libera/##covid-19/ Wednesday, 2022-03-02

BrainstormUpdates for United Kingdom: +99583 cases since 20 hours ago00:02
BrainstormNew from r/COVID19: COVID19: Effect of booster vaccination against Delta and Omicron variants in Iceland → https://old.reddit.com/r/COVID19/comments/t4kxzb/effect_of_booster_vaccination_against_delta_and/00:06
BrainstormNew from COVID on Twitter: Scott Gottlieb, MD (@ScottGottliebMD): In our response to Covid there's much we did right, and things we did wrong; and our collective action to preserve life imposed great hardships even as we still saw 950,000 of our fellow citizens die. The measures created cultural rifts and [... want %more?] → https://twitter.com/ScottGottliebMD/status/149879884620548096600:25
BrainstormUpdates for Hong Kong: +32597 cases, +246 deaths since 23 hours ago — Singapore: +24080 cases, +11 deaths since a day ago — Nicaragua: +101 cases since 6 days ago — Cook Is.: +11 cases since 15 hours ago01:04
BrainstormUpdates for Slovakia: +15437 cases since 23 hours ago — Canada: +3569 cases, +36 deaths, +108260 tests (1.1% positive) since 23 hours ago — France: +93152 cases since 16 hours ago02:07
BrainstormNew from r/Coronavirus: Coronavirus: L.A. County will align with state to end school mask mandate after March 11 → https://old.reddit.com/r/Coronavirus/comments/t4lr1t/la_county_will_align_with_state_to_end_school/02:59
BrainstormNew from r/COVID19: COVID19: SARS-CoV-2 Delta Variant (AY.3) in the Feces of a Domestic Cat → https://old.reddit.com/r/COVID19/comments/t4mevn/sarscov2_delta_variant_ay3_in_the_feces_of_a/03:37
BrainstormUpdates for South Korea: +219237 cases, +96 deaths since a day ago04:09
BrainstormNew from StatNews: In State of the Union, Biden walks a fine line on Covid optimism: President Biden on Tuesday vowed that the U.S. won’t become complacent in its Covid-19 response, even as he attempted to project optimism about returning to normal life. → https://www.statnews.com/2022/03/01/in-state-of-the-union-biden-walks-a-fine-line-on-covid-optimism/04:16
Tuvix^ Yea, I listened to the speech, and found his "technically" correct claim about hospitalizaions weak.04:25
BrainstormNew from COVID on Twitter: Eric Topol (@EricTopol): The new in-pharmacy Covid rapid test and free treatment (Paxlovid) initiative announced by @POTUS tonight is important. We need a much better supply of anti-Covid pills, accurate tests, and solid coordination with pharmacists to pull this off → https://twitter.com/EricTopol/status/149886106584464179504:26
TuvixIt is, technically, true that just considering hospital admits that we're at a level that hasn't been seen since July, but that was _late_ July where we were already well into the uptick of Delta which was very bad for the US. We're *nowhere* near the level of death seen back then (we're doing far worse, have been ever since Delta hit)04:26
TuvixObviously Ukraine is the issue more on people's minds, so it's not really the moment to lean too hard into reminding people that this is still a disease that can land you in the hospital or worse, and yet it still is. Then again, anyone who hasn't been vaccinated or considered that information wouldn't have likely been moved anyway.04:28
TuvixFor context to back the analysis & comparison above, this chart is limited to the "since July" part of Biden's claim, but look at the deaths over that same time: https://ourworldindata.org/explorers/coronavirus-data-explorer?zoomToSelection=true&time=2021-07-24..latest&Metric=Cases%2C+hospital+admissions%2C+ICU+patients%2C+and+deaths&country=~USA04:30
Tuvix(move the start-time of that to get a better ideal of the low point in early-July.04:30
