libera/##covid-19/ Wednesday, 2022-02-02

Klindathey extend my green pass by 6 months after I took covid, is it normal? I see some green pass extended for 12 months after took the booster00:03
BrainstormNew from BMJ: Belfast—a personal ȷourney: We went to the cinema last week. Hardly something to write about. But this was different. It was the first time since the start of the pandemic. And it was different in another way too. Usually we go... → http://www.bmj.com/content/376/bmj.o278.short00:11
xxthat's a weird j00:12
xxin that 'journey'00:12
xxseems to be missing a dot above it00:12
LjLxx, ıs ıt? seems perfectly normal to me00:14
xxwell the weird part is that the original source has that dot, but Brainstorm removes it00:14
LjLKlinda, yes, it's normal, it's only extended to about the length of time after which they expect you to get a vaccine shot00:14
xxand no, don't confuse me like that, makes me think my framebuffer is bugged or something00:15
LjLsørry00:15
LjL%u j00:15
BrainstormU+006A LATIN SMALL LETTER J (j)00:15
LjL%u ȷ00:15
BrainstormU+0237 LATIN SMALL LETTER DOTLESS J (ȷ)00:15
xx\_ò< quack00:15
LjLi didn't make Brainstorm do that on purpose00:15
xxso where is it coming from?00:15
LjLi dunno00:15
LjLi'll look at the rss feed00:16
xxall these encoding oddities always make me think someone is trying to exploit some bug, like with the right-to-left code stuff last year00:17
LjLxx, looks like the rss feed is borked http://feeds.bmj.com/bmj/recent00:17
LjL<title><![CDATA[Belfast&#x2014;a personal &#x0237;ourney]]></title>00:18
xx0237 indeed00:18
xxweird that they'd replace it like that00:18
LjLfeedburner is a third party but it's used by a lot of sites00:19
generaalso, it is fat/bold/whatever00:21
xxbut it's missing  ̇00:25
generahttps://en.wikipedia.org/wiki/Dotted_and_dotless_I00:27
xxwell, yeah, but not in the word 'journal'00:27
de-factoKlinda, congratz on PCR testing negative between 10th till 19th day, i hope you are feeling better00:32
TuvixSometimes foreign input can result in odd replacements; you'll see a funkly-looking "i" sometimes when the user is on a Russian keyboard as it's actually a Cyrillic script. Probably not what's going on here, but there are plausable reasons it pops up in traditionally-ASCII venues.00:33
Klindais it big pharma then LjL?00:33
KlindaI mean why if I take it for real I have less days with the one that had the booster?00:34
Klindade-facto: seems I have no negative symptoms00:34
Klindabut I don't really know how to test it, maybe I try to walk 10 km and see00:35
de-factothe level of immunity from infection varies quite a lot, some people get excellent level of antibodies, while some dont get such a good level of antibodies, with vaccination the spread of that distribution is a lot smaller00:35
TuvixI mean, outcomes and how the body reacts is an individual result; statistics are useful in aggregate, but can't predict how a single case will react. Biology is complex, and we're effectively the highest level lifeform on the planet.00:35
LjLKlinda, it has been established that infection alone doesn't offer great protection. infection + vaccine does. so they want you to wait 3 months and then get the vaccine. i don't know what happens to people who catch COVID *after* getting the booster, though...00:36
de-factoso i guess it may be one reason for assuming timespans for immunity, the ability to predict the immunity level within a certain confidence margin, the broader the initial distribution spreads the more limiting the lower immunity cases influence the majority in that category00:37
TuvixOh, maybe I missed the question's purpose; if it's about the delay between infection & vaccination, you can in a way think of an infection as another way to "train" the immune system, just in that case with live virus, not a protein that is similar to one presented with the live virus.00:37
de-factoyes the best level of immunity indeed is infection combined with vaccination00:37
Klindabut is the curret pfizer good for omicron?00:38
Klindaor better wait an update one?00:38
Klindawill they do?00:38
de-factowell didnt you most likely got Omicron infection?00:39
Klindayes I think so00:39
KlindaI mean I didn't lose the smell00:39
Klindaand the taste00:39
BrainstormNew from The Lancet (Online): [Articles] Pandemic preparedness and COVID-19: an exploratory analysis of infection and fatality rates, and contextual factors associated with preparedness in 177 countries, from Jan 1, 2020, to Sept 30, 2021: Efforts to improve pandemic preparedness and [... want %more?] → https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(22)00172-6/fulltext00:40
de-factoso then your antibodies against Omicron-alike versions of SARS-CoV-2 are already raised, but maybe not so much against types that look different to Omicron, e.g. the earlier versions such as Alpha, and Delta, so maybe Wuhan-Hu-1 spikes (the ancestor variant) may broaden your immunity in a way that it also covers variants that are more similar to those?00:41
de-factojust a thought00:41
de-factothat is assuming it was Omicron that you got (which probably is the most likely variant by now in most places)00:41
de-factoyet there was the transition period before00:42
KlindaI don't know, the pepole with the booster that never took the virus got updated with 1 year00:42
Klindabtw I will ask to my medic what he says00:43
de-factoyeah think about what is best for your own protection, not so much about status00:43
de-factowhere are you from again, i forgot00:43
KlindaI mean natural defense isn't better than wi the booster?00:43
Klindaitaly00:44
de-factoah yeah sorry now i remember00:44
de-factoand your contamination when did it happen?00:44
Klinda10 th jaunuary00:45
de-factoyeah then it was in the middle of the big incidence spike in Italy00:45
de-factohttps://www.worldometers.info/coronavirus/country/italy/00:45
de-factoactually almost in the maximum of it00:46
Klindayeee I was in there xD00:46
Klinda-.-00:46
KlindaxD00:46
