libera/##covid-19/ Thursday, 2022-03-17

BrainstormUpdates for Germany: +110599 cases, +298 deaths since 8 hours ago00:00
BrainstormNew from The Lancet (Online): [Articles] Comparative analysis of the risks of hospitalisation and death associated with SARS-CoV-2 omicron (B.1.1.529) and delta (B.1.617.2) variants in England: a cohort study: The risk of severe outcomes following SARS-CoV-2 infection is substantially lower [... want %more?] → https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(22)00462-7/fulltext00:32
BrainstormNew from Ars Technica: Science: COVID cases are again on the rise globally as testing, health measures decline → https://arstechnica.com/?p=184172501:01
LjLbut it's okay because nobody caaaaares anymore01:04
LjLwe can just not care, it's almost like the deaths don't happen, unless it's you or someone you know or it affects global available workforce01:05
LjLbut at least that last economic factor can be confounded greatly by more visible issues such as, say, a war in progress01:05
BrainstormUpdates for Benin: +377 cases since 13 days ago — France: +111923 cases since 9 hours ago — Canada: +7287 cases since 9 hours ago — United Kingdom: +91418 cases since 9 hours ago01:09
oerheksLjL, this diabetes thingy does not hit the news  https://twitter.com/EricTopol/status/150421709000524185601:11
oerheksit is as covid wipes out most of the people with under lying conditions..01:11
LjLwut01:12
LjLcan you explain why you think that's what it means01:12
LjLthis is potentially important, and i had heard about it before, though i was probably negligent and didn't particularly add it to zotero, but... what this is saying, on its face, is that people "predominantly mild" COVID (so not "wiped out") develop diabetes at higher rates than people who had other respiratory disease that are not COVID (i.e. people who could be "wiped out" if they're weak anyway, because they did also have a respiratory disease)01:14
LjLso the suggestion is that there is a causal relationship, COVID causing increased diabetes rates01:15
oerheksoke, wiped out is a bit too strong.01:15
LjLif you read it differently let me know how because that's how the authors read it and also how it comes across to me01:15
BrainstormNew from BMJ Open: Usual source of primary care and preventive care measures in the COVID-19 pandemic: a nationwide cross-sectional study in Japan: Objectives To assess multiple preventive care measures and to examine their associations with having a usual source of primary care and primary care performance during the [... want %more?] → http://bmjopen.bmj.com/cgi/content/short/12/3/e05741801:49
BrainstormNew from COVID on Twitter: Eric Topol (@EricTopol): Adding Vietnam as a comparator, 3 places (+ Hong Kong) w/ minimal Prior Covid and pronounced Omicron case surges Hong Kong w/ extreme fatality rate, first signs of slowingVietnam's level of protection is impressive despite less vaccine coverage than South [... want %more?] → https://twitter.com/EricTopol/status/150426019680099532901:58
BrainstormUpdates for Malaysia: +28298 cases, +105 deaths since 10 hours ago — Slovakia: +13652 cases since 10 hours ago02:00
BrainstormNew from COVID on Twitter: Michael Lin, MD PhD  (@michaelzlin): And out in NEJM today is the Israeli study on a 4th Pfizer dose vs Omicron.Dose 4 restores the 30% VE of dose 3 only.Recall we used to require 50% VE for approval.Sure a 4th dose is needed *if no other options exist* but we should demand better [... want %more?] → https://twitter.com/michaelzlin/status/150426509328601907602:18
BrainstormNew from COVID on Twitter: Michael Lin, MD PhD  (@michaelzlin): When these results were previewed 2 months ago, I wrote it meant it was time to update the formulation with extant viral sequences. Pfizer boasted they could do it by March. I felt that was more a PR move than a serious commitment.twitter.com/michaelzlin/st… → https://twitter.com/michaelzlin/status/150426730930046566602:27
BrainstormNew from COVID on Twitter: Scott Gottlieb, MD (@ScottGottliebMD): 1.19% of South Korea’s population tests positive for COVID in one day twitter.com/bnodesk/status… → https://twitter.com/ScottGottliebMD/status/150426814502817382502:37