BrainstormNew from ##covid-19 Zotero group: SARS-CoV-2 Delta Variant (AY.3) in the Feces of a Domestic Cat: Type Journal Article Author Olivia C. Lenz Author Andrew D. Marques Author Brendan J. Kelly Author Kyle G. Rodino Author Stephen D. Cole Author Ranawaka A. P. M. Perera Author Susan R. Weiss Author Frederic D. Bushman [... want %more?] → https://www.zotero.org/groups/covid_links/items/CPBTAJSA04:35
LjLhttps://arstechnica.com/science/2022/03/researchers-may-have-ided-first-deer-to-human-sars-cov-2-transmission/04:38
LjLThings got less reassuring when the researchers obtained genomes from some of these samples. All turned out to be distantly related to the rest of the SARS-CoV-2 family tree—roughly as distant from the common ancestor of the pandemic as the omicron variant is. The genomes' closest relatives turned out to be a lineage that had spread from humans to mink in Michigan. The lineage had been identified about a year earlier, but in the intervening time, the lineage ha04:38
LjLd picked up 76 additional mutations—in fact, all the genomes had some small differences from each other.04:38
TuvixWho needs a wet-market when you have infected another mammal?04:39
LjLanother bunch04:40
LjLcats get it, deer get it, and that's probably just all we've paid an ounce to attention to04:40
LjL<apropos> ● [microbio] Omicron-specific mRNA vaccine elicits potent immune responses in mice, hamsters, and nonhuman primates → http://biorxiv.org/cgi/content/short/2022.03.01.481391v1?rss=104:59
BrainstormUpdates for New Zealand: +24106 cases since 23 hours ago — United Kingdom: +99670 cases since 23 hours ago04:59
Alex1138[m]SMH vaccine skeptical deer05:58
BrainstormNew from COVID on Twitter: Scott Gottlieb, MD (@ScottGottliebMD): Reuters: "FDA warns against use of certain unauthorized COVID antigen tests"reuters.com/business/healt… → https://twitter.com/ScottGottliebMD/status/149888729907303629206:11
BrainstormUpdates for Scotland, United Kingdom: +67448 cases, +96 deaths since 23 hours ago — China: +32821 cases since 23 hours ago — Bashkortostan, Russia: +3391 cases, +21 deaths since 23 hours ago — Kedah, Malaysia: +2801 cases, +15 deaths since 23 hours ago07:04
BrainstormNew from r/Coronavirus: Coronavirus: The coronavirus invades cells in the penis and testicles of monkeys, researchers discover → https://old.reddit.com/r/Coronavirus/comments/t4sewv/the_coronavirus_invades_cells_in_the_penis_and/07:17
Cashlin:(07:18
BrainstormNew from MedicineNet: (news): One Big Motivator to Get COVID Vaccine: Travel → http://www.medicinenet.com/script/main/art.asp07:46
BrainstormNew from r/Coronavirus: Daily Discussion Thread | March 02, 2022: Please refer to our Wiki for more information on COVID-19 and our sub. You can find answers to frequently asked questions in our FAQ , where there is valuable information such as our: → https://old.reddit.com/r/Coronavirus/comments/t4v704/daily_discussion_thread_march_02_2022/09:02
BrainstormNew from BMJ: Has the covid pandemic changed the debate about nationalising GPs?: Yes—Azeem MajeedThe intense micromanagement of general practices by NHS England since the start of the covid-19 pandemic has shattered the illusion that NHS GPs are truly “independent.”For example,... → http://www.bmj.com/content/376/bmj.o406.short11:26
BrainstormNew from ECDC: ECDC: Data on the daily number of new reported COVID-19 cases and deaths by EU/EEA country → https://www.ecdc.europa.eu/en/publications-data/data-daily-new-cases-covid-19-eueea-country12:04
BrainstormUpdates for Germany: +182567 cases since 21 hours ago12:04
de-facto%title https://nn.neurology.org/content/9/3/e114613:02
Brainstormde-facto: From nn.neurology.org: Peripheral Neuropathy Evaluations of Patients With Prolonged Long COVID | Neurology Neuroimmunology & Neuroinflammation13:02
de-factoHorrible mistake to expose majorities to this pathogen. As i always said.13:08
TuvixThere was a survey study from Denmark just a couple days ago suggesting lasting symptoms are quite a bit more common than most people believe, and that's at 6 to 12 months after infection.13:12