de-factohence if we can assume that big spike in incidence was caused by Omicron (as in all the other places in Europe) it most likely was Omicron then00:46
TuvixI'm not sure offhand about Italy's recommendations, but in the US you need to at minimum be considered fully-recovered from COVID before you'd be eligible for a booster (or initial vaccination, if someone wanted to pursue primary dosing after.) I presume they have similar guidance for you too, but your medical experts would know best.00:46
KlindaI did 2 doses + infect + booster I have to do?00:47
Klinda4 doses in the end00:47
de-factooh yeah, you already got vaccinated, yeah then... you already should have good immunity against both, the ancestor strains as well as Omicron00:48
Klindain august I finished the second dose, in january I got infected00:49
de-factoi see where you are coming from then, idk if you need booster then, above i assumed you have not seen the vaccine strain00:49
de-factoyeah you should have very good immunity by now, against both ancestor versions and Omicron versions00:50
Klindaso after 6 months I have to take a booster or I don't have the green pass00:50
Klindathat's it00:50
TuvixThere seems to be some value in a delay between later doses. I don't really have any useful info for you for your particular case, but note that it's generally not recommended that a booster be given in 2-dose recipients any earlierl than about 3-5 months out (varies a bit depending on who you ask.) I can't speak for what your doctor might say, but I wouldn't worry about racing out to get a booster dose.00:51
de-factoyeah id wait for that timespan then, in the summer most likely infections (hopefully) will be somewhat rare00:51
de-factoit would make more sense to schedule vaccinations (and boosters) to prepare for the winter seasons, because it will come back (e.g. September, October etc)00:52
Klindaso do you think they will get a update version or not?00:52
TuvixIt's quite likely, just a matter of time to get it produced and approved.00:53
de-factothey will release an Omicron based version, but if you already had that, idk if your benefit from exactly that version is so big. Maybe it will raise (boost) your level against Omicron alike variants, hence also cover offsprings of Omicron that may only be reached by the edges of the variety distribution raised against Omicron (infection and booster vaccination)00:54
TuvixThe overall trend has been for prior varients to have limited protection against future varients, but it's both early in our understanding of Omicron, and we have even less ability to predict what the next varient will bring.00:56
Klindabtw I feel fine, nothing really changed to my body, but who knows the long term effects? :P maybe I should really think it will be fine and that's it00:56
de-factoyou are much less likely to develop anything like long covid because you have been vaccinated prior to infection00:57
de-factoso you most likely will be just fine indeed00:57
Klindabut with the third dose was better if I had it00:58
TuvixBefore exposure? Yea, it would have raised the antibody levels further and began to improve cell-memory further. But your 2-doses is still vastly preferred to going into exposure without any defenses.00:58
TuvixThe protection against infection isn't as strong as protection against hospitalization or death; that's the main purpose of the vaccines.00:59
de-factoit surely is not counter productive to get it, its like "sparring training" for the immune system, but yours already should be quite competent by now i guess00:59
TuvixYou may not have been in a particularly high-risk category, but the vaccines *significantly* improved your odds at having a mild case vs. a more serious set of outcomes.00:59
KlindaI mean with the third dose the immune systems is not more efficient to kill the virus before so can't do more damage?01:00
TuvixIt's largely "too late" to get vaccinated after you've been exposed if that's the question.01:00
TuvixIt can help at preventing the _next_ exposure though. But that's also what your infection has done (and is still doing.)01:00
KlindaI mean if I was with 3 doses my immune system is not more efficient to kill the virus so there is less damage vs 2?01:01
de-facto3 doses make the immune system more competent to kill the virus, boosting does help01:02
TuvixMore or less, yes. All things equal, you want your body to have a robus response. Think of it like an army that's trained very recently, as compared to one that has trained but not for some weeks/months.01:02
Tuvixrobust*01:02
Klindaso yeah I had to take it with the third01:02
TuvixSome army's have "reserve" units. These are units that are not full-time military personell, so they don't train as often. Typically if they are to be deployed in a "real mission" they'll get some extra training before they go. THat training is kind of like what a booster does.01:03
Klindabut I can't go back01:03
KlindaI didn't have the third early cause Pfizer was sold out, there were only moderna01:03
TuvixBUT, to continue the analogy, if all you have is a "reserve army" unit and you need them right *now* to defend against an attack, they're obviously a lot better than nothing.01:03
de-factoyeah right now it won the battle and killed the virus, so a third dose (e.g. with omicron s-protein signature) may remind your immune system later (after some time passed) on how to do that (to omicron based variants)01:03
TuvixYup, exactly that ^. I'm not offering you any professonal medical opinion, but I'd look at a booster, but maybe not worry about that for a number of weeks or even a couple/few months.01:04
TuvixMaybe an updated vaccine will be avialable by then, or guidance may be more clear as we learn more about this virus and Omicron specifically. Your body is really still "learning" from your recent infection.01:04
de-factoMarch or April01:05
de-factosomething like that for an Omicron based BioNTech/Pfizer01:05
de-factoi personally still hope for multivalent vaccines01:05
Klindabut it's also possibile that a third dose will be the same as having 2 doses? maybe in younger like me the immune system remeber well01:06
