switch a 6th time? Only two sequences in the UK so far, but   mutations in the BA.4 description from the most recent @UKHSA tech [... want %more?] → https://twitter.com/jcbarret/status/151350579829448704515:21
BrainstormNew from Reddit (test): nCoV: China's Covid outbreak worsens as Shanghai cases top 26,000 | 11APR22 → https://old.reddit.com/r/nCoV/comments/u185yf/chinas_covid_outbreak_worsens_as_shanghai_cases/15:50
BrainstormNew from Reddit (test): nCoV: Shanghai discharges thousands of patients, boosts supplies | 10APR22 → https://old.reddit.com/r/nCoV/comments/u18tkb/shanghai_discharges_thousands_of_patients_boosts/16:20
BrainstormNew from COVID on Twitter: Tulio de Oliveira (@Tuliodna): Vaccination remains the key intervention to protect against severe disease, hospitalization and death from all known variants. It is a great time to get a booster and keep the variants at bay and return to normal life. → https://twitter.com/Tuliodna/status/151352997993764045416:59
BrainstormUpdates for Tonga: +513 cases, +14490 tests since 3 days ago17:01
BrainstormNew from Ars Technica: Science: Pythom Space tests its rocket with questionable safety practices → https://arstechnica.com/?p=184712817:09
BrainstormNew from LitCovid: (news): High incidence of COVID-19 at nursing homes in Madrid, Spain, despite preventive measures. → https://www.ncbi.nlm.nih.gov/research/coronavirus/publication/3539748317:29
BrainstormNew from Reddit (test): Covid2019: Akston Biosciences has dosed the first volunteers in a Phase II/III clinical trial of its low cost, shelf-stable, thermostable protein subunit Covid-19 vaccine, AKS-452, in India. → https://old.reddit.com/r/Covid2019/comments/u1bebi/akston_biosciences_has_dosed_the_first_volunteers/18:37
BrainstormNew from Ars Technica: Science: DC’s Gridiron COVID outbreak tally hits 72 as cases tick up nationwide → https://arstechnica.com/?p=184716218:48
Arsaneritonly 72 cases in DC?18:53
BrainstormNew from COVID on Twitter: Bloom Lab (@jbloom_lab): @Tuliodna @tylernstarr @AllieGreaney For comparison, K417N had a decrease of -0.6 on log10 scale, but that was able to fix, although typically only in combination with other affinity enhancing mutations. See data here on affinity effects: jbloomlab.github.io/SARS-CoV-2-RBD… → https://twitter.com/jbloom_lab/status/151356351646822809619:08
BrainstormNew from COVID on Twitter: Bloom Lab (@jbloom_lab): @PeacockFlu @Tuliodna @tylernstarr @AllieGreaney At least in N501Y background, Q493R causes a -0.4 in affinity (log10 scale), so lack of Q493R might provide more affinity buffer for F486V. But these measurements are on N501 or Beta background, and there could be a [... want %more?] → https://twitter.com/jbloom_lab/status/151356503160602214519:17
BrainstormNew from StatNews: After accusations of structural racism at JAMA, a Black health-equity advocate is named the journal’s editor: Kirsten Bibbins-Domingo, a Black internist and epidemiologist at the University of California, San [... want %more?] → https://www.statnews.com/2022/04/11/after-accusations-of-structural-racism-at-jama-a-black-health-equity-advocate-is-named-the-journals-editor/19:47
BrainstormNew from WebMD: Could COVID Increase Your Risk for Shingles?: Researchers found people 50 and older who had COVID were 15% more likely to develop shingles, compared to people who were never infected. → https://www.webmd.com/skin-problems-and-treatments/shingles/news/20220411/could-covid-infection-after-age-50-leave-you-vulnerable-to-shingles19:58
BrainstormUpdates for United Kingdom: +91172 cases, +348 deaths since 2 days ago — Netherlands: +23679 cases, +21 deaths since a day ago — Denmark: +3527 cases, +36 deaths since 2 days ago — France: +99098 cases, +45 deaths since 12 hours ago20:09