de-factoallowing SARS-COV-2 to infect majorities of a population may quite well mean making majorities of them unproductive (in terms of mental and physical capacities) and impose a long lasting constant and expensive load on the healthcare system13:33
de-factoas long as there is no cure for long-COVID we cant exclude some damages could be permanent13:34
de-factothis (in my opinion very severe) problem is NOT reflected by official stats only distinguishing between registered infections (in reality there are manyfold more) and fatal outcomes13:35
de-factoi stay with my point, opening transmission paths during a pandemic with a new pathogen that clearly shows signs to induce long lasting damage to even young peoples health is an astronomic mistake.13:36
de-factothere is not sane alternative to ZERO-COVID.13:37
BrainstormNew from Reddit (test): nCoV: Global COVID Cases For 02MAR22 → https://old.reddit.com/r/nCoV/comments/t4z5vj/global_covid_cases_for_02mar22/13:41
undefined_bobI totally agree with you, de-facto13:57
TuvixWell, even too-rosey reports of the stats are commonplace around here. Just this morning a neighboring state official was saying that tourism is ready to attract regional inbound travellers again in his state and stated the improved "metrics." Except hospitalizations & cases are not falling like they did last spring.13:57
TuvixMaybe we'll get to that point where spring & early summer 2022 looks like it did in 2021, but we're not there yet, and we never recovered from Delta most place here in the US; we just got hit with Omicron and now are largely stalled in the recovery from that. On the plus side our hospitals & ICUs are generally not at crisis levels, but that's a pretty low bar to call things back to normal.13:58
BrainstormNew from COVID on Twitter: Scott Gottlieb, MD (@ScottGottliebMD): Good move by Biden Admin to create guaranteed market for rapid tests to ensure large stockpile in event of an unforeseen surge.We need to treat production of tests as a matter of national security and have a large, hot base of preparedness, [... want %more?] → https://twitter.com/ScottGottliebMD/status/149900699768915558414:10
undefined_boband Omicron surged in south africa during their summer14:10
BrainstormNew from Science-Based Medicine: Crizanlizumab for Sickle Cell Crisis: Monoclonal antibodies to prevent sickle cell crisis represents the promise and difficulties of high tech medical treatment. The post  first appeared on Science-Based Medicine . → https://sciencebasedmedicine.org/crizanlizumab-for-sickle-cell-crisis/14:19
TuvixDelta as well, which spread in the US during the global north's summer; in the US the weeks before Delta started to spread saw the lowest case & hospital incidence we'd seen all-pandemic. Winter obviously makes the situation a bit worse, but COVID is clearly not limited to traditionally seasonal waves, making it much different than influenza in that regard.14:19
undefined_bobyeah14:32
BrainstormNew from Reddit (test): CoronaVirus_2019_nCoV: The rapid spread of Omicron BA.2: What studies say - Dr. Lyngse said they found that “vaccinations work in both reducing susceptibility (probability of [acquiring infection]) and infectiousness (probability of [... want %more?] → https://old.reddit.com/r/CoronaVirus_2019_nCoV/comments/t50iyh/the_rapid_spread_of_omicron_ba2_what_studies_say/14:57
BrainstormUpdates for Germany: +184877 cases since 23 hours ago14:59
BrainstormNew from COVID on Twitter: Prof. Akiko Iwasaki (@VirusesImmunity): The beneficial vs. pathogenic roles of T cells in COVID have been noted before. However, the Multiscale PHATE assigned vastly different mortality scores to each T cell subset with distinct effector functions. Seeing this from @mkuchroo was [... want %more?] → https://twitter.com/VirusesImmunity/status/149902286373880217915:07