de-factoi want a shot that included s-protein signatures of *all* the variants we have seen so far, so that my immune system gets trained in identifying every offspring of every variant immediately when it wants to begin to replicate01:06
de-factoa third dose will boost, in any case, question is at what time (and with what s-protein signature) that makes the most sense (and that depends in individual history)01:07
TuvixConsider that vaccines have appeared, so far (with the one mRNA "style" we have avaiable currently) to produce a more broad protection. Infection with live virus seems to do a decent job at short-term protection against reinfection, but not so good a job at defending against a new varient.01:08
Klindaare you happy to get a vaccine after 6 months each time?01:08
de-factoyeah why not? with my booster i almost got no side effects, my arm barely hurt (in comparison to first and second)01:09
TuvixIn a way the latter is a bit more understandable; the varients arise becuase their mutations were more successful at spreading, likely in part to break-through cases (in both prior-exposures and agianst vaccines.) But the vaccines seem to have provided broader response across varients, although the booster appeared necessary in order to preseve the desired level of effectiveness against severe results.01:09
de-factothough infection may also include more epitopes (not only s-protein), so the immunity may be broader, yet the antibodies docking on the spikes are the ones that prevent cell entry (by blocking the docking mechanism)01:11
de-factothats why the vaccines contain spike protein signatures01:12
de-factoyet it would be awesome if they included more versions of it, just one version is... boring to the immune system that already knows that particular version01:13
Klindawhen I had my first dose I had a lot of fear ahaha01:14
Klindawith the second I really didn't care01:14
de-factoif it gets entertained with more variety of s-proteins, it may get motivated to develop a broader variety of antibodies and also try to promote conserved regions (synergistic effects, e.g. if an antibody is able to dock on all the versions)01:14
de-factoi think that this would be quite an improvement01:14
de-factoyeah my third Moderna was the mildest, my arm barely hurt01:15
de-factonothing else, no headache no fatigue01:15
TuvixI had 3 Pfizer, and 3rd gave me effectively no side-effects, just a mildly sore arm for 36 hours or so.01:16
Klindamy medic when I took the virus said like don't worry mostly likely it will attack the superior respiratory parts01:17
TuvixMy first I was a touch light-headed, but frankly I blame my poor planing for that. I was rushed to the appointment due to bad planning earlier in my day, ate a horribly light breakfast, and was probably a bit dehydrated.01:17
Klindaand that's it01:17
TuvixI was fine about 20 minutes after the dose, so I think the rushing to the vaccine clinic and standing in the line for half an hour didn't help matters.01:17
BrainstormNew from COVID on Twitter: Face The Nation (@FaceTheNation): How has the coronavirus pandemic affected America's children and working families?@margbrennan explores with @ProfEmilyOster tomorrow on our first Facebook live at 12:30 PM, ET.Have questions? Let us know with #AskFTN. pic.twitter.com/ta2Jq0apeK → https://twitter.com/FaceTheNation/status/148866339101935206901:18
de-factoi hear from many (vaccinated) here that got Omicron that they got a sore throat and some may loose taste/smell for a few days (but not weeks)01:18
Klindamaybe they lose smell for the cold01:18
KlindaxD01:18
de-factobut then it came back very soon (in days)01:18
TuvixKlinda: Right, the vaccine works to allow the body to more quickly respond to the infection, and by a quicker and more robust response, the virus has less chance to multiply and do more damage to various internal parts that have a greater effect.01:18
TuvixIt sounds like you had both 2-doses and age on your side. Not that the younger can't be impacted, but it's less likely than say an 80 year old with a less-robust immune system. All of these are factors in your favor.01:19
de-factobut then the taste and smell came back very soon (in days)01:19
de-facto(not the virus, of course)01:19
TuvixYes, as you asked earlier you may have done "better" with a booster in addition, but don't forget that you're so much better off than having zero or only a partial priming dose.01:20
Klindawe will see after some years what happens01:20
de-factowe have to make the best out of it01:20
de-factoi quit smoking :D01:20
TuvixIt's easy to look back and wish we'd done something else, but all we can do is use the best informaiton we have now and prepare for the future as most practical.01:20
KlindaI see a factor of long covid could bethat you suffer from diabetes01:21
Tuvixde-facto: Congrats! Pandemic-inspired quit, I take it?01:21
de-factoyep01:21
de-factoin early 202001:21
TuvixKlinda: Possibly, although the data on that is still emerging. In youth in particular (ie: children) that's been reported, although it's also possible infection is merely causing the incidence and markers of diabetes to manifest earlier.01:21
TuvixSome of these interactions may well be that COVID either pronounces or accelerates underlying conditions that cause them to flare up or cause problems earlier than they might have otherwise.01:22
TuvixQuite frankly, the effects of this pandemic are going to be casting long shadows well after the accute phase of the pandemic is over.01:22
Klindabtw in the end one has it's own story that's it, it's like you smoke and I die before than you01:26
Klindasome after covid get some long-term effects, me for example no..01:27
TuvixSure, an outlier doesn't mean the overall statistics are wrong. I could die crossing the road tomorrow, but that won't stop me from looking both ways first just to improve my odds I make it safely!01:27
Klindaora at least anything that looks suspicious01:27