BrainstormNew from COVID on Twitter: Scott Gottlieb, MD (@ScottGottliebMD): Many parents with young kids, some with health conditions, feel rightful urgency to access a covid vaccine and I share their concerns.The observation I offered here is only my analysis of how the regulatory process could unfold. I hope things [... want %more?] → https://twitter.com/ScottGottliebMD/status/151358137626782515720:17
BrainstormNew from COVID on Twitter: Eric Topol (@EricTopol): Myocarditis from Covid in hospitalized patients (rare, 2.4/1,000) and a consensus statement/review (including vaccine effect) in children and adolescents ahajournals.org/doi/10.1161/CI…ahajournals.org/doi/10.1161/CI…@CircAHA pic.twitter.com/MkG1hffNLI → https://twitter.com/EricTopol/status/151358311007135744220:27
BrainstormNew from COVID on Twitter: Eric Topol (@EricTopol): The marked inter-individual variability in response to #SARSCoV2 and Covid is, in part, related to genetics. A succinct summary of the known genomic loci that are associated with both risk and protection nature.com/articles/s4158…@NatureGenet by @tomhemmingk [... want %more?] → https://twitter.com/EricTopol/status/151358674992191897820:46
BrainstormUpdates for Italy: +28705 cases, +192782 tests since a day ago20:59
BrainstormNew from COVID on Twitter: Baric Laboratory (@Baric_Lab): We are looking for Postdocs to study RNA viral pathogenesis, vaccines and therapeutics @UNCpublichealth #jobs #postdocjobs #coronavirus #SARSCoV2 #COVID19 unc.peopleadmin.com/postings/198657 pic.twitter.com/BZKFp4PBTO → https://twitter.com/Baric_Lab/status/151359295526899712521:06
BrainstormNew from COVID on Twitter: Timothy Sheahan (@timothysheahan): We are looking for #postdocs to study #RNAvirus pathogenesis and therapeutic development #academia #jobs #SARSCoV2 #COVID19 @UNCpublichealth pic.twitter.com/7hri6PccEK → https://twitter.com/timothysheahan/status/151359382357796864821:16
BrainstormNew from CIDRAP: News Scan for Apr 11, 2022: COVID-19 and elder mental health Risk factors for COVID-related syndrome H5N6 avian flu case in China Global flu rebound Polio in Africa → https://www.cidrap.umn.edu/news-perspective/2022/04/news-scan-apr-11-202221:25
BrainstormNew from COVID on Twitter: On this day in the biocentury (@OTD_biocentury): OTD 2005 Maurice Hillman died. Arguably saved more lives than any other pharma scientist. At Merck led development of vaccines for measles, mumps, hepatitis A, hepatitis B, chickenpox, meningitis, pneumonia and Haemophilus influenzae [... want %more?] → https://twitter.com/OTD_biocentury/status/151360297445462426021:55
BrainstormUpdates for Canada: +11222 cases, +41 deaths since a day ago22:02
BrainstormNew from COVID19 Vaccine Tracker: (translated) valerie: AnGes: AG0302-COVID19 → https://covid19.trackvaccines.org/vaccines/31/22:05
BrainstormNew from COVID19 Vaccine Tracker: valerie: Aivita Biomedical Inc: AV-COVID-19 → https://covid19.trackvaccines.org/vaccines/74/22:24
BrainstormNew from COVID on Twitter: Tom Wenseleers (@TWenseleers): Nice summary on what to expect in terms of further evolution of SARS-CoV2 in the thread of @trvrb below. twitter.com/trvrb/status/1… → https://twitter.com/TWenseleers/status/151361925306845593622:52
BrainstormUpdates for Germany: +92639 cases since 22 hours ago — France: +124590 cases, +223 deaths since 15 hours ago23:11
BrainstormNew from CIDRAP: Shanghai tweaks lockdown as COVID-19 surge presses on: Lisa Schnirring | News Editor | CIDRAP News Apr 11, 2022 Also, Philadelphia reinstates a mask mandate, the first major US city to do so. → https://www.cidrap.umn.edu/news-perspective/2022/04/shanghai-tweaks-lockdown-covid-19-surge-presses23:12
BrainstormNew from COVID on Twitter: Marc Veldhoen (@Marc_Veld): Understanding COVID-19 through genome-wide association studiesWhy do people respond diverse to infections and different to distinctive pathogens? It is all about genetics!nature.com/articles/s4158… → https://twitter.com/Marc_Veld/status/151363407717329305723:51

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