BrainstormNew from BMJ: Pregnancy and the “presumption of inclusion” in research: It is now almost two years since the UK Obstetric Surveillance System (UKOSS) national study of hospital admission with covid-19 in pregnancy was activated, and 20 months since the first publication... → http://www.bmj.com/content/376/bmj.o559.short15:27
BrainstormNew from r/Science: science: COVID-19: Antibodies derived from natural infection with COVID-19 are more abundant and more potent – at least 10 times more potent – than immunity generated by vaccination alone, according to a study from Oregon Health & Science University [... want %more?] → https://old.reddit.com/r/science/comments/t518iz/covid19_antibodies_derived_from_natural_infection/15:56
BrainstormUpdates for Canada: +26 deaths since 22 hours ago16:02
BrainstormNew from The Atlantic: The CDC Shifted the Pandemic’s Burden to the Vulnerable: This time last week, nearly all Americans were still being urged by the nation’s leadership to please, keep those darn masks on. Then the Great American Unmasking Part Deux began. On Friday, the CDC [... want %more?] → https://www.theatlantic.com/health/archive/2022/03/covid-cdc-guidelines-masks/623337/16:16
BrainstormNew from COVID on Twitter: Scott Gottlieb, MD (@ScottGottliebMD): The Biden Administration's new Covid plan is comprehensive, forward looking, well crafted.It focuses on key capacity building for future contingencies that'll provide greater assurance we're prepared whether Covid remains a low level threat or [... want %more?] → https://twitter.com/ScottGottliebMD/status/149904114777533235316:26
BrainstormNew from COVID on Twitter: Eric Topol (@EricTopol): How Covid directly infects the male genital tract biorxiv.org/content/10.110… whole body PET in non-human primates explains mechanism of erectile dysfunction @HopeLab_NU @NUFeinbergMed @NorthwesternU pic.twitter.com/9Cmd5B2HP0 → https://twitter.com/EricTopol/status/149904526346115072716:36
BrainstormNew from COVID on Twitter: Scott Gottlieb, MD (@ScottGottliebMD): To address new variants and risk Covid takes a more menacing turn, the plan focuses on surveillance through sequencing, wastewater, and regulatory frameworks to allow rapid cycle innovation in drugs, vaccines (likely through reliance on [... want %more?] → https://twitter.com/ScottGottliebMD/status/149904684950799974916:46
BrainstormNew from COVID on Twitter: Scott Gottlieb, MD (@ScottGottliebMD): There’s an appropriate and detailed focus on schools as a priority, preserving in class learning by giving schools more tools and resources to create safer environments when it comes to the risk of spread of respiratory pathogens. Tests, better [... want %more?] → https://twitter.com/ScottGottliebMD/status/149904778617996492816:55
BrainstormUpdates for Germany: +174351 cases, +273 deaths since 23 hours ago17:04
BrainstormNew from COVID on Twitter: Scott Gottlieb, MD (@ScottGottliebMD): There's also lot of emphasis on making a renewed push to extend these capacities to low and middle income countries to help ensure greater equity when it comes to accessing critical public health products (vaccines, oxygen, therapeutics) and [... want %more?] → https://twitter.com/ScottGottliebMD/status/149905027900993536617:05
BrainstormNew from COVID on Twitter: Scott Gottlieb, MD (@ScottGottliebMD): Here is more detail on a national security like emphasis on biosecurity that looks across the range of threats, not just bioterrorism (which had long been the emphasis when these risks were looked at by national security agencies) but also [... want %more?] → https://twitter.com/ScottGottliebMD/status/149905640927049318517:25