BrainstormNew from NPR Science: A small island nation has cooked up not 1, not 2 but 5 COVID vaccines. It's Cuba!: Cuba has one of the world's highest COVID vaccination rates, with more than 85% of the nation fully immunized and kids as young [... want %more?] → https://www.npr.org/sections/goatsandsoda/2022/02/01/1056952488/a-small-island-nation-has-cooked-up-not-1-not-2-but-5-covid-vaccines-its-cuba01:27
de-factoi think SARS-CoV-2 may have some influence on beta-cells in pancreas (e.g. selectively infecting them or such)01:30
de-factoso it may make sense, though a competent (trained by vaccination and recovery) immune system may prevent such deep penetration and multi-organ spread of the pathogen01:31
TuvixI'm not familiar with that research offhand, although I've certainly seen hints that various organs my be affected by or even accrue virus or at least be damaged by them. Ideally a well-armed immune defense remains the goal to limit the impact of any spread where it's harder for the body to deal with it.01:31
Klindabut it will not recover it after?01:32
KlindaI mean as the immune system destory the enemy01:32
Klindathe body will also restore all01:32
Klindaor at least a good one01:32
de-factothats a good question, if the immune response against SARS-CoV-2 is not so efficient it may also raise some auto-antibodies (e.g. targeting structures of the body) leading to inflammation etc01:33
de-factospeculation: that may be one reason vaccination may help because it directs the immune system towards targeting the s-protein structures01:34
de-factoe.g. lowering the risk of anto-antibodies and thereby all those long lasting symptoms01:34
Klindatomorrow I will walk 10 km01:36
Klindaand see how I am xD01:36
de-factoyeah dont stress your heart though01:36
de-factolook at pulse rates01:36
KlindaI will go slow01:36
de-factoyeah, just saying01:36
Klindabtw I have to go now, see you guys :D thanks sorry for my virus obsession01:39
KlindaxD01:39
TuvixNah, we're all a bit obsessed. It's just more recent/accute of an obsession in your case, understandably.01:40
LjLBrainstorm will lose connectivity for let's say half an hour to an hour01:51
TuvixEye of the (Brain) storm01:52
de-factopoor Brainstorm, hope he is going to be well01:57
xxbrain surgery02:16
LjL-MatrixBrainstorm is just the victim here02:38
LjL-MatrixHis server is working fine, but the ethernet cables plugged into it, not so much02:38
BrainstormNew from COVID on Twitter: Josiah 'So Mild' Grindrod (@JT_Grindrod): "we convinced everyone that covid was the flu, and now we're gonna act shocked when people don't get 3 shots for it even though less than 50% of people get their single flu shot every year" twitter.com/Bob_Wachter/st… → https://twitter.com/JT_Grindrod/status/148868411072165069102:41
* de-facto pets Brainstorm02:54
* Brainstorm starts to mollify de-facto with some productive infective agent 02:54
de-factoahm is that a biohazard?02:55
de-factoBrainstorm are you ok?02:55
* de-facto sanitizes Brainstorm02:57
* Brainstorm starts to stick de-facto with some uncoated bully 02:57
de-factolol02:57
BrainstormNew from r/WorldNews: worldnews: Nunavut Inuit who get vaccinated against COVID-19 could win a snowmobile in draw → https://old.reddit.com/r/worldnews/comments/sibuex/nunavut_inuit_who_get_vaccinated_against_covid19/03:00
xxI wanna win a snowmobile03:01
maenadyep at the gym today, they asked for vax card03:15
maenad"went viral" should mean anti-vaxer died of covid03:28
BrainstormNew from r/Science: science: Students from low-income families are increasingly isolated in the nation’s schools, complicating efforts to remedy ‘learning loss’ during the pandemic, study finds → https://old.reddit.com/r/science/comments/sibzik/students_from_lowincome_families_are_increasingly/03:38
BrainstormNew from COVID on Twitter: Josiah 'So Mild' Grindrod (@JT_Grindrod): I feel like we're only a few steps away from mandatory SARS infections in a vain attempt to gain "endemicity" → https://twitter.com/JT_Grindrod/status/148870376436617216203:48
BrainstormNew from COVID on Twitter: Josiah 'So Mild' Grindrod (@JT_Grindrod): The only "armchair epidemiologists" I see are ivory tower assholes that have worked from home for the last two years and have everything delivered to them while telling everyone else to go die for the economy and declaring the end of the pandemic. → https://twitter.com/JT_Grindrod/status/148870723383148134703:57
BrainstormNew from COVID on Twitter: Will Saletan (@saletan): Excellent thread, explaining why Denmark is lifting COVID restrictions.This is a goal that can unite us: a society in which vaccination is so pervasive that people feel confident resuming normal life. In-person school, no lockdowns, no mask mandates. Vaccination [... want %more?] → https://twitter.com/saletan/status/148870810359608525304:07
BrainstormNew from COVID on Twitter: Liz Carey (@AstroLizzy):  I, too, love people who are at high risk and have loved ones who are dealing with long Covid. I’m so tired of this being implied as “irrational”. What IS irrational is being fine with SARS running wild. Oh, and hard pass on the brain damage too twitter.com/nbedera/status… → https://twitter.com/AstroLizzy/status/148871095369678438904:16
BrainstormNew from COVID on Twitter: Eric Topol (@EricTopol): Lowest US Covid hospitalizations in a monthFrom the pandemic peak near 160,000, down to 126,000 today pic.twitter.com/a1TRTDmsOm → https://twitter.com/EricTopol/status/148871295150673510504:26
TuvixUm, hmm, I wonder what source Topol is getting that from. The lowest since the start of 2022 appears to be Jan-1 with just shy of 83k currently hospitalized, at least going by CDC's trends: https://covid.cdc.gov/covid-data-tracker/#trends_dailydeaths_currenthospitaladmissions04:30
TuvixOh, his chart looks the same as the linked CDC plot, so I have no idea how he's concluding 126k today is the "lowest US Covid hospitalizations in a month" based on that though.04:32