LjL%title https://pandem-ic.com/the-surge-in-south-korea-is-completely-unparalleled/  these graphs here02:44
BrainstormLjL: From pandem-ic.com: The surge in South Korea is completely unparalleled02:44
BrainstormNew from COVID on Twitter: Michael Lin, MD PhD  (@michaelzlin): I had predicted summer approval for new boosters. That's consistent with Pfizer proposing a 4th shot of ye olde formula as a stopgap for waning immunity now.But it would be nice if companies and FDA can commit to a real timeline for Omicron booster [... want %more?] → https://twitter.com/michaelzlin/status/150427052993447936002:46
BrainstormNew from ##covid-19 Zotero group: Pandem-ic: Type Web Page URL https://pandem-ic.com/ Accessed 2022-03-17 01:48:33 Language en-US Abstract Data analytics on pandemic outcomes and solutions across countries → https://www.zotero.org/groups/covid_links/items/RA44ATTZ02:56
BrainstormNew from COVID on Twitter: Michael Lin, MD PhD  (@michaelzlin): It's exceedingly unlikely that unboosted uninfected 1xJ&J can more effective than unboosted uninfected 2xRNA vs Omicron because all the evidence is their nAbs are far lower. I covered this earliertwitter.com/michaelzlin/st… pic.twitter.com/RlcCmt5t8t → https://twitter.com/michaelzlin/status/150428040734004428903:24
BrainstormNew from COVID on Twitter: Michael Lin, MD PhD  (@michaelzlin): Not to mention, as we knew, that JNJ x1 (Ad26 here) as an initial "vaccine" is far inferior in anti-Omicron antibodies to RNA x2 (BNT2x here), regardless of whether you boost with another RNA or a JNJ dose later. pic.twitter.com/6aFx7H9GCV → https://twitter.com/michaelzlin/status/150428600972222464103:43
BrainstormUpdates for South Korea: +621317 cases, +429 deaths since 12 hours ago — New Zealand: +20092 cases, +10 deaths since 12 hours ago — Cayman Is.: +5 deaths since 4 days ago03:59
BrainstormNew from r/COVID19: COVID19: Efficacy of a Fourth Dose of Covid-19 mRNA Vaccine against Omicron → https://old.reddit.com/r/COVID19/comments/tfzzpy/efficacy_of_a_fourth_dose_of_covid19_mrna_vaccine/04:11
BrainstormNew from Politico: Irish PM Micheál Martin tests positive for COVID while in US to meet Biden: WASHINGTON — Irish Prime Minister Micheál Martin tested positive for COVID on Wednesday night and had to leave the Ireland Funds Gala event, where he was photographed sitting maskless [... want %more?] → https://www.politico.com/news/2022/03/16/ireland-michael-martin-covid-biden-0001803404:53
BrainstormUpdates for Hong Kong: +213662 cases, +279 deaths since 13 hours ago05:08
BrainstormNew from This Week In Virology: TWiV 876: Spillover market with Michael Worobey: Michael Worobey joins TWiV to explain evidence that SARS-CoV-2 emerged via the wildlife trade and that the Huanan market was the unambiguous epicenter of the COVID-19 pandemic. → https://www.microbe.tv/twiv/twiv-876/05:22
LjL%tell Tuvix, de-facto: you might find this site's various graphs interesting https://pandem-ic.com/05:37
BrainstormLjL, I'll pass Tuvix aka Tuvix_, as well as de-facto your message when they are around.05:37
BrainstormNew from Science-Based Medicine: “This Would Translate to About 10,000 Deaths”- Reflections From the Start of the Pandemic: “This would translate to about 10,000 deaths” Two years ago, Dr. John Ioannidis wrote an essay in STAT titled “A Fiasco in The Making? As The Coronavirus Pandemic Takes Hold, We Are Making [... want %more?] → https://sciencebasedmedicine.org/10000-deaths/05:51
BrainstormUpdates for United Kingdom: +93943 cases since 14 hours ago06:10
BrainstormUpdates for Western Australia, Australia: +13196 cases, +2 deaths since 15 hours ago — Germany: +294924 cases since 15 hours ago — Guernsey, United Kingdom: +2219 cases since 6 days ago — Jilin, China: +2198 cases since 15 hours ago07:00
BrainstormNew from COVID on Twitter: Michael Lin, MD PhD  (@michaelzlin): And Putin himself expresses his anti-Westerness, criticizing Russians who mentally "live over there".The tsars emulated the West (and married their royalty). Lenin followed the German Marx.Putin is the first Russian leader in 500 years to shun the [... want %more?] → https://twitter.com/michaelzlin/status/150434012041716121607:16
BrainstormNew from MedicineNet: (news): Pfizer Asks FDA to Approve Second Booster for Seniors → http://www.medicinenet.com/script/main/art.asp07:45