BrainstormNew from COVID on Twitter: Eric Topol (@EricTopol): The new US Covid plan released, a 96-page document that addressed many critical unmet needs such as data surveillance, need to counter misinformation, test-to treat, pan-β-coronavirus vaccine, #LongCovid and morenytimes.com/live/2022/03/0…  pic.twitter.com/ei8JipBF4A → https://twitter.com/EricTopol/status/149906010498908570217:35
BrainstormNew from EMA: Human medicine assessment reports: (news): Human medicines European public assessment report (EPAR): Apexxnar, pneumococcal polysaccharide conjugate vaccine (20-valent, adsorbed), Pneumococcal Infections, Date of authorisation: 14/02/2022, Status: Authorised → https://www.ema.europa.eu/en/medicines/human/EPAR/apexxnar17:54
suenoguess Gottlieb is the most optimist than Topol now18:07
BrainstormNew from WebMD: Menstrual Cycle Changes After COVID Vaccine Are Temporary: Two international studies confirm potential menstrual changes associated with getting a COVID vaccine are typically minor and temporary. → https://www.webmd.com/women/pms/news/20220127/any-change-to-menstrual-cycle-after-covid-vaccine-is-minor-temporary-studies18:33
BrainstormNew from StatNews: As Omicron recedes, White House shifts to a more targeted Covid strategy: The Omicron variant is receding, and Americans are returning to everyday life. But the White House isn’t done with its Covid response just yet. → https://www.statnews.com/2022/03/02/as-omicron-recedes-white-house-shifts-to-a-more-targeted-covid-strategy/18:43
BrainstormNew from Contagion Live: President Biden Unveils New “Test to Treat” COVID-19 Strategy: “COVID-19 need no longer control our lives,” President Biden said, detailing a plan to immediately provide free antiviral pills to anyone who tests positive. → https://www.contagionlive.com/view/president-biden-unveils-new-test-to-treat-covid-19-strategy19:02
BrainstormUpdates for Italy: +37946 cases, +214 deaths, +415288 tests (9.1% positive) since a day ago19:09
suenoreceding..19:21
BrainstormNew from Politico: EU explores measures to shelter economy from Russia sanctions blowback: Just as coronavirus emergency measures are winding down, some countries are pushing for another financial safety net. → https://www.politico.eu/article/eu-measures-shelter-economy-russia-sanctions-blowback/19:21
suenoreseeding?19:21
LjLWith this strategy, Biden said, “people can get tested at a pharmacy, and if they’re positive, receive antiviral pills on the spot at no cost.” Biden also said the immunocompromised and other persons at high risk of severe COVID-19 disease will receive treatments and free high-quality masks.19:24
LjL“We’re leaving no one behind or ignoring anyone’s needs as we move forward,” the President said.19:24
LjLThe antiviral pills, manufactured by Pfizer, have been in relatively short supply since they received US Food and Drug Administration (FDA) approval at the end of 2021. Biden promised, “Pfizer is working overtime to get us 1 million pills this month and more than double that next month,” adding that the Pfizer pill reduces the risk of COVID-19-induced hospitalization by 90%.19:24
BrainstormNew from CIDRAP: News Scan for Mar 02, 2022: Long COVID and nerve damage Avian flu in Iowa, Connecticut flocks New gain-of-function research review → https://www.cidrap.umn.edu/news-perspective/2022/03/news-scan-mar-02-202219:31
suenonow if we just had a plan for the rest of the interconnected world, where the variants will come from19:51
BrainstormUpdates for United Kingdom: +44556 cases, +74 deaths since 23 hours ago19:59
BrainstormNew from WebMD: Non-COVID Highlights From Biden’s State of the Union Address: Beyond COVID-19, President Joe Biden on Tuesday hit on several other health care priorities in his first State of the Union, including a warning that the administration would scrutinize private [... want %more?] → https://www.webmd.com/palliative-care/news/20220302/non-covid-highlights-biden-state-of-union20:09