BrainstormNew from COVID on Twitter: Michael Lin, MD PhD  (@michaelzlin): Above, the JJ+Pfizer looked about 2x worse than 3xPfizer. Confidence intervals are wide, but another underreported Omicron study found JJ+Pfizer was ~3x worse than Mod+Mod+Pfizer. So this effect size seems consistent.Great graphics [... want %more?] → https://twitter.com/michaelzlin/status/148872742181360435305:17
BrainstormNew from r/WorldNews: worldnews: Beijing Olympics’ COVID cases mounting at faster pace than Tokyo → https://old.reddit.com/r/worldnews/comments/sifag5/beijing_olympics_covid_cases_mounting_at_faster/05:36
BrainstormNew from COVID on Twitter: Michael Lin, MD PhD  (@michaelzlin): And they also looked at T cell responses across strains. Again Moderna much better than everything else. Little differences across strains (because T cell epitopes are from anywhere in the protein, and not subject to the same selective pressure) [... want %more?] → https://twitter.com/michaelzlin/status/148873440168912486405:45
BrainstormNew from COVID on Twitter: Michael Lin, MD PhD  (@michaelzlin): So the de Vries study is remarkably consistent in showing Moderna to have the broadest B cell responses, and the strongest B and T cell responses. It does seem like the most protective of the vaccines, and Modernites also get to enjoy a 3rd shot of [... want %more?] → https://twitter.com/michaelzlin/status/148873440341298790505:55
* enyc hrrms at the new-omicron muddle06:59
BrainstormNew from r/WorldNews: worldnews: America’s covid job-saving programme gave most of its cash to the rich → https://old.reddit.com/r/worldnews/comments/sigpxs/americas_covid_jobsaving_programme_gave_most_of/07:00
BrainstormUpdates for United States: +11529136 cases, +45226 deaths, +55301732 tests (20.8% positive) since 14 days ago — France: +6333115 cases, +4788 deaths, +24115858 tests (26.3% positive) since 14 days ago — India: +5059462 cases, +12953 deaths, +35128359 tests (14.4% positive) since 14 days ago — Italy: +2960777 cases, +6737 deaths, +19359502 tests (15.3% positive) since 14 days ago07:02
BrainstormNew from r/WorldNews: worldnews: Indian health workers allege widespread vaccine certificate fraud → https://old.reddit.com/r/worldnews/comments/sii13b/indian_health_workers_allege_widespread_vaccine/08:15
BrainstormNew from r/WorldNews: worldnews: U.S. Has Far Higher Covid Death Rate Than Other Wealthy Countries → https://old.reddit.com/r/worldnews/comments/siiqs7/us_has_far_higher_covid_death_rate_than_other/08:54
BrainstormNew from r/Coronavirus: Daily Discussion Thread | February 02, 2022: Please refer to our Wiki for more information on COVID-19 and our sub. You can find answers to frequently asked questions in our FAQ , where there is valuable information such as our: → https://old.reddit.com/r/Coronavirus/comments/sij397/daily_discussion_thread_february_02_2022/09:03
BrainstormNew from r/WorldNews: worldnews: Denmark Declares Covid No Longer Poses Threat to Society → https://old.reddit.com/r/worldnews/comments/sijwph/denmark_declares_covid_no_longer_poses_threat_to/10:10
BrainstormNew from StatNews: Health: Despite Biden’s big promises and a far better understanding of the virus, Covid-19 is still raging through the nation’s prisons → https://www.statnews.com/2022/02/02/biden-promises-covid19-prisons/10:39
BrainstormNew from StatNews: Opinion: Race alone should not be used to allocate scare Covid-19 treatments: If the CDC and states fail to provide fair and transparent guidance on ethical allocation of scarce Covid-19 treatments, it will force doctors to make these decisions and [... want %more?] → https://www.statnews.com/2022/02/02/race-alone-should-not-be-used-to-allocate-scare-covid-19-treatments/10:49
BrainstormUpdates for France: +1230 cases since 3 hours ago — Solomon Is.: +3 deaths since 3 hours ago10:59
BrainstormNew from BMJ: People carrying excess weight have an increased risk of severe covid-19: The studyGao M, Piernas C, Astbury NM, et al. Associations between body-mass index and COVID-19 severity in 6.9 million people in England: a prospective, community-based cohort study. Lancet Diabetes... → http://www.bmj.com/content/376/bmj.o141.short11:27
BrainstormNew from COVID on Twitter: Marc Veldhoen (@Marc_Veld): SARS-CoV-2 infection turning points seem to have been reached in the high vax countries; DK, PT, IR. It is likely to reduce rapidly but will settle at a lower rate. pic.twitter.com/m54Ye74neF → https://twitter.com/Marc_Veld/status/148882695320549377111:56
BrainstormUpdates for Kiribati: +138 cases since 4 hours ago12:02
BrainstormNew from Retraction Watch: Paper overestimated risk of COVID-19 to endangered apes: A Springer Nature journal has retracted a 2021 article with dire news for mountain gorillas in Rwanda’s Volcanoes National Park about the prospects of extinction on the spikes of SARS-CoV-2 [... want %more?] → https://retractionwatch.com/2022/02/02/paper-overestimated-risk-of-covid-19-to-endangered-apes/12:05
BrainstormNew from r/COVID19: COVID19: An intranasal lentiviral booster broadens immune recognition of SARS-CoV-2 variants and reinforces the waning mRNA vaccine-induced immunity that it targets to lung mucosa → https://www.reddit.com/r/COVID19/comments/sim2ej/an_intranasal_lentiviral_booster_broadens_immune/12:15
BrainstormNew from ScienceNews: Health & Medicine: A faulty immune response may be behind lingering brain trouble after COVID-19 → https://www.sciencenews.org/article/covid-brain-fog-coronavirus-immune-response-fatigue13:03
BrainstormNew from The Atlantic: Everything Hard About Health Care Now, in One Chicago Hospital: At the height of the recent Omicron surge, Advocate Trinity Hospital, in Chicago, was inundated with patients who spent more than 40 hours in the waiting room, holding tight for a bed in the [... want %more?] → https://www.theatlantic.com/health/archive/2022/02/omicron-surge-hospital-chicago/621455/13:13
BrainstormNew from ECDC: ECDC: Data on the daily number of new reported COVID-19 cases and deaths by EU/EEA country → https://www.ecdc.europa.eu/en/publications-data/data-daily-new-cases-covid-19-eueea-country13:32