BrainstormNew from r/Coronavirus: Daily Discussion Thread | March 17, 2022: Please refer to our Wiki for more information on COVID-19 and our sub. You can find answers to frequently asked questions in our FAQ , where there is valuable information such as our: → https://old.reddit.com/r/Coronavirus/comments/tg46z0/daily_discussion_thread_march_17_2022/08:05
BrainstormNew from COVID on Twitter: Michael Lin, MD PhD  (@michaelzlin): Omcron vs Delta: "larger reduction in intrinsic severity (in unvaccinated individuals) counterbalanced by a reduction in vaccine effectiveness."thelancet.com/journals/lance… → https://twitter.com/michaelzlin/status/150435628004285644808:25
BrainstormNew from COVID on Twitter: Michael Lin, MD PhD  (@michaelzlin): My deductions above that Omicron is intrinsically milder than Delta proved correct, although the number of infections still made the Omicron wave the deadliest in many places, unfortunately.twitter.com/michaelzlin/st… → https://twitter.com/michaelzlin/status/150435995343946547408:44
BrainstormNew from COVID on Twitter: Marc Veldhoen (@Marc_Veld): The Brownstone Institute vs. “vaccine fanatics” in The Epoch Times respectfulinsolence.com/2022/03/16/the… → https://twitter.com/Marc_Veld/status/150436356601044582608:53
BrainstormNew from COVID on Twitter: Gunhild Alvik Nyborg (@GANyborg): So Denmark has lost it completely. Will Norway follow in this delusional madness? Are there no medical doctors or immunologists there to tell decision makers that Covid IS NOT A COMMON COLD?The world has indeed gone mad. Those supposed to protect public [... want %more?] → https://twitter.com/GANyborg/status/150437044505478758409:22
BrainstormNew from COVID on Twitter: Marc Veldhoen (@Marc_Veld): More antibodies, more neutralisation to all variants. VE een extra 30%. Better prevention symptomatic disease. "Our data provide evidence that a fourth dose of mRNA vaccine is immunogenic, safe, and somewhat efficacious (primarily against symptomatic disease)." → https://twitter.com/Marc_Veld/status/150437322396164096409:31
BrainstormNew from StatNews: Health: With infections spiking in Europe and a variant on the rise, experts warn the U.S. could face a Covid resurgence → https://www.statnews.com/2022/03/17/ba2-variant-experts-warn-covid-resurgence/09:41
BrainstormNew from COVID on Twitter: Gunhild Alvik Nyborg (@GANyborg): UK is also axing funding for the REACT study that is only funded throughout March. That means the two best data providers will no longer shine the light on what’s going on with the pandemic. Seems the world will be fumbling in the dark soon now [... want %more?] → https://twitter.com/GANyborg/status/150437973695649382410:00
BrainstormNew from EMA: What's new: Orphan: Orphan designation: Human IgG1 monoclonal antibody against alpha-synuclein, Treatment of multiple system atrophy, 20/05/2021, Positive → https://www.ema.europa.eu/en/medicines/human/orphan-designations/eu-3-21-243110:58
BrainstormUpdates for Tonga: +458 cases, +12070 tests since 19 hours ago11:11
rpifanso ive had to get antibotics once again11:28
BrainstormNew from BMJ: Climate, pandemic, and war: an uncontrolled multicrisis of existential proportions: In the heat of the pandemic we parked our response to climate change. In the heat of Russia’s war on Ukraine the pandemic and climate change now take a back seat. That’s inevitable to some degree,... → http://www.bmj.com/content/376/bmj.o689.short11:36
BrainstormNew from COVID on Twitter: Marc Veldhoen (@Marc_Veld): As reported previously, with limited numbers, but in adults and children, SARS-CoV-2 infection can increase the risk of diabetes.Incidence of newly diagnosed diabetes after Covid-19link.springer.com/article/10.100… pic.twitter.com/BPh08iNw9g → https://twitter.com/Marc_Veld/status/150440643157083750711:46
BrainstormNew from Politico: French senators slam consultancy use ‘explosion’ under Macron: Consultancy firms have been paid billions to advise on policies from coronavirus vaccinations to France’s EU presidency. → https://www.politico.eu/article/french-senators-slam-consultancy-use-explosion-under-macron/11:55
BrainstormUpdates for United Kingdom: +93946 cases since 20 hours ago12:01