BrainstormNew from COVID19 Vaccine Tracker: valerie: Aivita Biomedical Inc: AV-COVID-19 → https://covid19.trackvaccines.org/vaccines/74/20:19
BrainstormNew from COVID19 Vaccine Tracker: valerie: AIM Vaccine: LVRNA009 → https://covid19.trackvaccines.org/vaccines/189/20:28
BrainstormNew from COVID19 Vaccine Tracker: valerie: Adimmune Corporation: AdimrSC-2f → https://covid19.trackvaccines.org/vaccines/63/20:38
BrainstormNew from Reddit (test): Covid2019: Mutations in SARS-CoV-2 spike protein receptor-binding domains may yield new vaccine-resistant variants → https://old.reddit.com/r/Covid2019/comments/t588po/mutations_in_sarscov2_spike_protein/20:47
BrainstormNew from Reddit (test): CoronaVirus_2019_nCoV: March: Hidden variants | SARS-CoV-2-infected individuals could have different variants hidden in different parts of the body. → https://old.reddit.com/r/CoronaVirus_2019_nCoV/comments/t58962/march_hidden_variants_sarscov2infected/21:07
BrainstormNew from CIDRAP: Survival after in-hospital cardiac arrest 35% lower in COVID-19 patients: Mary Van Beusekom | News Writer | CIDRAP News Mar 02, 2022 The study involved 24,915 US patients with in-hospital cardiac arrest, 24% of whom had COVID-19. → https://www.cidrap.umn.edu/news-perspective/2022/03/survival-after-hospital-cardiac-arrest-35-lower-covid-19-patients21:27
BrainstormUpdates for France: +59312 cases, +189 deaths since 23 hours ago — Spain: +18803 cases, +154 deaths since a day ago — Canada: +58 deaths since 23 hours ago22:05
BrainstormNew from r/COVID19: COVID19: High Viral Specific Antibody Convalescent Plasma Effectively Neutralizes SARS-CoV-2 Variants of Concern → https://old.reddit.com/r/COVID19/comments/t59sb5/high_viral_specific_antibody_convalescent_plasma/22:15
BrainstormNew from CIDRAP: Test to treat, variant vaccines part of new federal COVID-19 plan: Stephanie Soucheray | News Reporter | CIDRAP News Mar 02, 2022 Test to treat will allow patients who test positive to be treated with free antiviral pills on the spot. → https://www.cidrap.umn.edu/news-perspective/2022/03/test-treat-variant-vaccines-part-new-federal-covid-19-plan22:25
BrainstormNew from CIDRAP: Global COVID cases, deaths drop, except in key hot spots: Lisa Schnirring | News Editor | CIDRAP News Mar 02, 2022 Surges continue to intensify in locations such as Hong Kong, where Omicron is still very active. → https://www.cidrap.umn.edu/news-perspective/2022/03/global-covid-cases-deaths-drop-except-key-hot-spots22:34
BrainstormNew from r/Science: science: Vaccinating pregnant women for COVID seems to give future protection to babies.When a mother passes antibodies to her child, it’s known as passive immunity, and this can be generated by a mother being vaccinated or infected during pregnancy. It [... want %more?] → https://old.reddit.com/r/science/comments/t5at4i/vaccinating_pregnant_women_for_covid_seems_to/23:03
BrainstormUpdates for Germany: +198954 cases since 23 hours ago — United Kingdom: +45358 cases, +75 deaths since 23 hours ago23:07
BrainstormNew from COVID on Twitter: Eric Topol (@EricTopol): Neuro-Covid and immune system dysregulation—Disabling peripheral neuropathy in 17 people <1 month after mild Covid nn.neurology.org/content/9/3/e1…—Severe, with autoimmune features, neuronal damage and microglial activationmedrxiv.org/content/10.110… [... want %more?] → https://twitter.com/EricTopol/status/149915150159107277123:42
BrainstormNew from COVID on Twitter: Marc Veldhoen (@Marc_Veld): More data on neurological damage of SARS-CoV-2 infectionSevere Neuro-COVID is associated with peripheral immune signatures, autoimmunity and signs of neurodegeneration: a prospective cross-sectional studymedrxiv.org/content/10.110… → https://twitter.com/Marc_Veld/status/149915442071359898223:51

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