BrainstormNew from COVID on Twitter: Dr Emma Hodcroft (@firefoxx66): Handed in my big @snsf_ch Starting Grant proposal yesterday - what a feeling!! To illustrate the impact of grant-writing, here was my January (almost entirely grant writing + pandemic/ CoVariants.org) as seen via my mood/activity tracking app @hellodaylio  [... want %more?] → https://twitter.com/firefoxx66/status/148885682930422579413:51
BrainstormNew from COVID on Twitter: Marc Veldhoen (@Marc_Veld): "The rate of confirmed infection was lower in people 12 or more days after their fourth dose than amongthose who received only three doses and those 3 to 7 days after vaccination by factors of 2.0 and 1.9, respectively."That is not strange and are the increase [... want %more?] → https://twitter.com/Marc_Veld/status/148885813653027635614:01
BrainstormNew from COVID on Twitter: Scott Gottlieb, MD (@ScottGottliebMD): Another year with exceptionally low flu prevalence. At a time when we’ve reduced spread of flu to historically low levels through respiratory precautions taken societally, covid still has spread uncontrollably and caused excessive death. What [... want %more?] → https://twitter.com/ScottGottliebMD/status/148886270788132864414:20
BrainstormNew from COVID on Twitter: Eric Topol (@EricTopol): "Since December 1...the share of Americans who have been killed by the coronavirus is at least 63% higher than in any of these other large, wealthy nations."nytimes.com/interactive/20… pic.twitter.com/cC96XBa962 → https://twitter.com/EricTopol/status/148886799172274176214:39
BrainstormNew from Reddit (test): nCoV: STAT Coronavirus Coverage | a good mix of articles related to the virus, disease, and pandemic | 02FEB22 → https://old.reddit.com/r/nCoV/comments/sip0se/stat_coronavirus_coverage_a_good_mix_of_articles/14:49
BrainstormNew from Reddit (test): nCoV: Tonga lockdown begins as COVID arrives with aid after volcanic eruption, tsunami | 02FEB22 → https://old.reddit.com/r/nCoV/comments/sip6cb/tonga_lockdown_begins_as_covid_arrives_with_aid/14:59
BrainstormNew from Contagion Live: Moderna, IAVI Testing mRNA Technology for HIV Vaccine: Researchers could be one step closer to an HIV vaccine. This one uses mRNA technology. → https://www.contagionlive.com/view/moderna-iavi-testing-mrna-technology-for-hiv-vaccine15:09
BrainstormUpdates for Switzerland: +31708 cases, +9 deaths, +111606 tests (28.4% positive) since 8 hours ago15:09
BrainstormNew from Reddit (test): nCoV: Coronavirus, During Mutation, Lost Ability To Penetrate Into Lung Tissue -Russian Watchdog | 02FEB22 → https://old.reddit.com/r/nCoV/comments/sipu21/coronavirus_during_mutation_lost_ability_to/15:28
BrainstormNew from COVID on Twitter: Dr Emma Hodcroft (@firefoxx66): A nice piece by @meredithwadman covering what we know - and don't yet know - about BA.2 (21L #BA2).science.org/content/articl… → https://twitter.com/firefoxx66/status/148888552754159616615:48
Dreddhttps://www.principletrial.org/ -> and they say no one tried ivermectin 😛15:51
BrainstormUpdates for Germany: +7277 cases since 8 hours ago — Palau: +130 cases, +3174 tests (4.1% positive) since 8 hours ago — Canada: +274 cases, +2 deaths since 8 hours ago15:59
BrainstormNew from COVID on Twitter: Prof. Akiko Iwasaki (@VirusesImmunity): I am excited to participate in this @HealthNYGov consortium on #longCOVID tomorrow. I will be on the first panel on LC research with Drs. @mhornig, Jennifer Frontera, @Lpurpura3, Michael Roehrl moderated by Dr. Eli Rosenberg.Register free [... want %more?] → https://twitter.com/VirusesImmunity/status/148889096801955021216:08
BrainstormNew from COVID on Twitter: Bloom Lab (@jbloom_lab): Overall antigenic cartography similar between studies (below vs image in Tweet 3/n). Omicron placement probably poorly constrained due to low titers from all sera, but among other variants both place Beta and Delta far apart consistent w @sigallab [... want %more?] → https://twitter.com/jbloom_lab/status/148889215206295552716:17
xxDredd: ivermectin should be as easily available as aspirin, at least we'd get rid of the hidden epidemic of parasites in the west16:18
undefined_boblol yes16:19
Dreddhttps://www.newscientist.com/article/2302731-uk-has-begun-using-drugs-for-covid-19-cases-before-they-become-severe/16:20
DreddIn that talking about molnupiravir it has "David Lowe at University College London, who is involved in the trial, says mutations aren’t a big worry. “Once you’ve given [the drug] for a few days, the level of infectious virus is so low that you can’t even culture it. But it is something that we need to keep an eye on,” he says."16:21
DreddThat's the first time I've heard something like that but it's good news if so16:21
Dreddde-factoLjL you might be interested in ^16:21
Dreddxx: In the UK there are anti-parasitics available over the counter I think16:22
xxDredd: last I checked it was some medicine beginning with 'a', not ivermectin16:22
DreddAnd that matters?16:23
DreddIf it works then its all good16:23
xxyeah, because it only worked against lice or something16:23
Saltssaumureisn't that just lice shampoo?16:23
xxinstead of internal parasites16:23
DreddThat's not what I'm talking about - they are usually sold for worms16:24
xxmaybe, it's been a great many years since I lived in UK16:24
Dreddhttps://www.nhs.uk/medicines/mebendazole/16:24
DreddThis maybe16:24
xxAlbendazole I think16:27
BrainstormNew from COVID on Twitter: Eric Topol (@EricTopol): Our covid timesby @stephanpastis pic.twitter.com/Fu4uIINFft → https://twitter.com/EricTopol/status/148889425585881497616:27
DreddThere might be different ones available even, but the point is that things are available to people who need them16:29
DreddI'm not convinced there is a hidden harmful parasite pandemic going on in the UK at least anyway 🤷16:29
Saltssaumurebug ass16:47
BrainstormNew from COVID on Twitter: Nussenzweig_LAB (@NussenzweigL): Our newest preprint describes the incredible diversity of the memory B cell response that can neutralize #SARSCoV2 by targeting the N-terminal domain and provide protection against variants including Omicron twitter.com/biorxiv_immuno… → https://twitter.com/NussenzweigL/status/148890098690318745916:47