BrainstormNew from ECDC: Data on country response measures to COVID-19: This downloadable data file contains information on non-pharmaceutical interventions (or response measures)  that countries in the EU/EEA have reported to date. → https://www.ecdc.europa.eu/en/publications-data/download-data-response-measures-covid-1912:25
BrainstormNew from Reddit (test): China_Flu: Melatonin as adjunctive therapy in patients admitted to the Covid-19 → https://old.reddit.com/r/China_Flu/comments/tg8xgi/melatonin_as_adjunctive_therapy_in_patients/13:33
BrainstormNew from StatNews: Ashish Jha to replace Jeff Zients as White House Covid response coordinator: Biden is replacing Covid response coordinator Jeff Zients with Ashish Jha, the White House announced Thursday morning. → https://www.statnews.com/2022/03/17/ashish-jha-replace-jeff-zients-covid-coordinator/14:02
BrainstormNew from COVID on Twitter: Scott Gottlieb, MD (@ScottGottliebMD):  Jeff Zients was the right person in the right place at the right time. He got us through a hard period of Covid by leveraging his deep expertise in using the tools of government to advance health.He took on an impossible task and made a [... want %more?] → https://twitter.com/ScottGottliebMD/status/150444438628062413814:14
BrainstormNew from EMA: What's new: Medicine: Veterinary medicines European public assessment report (EPAR): Purevax FeLV, vaccine against feline leukaemia, Date of authorisation: 13/04/2000, Revision: 12, Status: Authorised → https://www.ema.europa.eu/en/medicines/veterinary/EPAR/purevax-felv14:24
BrainstormNew from StatNews: Pharma: STAT+: Pharmalittle: Biogen Alzheimer’s data is published in little-known journal; WHO may reject Medicago Covid shot over ties to Philip Morris → https://www.statnews.com/pharmalot/2022/03/17/covid19-vaccine-alzheimers-biogen-patents-gilead-sanofi-who/14:35
BrainstormNew from EMA: Human medicine assessment reports: (news): Human medicines European public assessment report (EPAR): Nuvaxovid, COVID-19 Vaccine (recombinant, adjuvanted), COVID-19 virus infection, Date of authorisation: 20/12/2021, Revision: 1, Status: Authorised → https://www.ema.europa.eu/en/medicines/human/EPAR/nuvaxovid14:54
BrainstormUpdates for Germany: +299489 cases since 23 hours ago — Vanuatu: +87 cases since 23 hours ago15:02
BrainstormNew from r/COVID19: COVID19: Antibody durability at 1 year after Sputnik V vaccination → https://old.reddit.com/r/COVID19/comments/tgaur4/antibody_durability_at_1_year_after_sputnik_v/15:04
BrainstormNew from COVID on Twitter: Andy Slavitt  (@ASlavitt): NEWS: @ashishkjha will be the new White House lead of the COVID response. He’s an extraordinary person to advice the president & keep the country safe & moving forward. 1/ → https://twitter.com/ASlavitt/status/150445939532892979415:23
BrainstormNew from r/COVID19: COVID19: Evaluating COVID-19 vaccines in the real world → https://old.reddit.com/r/COVID19/comments/tgbdfl/evaluating_covid19_vaccines_in_the_real_world/15:33
BrainstormNew from COVID on Twitter: Eric Topol (@EricTopol): While many countries Europe and Asia-Pacific have Omicron BA.1 and BA.2 breakouts, some countries, like the United States, are cutting funds to prepare, somehow thinking they are immune pic.twitter.com/ZrROXluSqL → https://twitter.com/EricTopol/status/150446666417945396215:43
BrainstormUpdates for Canada: +6577 cases since 23 hours ago15:59
BrainstormNew from LitCovid: Early Treatment with Sotrovimab for Covid-19.: {'title': '', 'date': '2022-03-17T12:00:00Z', '_id': '35294998'} → https://www.ncbi.nlm.nih.gov/research/coronavirus/publication/3529499816:02
BrainstormNew from ClinicalTrials.gov: (news): Effectiveness, Immunogenicity and Safety of the Second Booster Dose of the Vaccine Against COVID-19 in the Elderly → https://clinicaltrials.gov/ct2/show/NCT0528390216:41
BrainstormNew from ClinicalTrials.gov: (news): Immunogenicity and Safety of a Booster Dose of the SpikoGen Vaccine in Kidney Transplant Recipients After Two Doses of Sinopharm Vaccine → https://clinicaltrials.gov/ct2/show/NCT0528538416:52