BrainstormNew from COVID on Twitter: Eric Topol (@EricTopol): What if there was a way to prevent 99% of Covid deaths and 96%  hospitalizations, safety was validated in billions of people, it was free, and there was an unlimited supply?There is. 3 shots. But tens of millions of Americans won’t go for it.And the US outcomes [... want %more?] → https://twitter.com/EricTopol/status/148890825755278131717:16
xx^ at some point we'll have to accept that it is people's choice to not take the vaccine, and that they choose to bear the consequences too17:25
xxcan't really force people to do something with their own body that they don't want to do17:26
edcbathe main problem is we are still the ones paying for it17:28
xxwell we shouldn't be17:30
whytekyeah17:32
whytekdefine "free" there17:32
whytekthat's BS17:32
whyteknot free, never was, never will be.17:32
BrainstormNew from COVID on Twitter: Florian Krammer (@florian_krammer): Here is an IRB approved advertisement for our NDV-HXP-S vaccine study in New York. pic.twitter.com/3RXdHFxAGp → https://twitter.com/florian_krammer/status/148891185554018713817:36
BrainstormNew from COVID on Twitter: Michael Lin, MD PhD  (@michaelzlin): “We are working hard and HHS is working hard every day to get Dr. Califf [confirmed],” the White House spokesperson said. “We believe it is extremely important to have a confirmed head of the FDA in the midst of the pandemic.”Agree with the [... want %more?] → https://twitter.com/michaelzlin/status/148891802239581388817:55
Tuvixwhytek: Free as in won't cost the citizen any money; this is actually quite crucial during a public health crisis to avoid disparities for the less able to pay for themselves, including the poor, unemployed, homeless, and so on.18:01
TuvixIf these populations aren't protected, they become not only an underserved class during a health crisis, but also will end up contributing to the spread of the diseas and possibly the generation & spread of new mutations.18:02
BrainstormUpdates for Netherlands: +66969 cases, +10 deaths since 11 hours ago — Solomon Is.: +681 cases since 11 hours ago18:04
BrainstormNew from COVID on Twitter: Eric Topol (@EricTopol): 99% less deathstwitter.com/EricTopol/stat…96% less hospitalizationstwitter.com/EricTopol/stat…BTW Substantial reduction of #LongCovid → https://twitter.com/EricTopol/status/148891835010942976218:05
TuvixThis is quite a common use of the word free; I can go to my local park for free. Sure, its upkeep is funded by city taxes, but I don't have to pay to use the land or facilities. Others from different cities who don't contribute at all may use them, also without charge.18:06
dzhohttps://en.wikipedia.org/wiki/Common-pool_resource#Definition_matrix18:09
TuvixOh neat, that's a nice way to look at this. Sure, so by that definition framework, we could even say vaccines started as a Rivalrous Non-excludable resource, and supplies were initially limited to those eligible who faced the greatest risk (healthcare staff, frontline workers, those exposed to people at their job, and so on.) Once supply became available, it transitioned to a Non-rivalrous Non-excludable18:15
Tuvixresource.18:15
BrainstormNew from r/WorldNews: worldnews: Quebec scraps proposed tax on the unvaccinated, announces gyms and spas can reopen → https://old.reddit.com/r/worldnews/comments/siu6xl/quebec_scraps_proposed_tax_on_the_unvaccinated/18:34
BrainstormNew from r/WorldNews: worldnews: Fort Bragg 82nd Airborne Division paratroopers, 18th Airborne Corps soldiers head to Europe → https://old.reddit.com/r/worldnews/comments/siuabn/fort_bragg_82nd_airborne_division_paratroopers/18:44
BrainstormUpdates for Italy: +119323 cases, +395 deaths, +964521 tests (12.4% positive) since 12 hours ago — United Kingdom: +5 deaths, +2592697 tests (0.0% positive) since 12 hours ago19:06
BrainstormNew from COVID on Twitter: Eric Topol (@EricTopol): Results of the 1st #SARSCoV2 human challenge trialft.com/content/d6fd08… Infectiousness begins quickly and  lasts long (ancestral strain was used) pic.twitter.com/rEfr1JUIna → https://twitter.com/EricTopol/status/148893681145167462419:13
BrainstormNew from COVID on Twitter: Marc Veldhoen (@Marc_Veld): What the Omicron wave is revealing about human immunityAn excellent reviewnature.com/articles/d4158… → https://twitter.com/Marc_Veld/status/148894166190442496419:33
BrainstormNew from COVID on Twitter: Tulio de Oliveira (@Tuliodna): The key metrics to follow now are not infections or attack rates but hospitalization, vaccination, and carrying capacity of hospitals. If we increase vaccination and carrying capacity of hospitals we can manage new variants (as we did in South Africa with [... want %more?] → https://twitter.com/Tuliodna/status/148894592785967923919:52
xxnot if new variants are worse than anything we've seen so far19:58
BrainstormUpdates for Canada: +4564 cases, +128 deaths since 13 hours ago20:02
Timvdexx: then that will soon be visible in the hospitalisations, I suppose20:05
xxand every politician will say "We couldn't have predicted this, nothing could have been done to prepare for it"20:05
BrainstormNew from COVID on Twitter: Devang Mehta ‍ (@drdevangm): "Dr Coates’ analysis found that 82.8% of coronavirus-related preprints and 92.8% of non-coronavirus-related preprints saw no material change to their conclusions upon journal publication."So much for the "peer review adds value to the paper" [... want %more?] → https://twitter.com/drdevangm/status/148895005962241229320:11
BrainstormNew from COVID19 Vaccine Tracker: valerie: Altimmune Inc: AdCOVID → https://covid19.trackvaccines.org/vaccines/75/20:22
BrainstormNew from COVID19 Vaccine Tracker: valerie: Arcturus Therapeutics Inc: ARCT-165 → https://covid19.trackvaccines.org/vaccines/148/20:32