BrainstormNew from ClinicalTrials.gov: (news): Use of a Combined Regimen of Fluoxetine, Prednisolone and Ivermectin in the Treatment of Mild COVID-19 to Prevent Disease Progression Progression in Papua New Guinea → https://clinicaltrials.gov/ct2/show/NCT0528395417:01
BrainstormNew from COVID on Twitter: Michael Lin, MD PhD  (@michaelzlin): I wasn't going to show the chart from the current study with the invalid Novavax results, because that would give legitimacy to illegitimate results. But since we're talking about it now, here's the chart with the caveats spelled out. pic.twitter.com/HBBBu4mgUf → https://twitter.com/michaelzlin/status/150448972869491507617:12
BrainstormNew from COVID on Twitter: Marc Veldhoen (@Marc_Veld): While additional vax could increase humoral memory in previously naive individuals, it did not recapitulate the distinct CD4+ T cell cytokine profile observed in previously infected subjects. Thus, imprinted features of SARSCoV-2-specific memory lymphocytes [... want %more?] → https://twitter.com/Marc_Veld/status/150449454735892070617:31
BrainstormNew from COVID on Twitter: John Burn-Murdoch (@jburnmurdoch): • And second, despite two years of evidence to the contrary, we continue to attribute to policy what is better understood as people making independent decisions in response to the status of the pandemic, with policy being just one influence.As [... want %more?] → https://twitter.com/jburnmurdoch/status/150449781445329305717:51
BrainstormUpdates for Netherlands: +53791 cases, +19 deaths since 23 hours ago18:10
BrainstormNew from COVID on Twitter: Tom Wenseleers (@TWenseleers): Still anyone's guess what the long-term yearly Covid mortality will be taking into account waning immunity & the evolution of new variants or reappearance of old ones, as that will also depend on how well we do with boosters & updating vaccines (progress [... want %more?] → https://twitter.com/TWenseleers/status/150450487981714637518:11
BrainstormNew from COVID on Twitter: Covid Fact Check UK (@fact_covid): Another great thread from John on the latest COVID-19 situation in the UK and elsewhere. twitter.com/jburnmurdoch/s… → https://twitter.com/fact_covid/status/150450550231058432818:21
BrainstormNew from COVID on Twitter: Eric Topol (@EricTopol): Hello You just got over a wave of the most transmissible #SARSCoV2 variant the world has seen, with the highest level of hospitalizations in the pandemic.Now you are facing a variant w/ 30% more transmissibility, w/o mitigation measures, low vaxx coverage, and [... want %more?] → https://twitter.com/EricTopol/status/150450889387916084718:31
BrainstormNew from COVID on Twitter: Tom Wenseleers (@TWenseleers): Should also say that the advantage of BA.2 appears to be linked to a shorter generation time and perhaps slightly higher contagiousness, but not to immune escape. So we won't get a bit wave of reinfections at least, which is good. twitter.com/kallmemeg/stat… → https://twitter.com/TWenseleers/status/150451351070902273218:50
BrainstormUpdates for Malaysia: +27004 cases, +86 deaths since 17 hours ago — Italy: +82368 cases, +128 deaths, +529882 tests since 23 hours ago19:00
BrainstormNew from COVID on Twitter: Michael Lin, MD PhD  (@michaelzlin): Probably a good thing that the new coronavirus "czar" (not my word choice) actually comes from the health sector.nytimes.com/2022/03/17/us/… → https://twitter.com/michaelzlin/status/150451879535165440319:10
BrainstormNew from WebMD: WHO Predicts COVID Could Still 'Echo Around the World': New reported cases of COVID-19 are up 8% globally, and World Health Organization experts explain what it might mean. → https://www.webmd.com/lung/news/20220317/who-covid-echo-arond-world19:20
BrainstormUpdates for United Kingdom: +93444 cases, +138 deaths since 23 hours ago — Canada: +7623 cases since 23 hours ago20:03
BrainstormNew from WebMD: Postpartum Depression Rates Tripled During the Pandemic: A new study shows rates of postpartum depression rose nearly three-fold during the COVID pandemic, along with increases in major depression and thoughts of self-harm. → https://www.webmd.com/depression/postpartum-depression/news/20220317/postpartum-depression-rates-have-tripled-for-new-moms-during-pandemic20:08
BrainstormUpdates for France: +99348 cases since 20 hours ago22:02

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