BrainstormNew from COVID on Twitter: Michael Lin, MD PhD  (@michaelzlin): The study came out on 12/25. It contains the data behind Novavax's 12/22 announcement that 3 shots of their vaccine provided Omicron protection. That got into the news, but nobody came back on Christmas to write about the actual findings (I wonder [... want %more?] → https://twitter.com/michaelzlin/status/148895893563771289720:42
BrainstormNew from COVID19 Vaccine Tracker: valerie: Arcturus Therapeutics Inc: ARCT-154 → https://covid19.trackvaccines.org/vaccines/140/20:52
BrainstormNew from COVID on Twitter: Michael Lin, MD PhD  (@michaelzlin): Is there anything from the "intepretation" that you remember from reading it? It's so bland/vague that it leaves you with no understanding at all. The title is of no help too. Could have been "A third dose of NVX-CoV2373 induces broad immune responses [... want %more?] → https://twitter.com/michaelzlin/status/148896581878004531221:11
BrainstormNew from COVID19 Vaccine Tracker: valerie: AnGes: AG0301-COVID19 → https://covid19.trackvaccines.org/vaccines/3/21:21
BrainstormNew from COVID on Twitter: Michael Lin, MD PhD  (@michaelzlin): nAb levels look slightly worse; some of the vaccinated after 2 doses with lower total Abs don't show neutralization. But there is still some activity to all variants including Omicron.Would be great to have some numbers, right? Oh, they're in a [... want %more?] → https://twitter.com/michaelzlin/status/148897124121821184021:30
BrainstormNew from COVID on Twitter: Michael Lin, MD PhD  (@michaelzlin): They also looked at unboosted nAbs against Omicron. This is a measure of breadth of the response. Convalescent sera and Moderna neutralized Omicron the most (look at #'s above), everyone else poor. pic.twitter.com/Foqbnich4q → https://twitter.com/michaelzlin/status/148897496112965222521:40
BrainstormNew from COVID on Twitter: Eric Topol (@EricTopol): New @CellCellPress A mechanism for Covid loss of smell: disruption of nuclear architecturesecure.jbs.elsevierhealth.com/action/getShar… pic.twitter.com/sTK5fr6L1h → https://twitter.com/EricTopol/status/148897655363558195421:50
BrainstormNew from COVID19 Vaccine Tracker: valerie: Aivita Biomedical Inc: AV-COVID-19 → https://covid19.trackvaccines.org/vaccines/74/21:59
BrainstormNew from COVID on Twitter: Michael Lin, MD PhD  (@michaelzlin): Things get even better after a 3rd shot of Novavax. There the levels of anti-Omicron nAbs are 214; that's even higher than the 120 for anti-ancestral nAbs that gave 95% VE. So you might predict 3 doses of Novavax will give >95% VE against Omicron. [... want %more?] → https://twitter.com/michaelzlin/status/148898468505335808022:22
BrainstormNew from COVID on Twitter: Michael Lin, MD PhD  (@michaelzlin): The "interpretation" said "For... all variants evaluated, immune responses following the booster were notably higher than those associated with high levels of efficacy in phase 3 studies"Much too vague. Just say: nAb levels against Omicron exceeded [... want %more?] → https://twitter.com/michaelzlin/status/148898542591394201722:28
BrainstormNew from COVID on Twitter: Michael Lin, MD PhD  (@michaelzlin): It's been an open question whether we can make a vaccine that can elicit a significant response to that epitope. Perhaps that is what Novavax is doing. And why might it be doing that? → https://twitter.com/michaelzlin/status/148898855860184678422:38
BrainstormNew from COVID on Twitter: Eric Topol (@EricTopol): The results are nearly identical with the 1st human challenge study reported today, with formal assessment of viral load, rapid tests, lack of correlation with symptoms, and length of time to lack of infectiousness twitter.com/EricTopol/stat… → https://twitter.com/EricTopol/status/148899086491113062722:48
BrainstormNew from COVID on Twitter: Eric Topol (@EricTopol): Just out @NEJM There are many confounding factors when trying to assess Omicron's intrinsic severity, particularly the immunity wall already built by prior infection and vaccinations, exposing a very large N at low risknejm.org/doi/full/10.10… by @roby_bhatt [... want %more?] → https://twitter.com/EricTopol/status/148899564465630822723:07
BrainstormNew from CIDRAP: US COVID-19 cases drop, but hospitalizations in unvaccinated still high: Stephanie Soucheray | News Reporter | CIDRAP News Feb 02, 2022 Daily cases have dropped 36%, hospitalizations have dipped 14%, and deaths are down 4%. → https://www.cidrap.umn.edu/news-perspective/2022/02/us-covid-19-cases-drop-hospitalizations-unvaccinated-still-high23:17
BrainstormNew from COVID on Twitter: Marc Veldhoen (@Marc_Veld): Nice explainer why it is now so difficult to assess the pathogenicity of Omicron. The confounding factors are enormous and these can quickly result in overinterpretation.Challenges in Inferring Intrinsic Severity of the SARS-CoV-2 Omicron Variant nejm.org/doi/full/10.10… → https://twitter.com/Marc_Veld/status/148900093461736243623:26
BrainstormNew from COVID on Twitter: Eric Topol (@EricTopol): How durable are 3rd/booster shot-induced neutralizing antibodies vs Omicron in elderly people?81% of individuals, median age 82, maintained detectable activity at 4.5 months2 shots: nearly absentmedrxiv.org/content/10.110…by @kvanshylla and colleagues [... want %more?] → https://twitter.com/EricTopol/status/148900324414778982623:36
LjL"4.5 months" is the new "yay"?23:37
xx"detectable"23:38
LjLwell that means they may not even be enough to fend anything23:38
xxexactly23:38
LjLbut even if they do, 4.5 months isn't exactly grandious23:40
xxprobably should have been timed better and administered before the winter season23:40
xxinstead of *now*23:40
BrainstormNew from CIDRAP: First COVID-19 human challenge study yields infection clues: Lisa Schnirring | News Editor | CIDRAP News Feb 02, 2022 COVID-19 has a shorter incubation period than thought, and rapid tests performed well. → https://www.cidrap.umn.edu/news-perspective/2022/02/first-covid-19-human-challenge-study-yields-infection-clues23:46
LjLxx, tbf i had my booster a fair amount of time before "now"!23:47
LjLbut yeah not quite before winter23:48

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